ADVERSE REACTIONS
Most adverse reactions occurring during therapy with Seromycin involve the nervous system or are manifestations of drug hypersensitivity. The following side effects have been observed in patients receiving Seromycin: Nervous system symptoms (which appear to be related to higher dosages of the drug, i.e., more than 500 mg daily)
Convulsions
Drowsiness and somnolence
Headache
Tremor
Dysarthria
Vertigo
Confusion and disorientation with loss of memory
Psychoses, possibly with suicidal tendencies
Character changes
Hyperirritability
Aggression
Paresis
Hyperreflexia
Paresthesia
Major and minor (localized) clonic seizures
Coma
Cardiovascular
Sudden development of congestive heart failure in patients receiving 1 to 1.5 g of Seromycin daily has been reported
Allergy (apparently not related to dosage)
Skin rash Miscellaneous
Elevated serum transaminase, especially in patients with preexisting liver disease
|
