Skelaxin (Metaxalone) - Side Effects and Adverse Reactions

Adverse Reactions

The most frequent reactions to metaxalone include:

CNS: drowsiness, dizziness, headache, and nervousness or “irritability”;

Digestive: nausea, vomiting, gastrointestinal upset.

Other adverse reactions are:

Immune System: hypersensitivity reaction, rash with or without pruritus;

Hematologic: leukopenia; hemolytic anemia;

Hepatobiliary: jaundice.

Though rare, anaphylactoid reactions have been reported with metaxalone.

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO SKELAXIN

Possible Skelaxin side effects / adverse reactions in 58 year old female

Reported by a physician from United States on 2007-05-02

Patient: 58 year old female weighing 128.8 kg (283.4 pounds)

Reactions: Drug Interaction, Narcotic Intoxication, Troponin Increased, False Positive Laboratory Result

Adverse event resulted in: hospitalization

Suspect drug(s):
Opana
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Opana ER
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Skelaxin
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Trazodone HCL
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Vistaril
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Other drugs received by patient: Ambien; Quinine Sulfate; Sinemet; Insulin; Januvia; Amaryl; Ultram

Possible Skelaxin side effects / adverse reactions in 58 year old female

Reported by a physician from United States on 2007-05-02

Patient: 58 year old female weighing 128.8 kg (283.4 pounds)

Reactions: Drug Toxicity, Confusional State, Drug Interaction, Troponin Increased, False Positive Laboratory Result

Adverse event resulted in: hospitalization

Suspect drug(s):
Opana ER
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Opana
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Skelaxin
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Trazodone HCL
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Vistaril
    Indication: Drug USE FOR Unknown Indication
    End date: 2007-04-01

Other drugs received by patient: Ambien; Quinine Sulfate; Sinemet; Insulin; Januvia; Amaryl; Ultram

Possible Skelaxin side effects / adverse reactions in 79 year old male

Reported by a consumer/non-health professional from United States on 2007-06-25

Patient: 79 year old male weighing 95.3 kg (209.6 pounds)

Reactions: Presyncope, Dizziness

Adverse event resulted in: life threatening event

Suspect drug(s):
Skelaxin

Other drugs received by patient: Propoxyphene Hydrochloride