NEWS HIGHLIGHTSMedia Articles Related to Sinografin (Diatrizoic Acid / Iodipamide Intrauterine)
APA Leaders Defend New Diagnostic Guide
Source: MedPage Today Cardiovascular [2013.05.18]
SAN FRANCISCO (MedPage Today) -- The fifth edition of the "psychiatrist's bible" was officially released here in all its 947-page glory, with its developers offering a spirited rebuttal to their critics.
Topol on Using Smartphones for Complex Diagnostic Challenges
Source: Medscape Allergy & Clinical Immunology Headlines [2013.05.15]
Eric J. Topol, MD, describes how smartphones and supercomputers will partner to help clinicians with challenging medical diagnoses and treatments.
Medscape
FDA Approves New Lung Cancer Diagnostic "Cobas EGFR Mutation Test"
Source: Cancer / Oncology News From Medical News Today [2013.05.15]
The U.S. Food and Drug Administration (FDA) has approved the cobas EGFR Mutation Test, a companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved companion diagnostic that detects epidermal growth factor receptor (EGFR) gene mutations, which are present in approximately 10 percent of non-small cell lung cancers (NSCLC)...
Medical Diagnostic Device Employs Wireless Signals To Identify Brain Swelling Or Bleeding
Source: Medical Devices / Diagnostics News From Medical News Today [2013.05.15]
New technology developed at the University of California, Berkeley, is using wireless signals to provide real-time, non-invasive diagnoses of brain swelling or bleeding. The device analyzes data from low energy, electromagnetic waves, similar to the kind used to transmit radio and mobile signals...
FDA Approves Companion Genetic Diagnostic Test for Tarceva
Source: Medscape Today Headlines [2013.05.14]
The FDA has approved the first companion diagnostic test that can detect EGFR mutations in non-small cell lung cancer.
FDA Approvals
Published Studies Related to Sinografin (Diatrizoic Acid / Iodipamide Intrauterine)
Dry powdered aerosols of diatrizoic acid nanoparticle agglomerates as a lung contrast agent. [2010.05.31]
Aerosolized contrast agents may improve the resolution of biomedical imaging modalities and enable more accurate diagnosis of lung diseases. Many iodinated compounds, such as diatrizoic acid, have been shown to be safe and useful for radiographic examination of the airways...
Clinical Trials Related to Sinografin (Diatrizoic Acid / Iodipamide Intrauterine)
(Gastrografin Use in Small Bowel Obstruction Caused by Adherences) [Completed]
Adhesive small intestine obstruction (ASIO) is an important cause of hospital admission and a
very common disease. Any improvement in this field will benefit many patients by reducing the
operative rate. Patients with this disease are difficult to evaluate and to manage and their
treatment is controversial. Emergency surgery is mandatory when strangulation is suspected or
in the case of total obstruction. On the other hand, conservative non-operative treatment is
indicated in the case of partial obstruction. The role of water-soluble contrast medium
(Gastrografin®: GG) in ASIO is still debated with regard to the therapeutic value.
The aim of our study was to determine the therapeutic role of Gastrografin in patients with
small intestine obstruction without strangulation caused by adherences (ASIO).
Value of CT-Scan and Oral Gastrografin in the Management of Post Operative Small Bowel Obstruction [Recruiting]
Small bowel obstructions are responsible for 2 to 5% of emergency hospital admissions and
20% of all emergency surgical procedures. In 60 to 80% of cases, acute small bowel
obstructions are the consequence of intraperitoneal postoperative adhesions. They constitute
an extremely frequent pathology, leading to a high rate of hospital admissions and money
expense.
Management of small bowel obstruction is based on 2 options: either a surgical approach
where all patients are operating on, or a conservative treatment in which surgery is
proposed in case of failure of medical treatment. The surgical approach leads to operate on
an excessive rate of patients while the medical approach increases the risk of increased
small bowel resection, morbidity rate or hospitalization duration.
In order to improve the management of small bowel obstruction, it seems necessary to better
distinguish patients that need an emergency surgical procedure from patients in which
medical treatment will be useful. Many studies have been performed to investigate the value
of imaging in the management of small bowel obstruction, using abdominal X-ray, oral
gastrografin administration or CT-Scan.
The aim of this study is to analyse the effect of a systematic performance of imaging
investigation on the management of patients presenting with a postoperative small bowel
obstruction.
All patients suffering from a postoperative small bowel obstruction will be included in this
study. They will be randomised in 2 groups. In group S, patients will have CT-Scan and oral
water administration while in group SG, Patients will have CT-Scan and oral gastrografin
administration The major end point of this study is to analyse whether imaging examination
can reduce the need for a surgical approach or the rate of small bowel resection and to
determine its influence on fasting time or hospitalization duration
Safety Study of Autologous Stem Cell in Liver Cirrhosis [Terminated]
It is a fase I/II clinical study to evaluate feasibility, safety and kinetics of cellular
therapy with bone marrow-derived mononuclear cells (ABMMC) in patients with liver cirrhosis.
All the patients have moderate liver disfunction and a waiting time expectancy of liver
transplantation longer than 12 months due their low MELD score. The ABMMC are labeled with
99mTc and infused through the hepatic artery. Scintigraphy is performed 2 and 24 hours after
infusion. Patients are submitted to frequent clinical, laboratorial and image evaluation
during the follow up period of 12 months.
Autologous Transplantation of Bone Marrow Mononuclear Stem-Cells by Mini-Thoracotomy [Completed]
Bone marrow mononuclear cells (BMMC) transplantation is a promising therapy for treating
ischemic disease, however the effect in non-ischemic dilated cardiomyopathy is unknown. This
study describes a technique of BMMC transplantation utilizing mini-thoracotomy and results up
to one year after the procedure.
Stem Cell Transplantation for the Treatment of Knee Osteoarthritis [Recruiting]
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