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Septocaine (Articaine Hydrochloride / Epinephrine Bitartrate Subcutaneous) - Summary



(articaine hydrochloride 4% (40 mg/mL)
with epinephrine 1:100,000 injection)

Septocaine® injection is a sterile, aqueous solution that contains articaine HCl 4% (40mg/mL) with epinephrine bitartrate in a 1:100,000 strength.

Septocaine® is indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental and periodontal procedures.

See all Septocaine indications & dosage >>


Media Articles Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Study identifies characteristic EEG pattern of high-dose nitrous oxide anesthesia
Source: Pain / Anesthetics News From Medical News Today [2015.07.07]
While nitrous oxide gas has been used recreationally and medically for more than 200 years - originally for its euphoric and then for its pain relieving and anesthetic properties - the mechanism...

Surgery Patients Might Not Need Sedative Before Anesthesia
Source: MedicineNet lorazepam Specialty [2015.03.04]
Title: Surgery Patients Might Not Need Sedative Before Anesthesia
Category: Health News
Created: 3/3/2015 12:00:00 AM
Last Editorial Review: 3/4/2015 12:00:00 AM

Women With MCI Decline Twice as Fast as Men
Source: Medscape NeurologyHeadlines [2015.07.21]
Women with mild cognitive impairment decline twice as fast as men with MCI, and also have a much higher risk for cognitive problems after surgery and general anesthesia.
Medscape Medical News

For children with autism, trips to the dentist just got easier
Source: Dentistry News From Medical News Today [2015.05.14]
Adjusting the environment to be more soothing could eliminate the need for general anesthesia to cope with routine cleaningsGoing to the dentist might have just gotten a little less scary for the...

more news >>

Published Studies Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Comparison of injection pain of articaine and lidocaine in eyelid surgery. [2009.01]
PURPOSE: To compare the pain induced by tissue infiltration of lidocaine 2% with epinephrine 1:100,000 versus articaine 4% with epinephrine 1:100,000 for eyelid surgery... CONCLUSIONS: In this study, infiltration of articaine was less painful than lidocaine for eyelid surgery, making articaine an attractive alternative for local anesthesia.

The incidence of adverse reactions following 4% septocaine (articaine) in children. [2008.09]
PURPOSE: The purpose of this study was to report the incidence of adverse events following the use of 4% Septocaine in children... CONCLUSIONS: Since prolonged numbness appears to be the most frequent adverse event and occurred primarily in children younger than 7 years old, parents need to be informed and reassured accordingly.

Allergic reaction caused by articaine. [2005.03]
We report the case of a 51-year-old woman who had an immediate skin reaction after subcutaneous administration of a local anesthetic (LA) composed of articaine and epinephrine before a dental procedure. The patient subsequently underwent further dental procedures without LA... Provocations with the remaining anesthetics of the amide group were not carried out due to the patient's refusal.

more studies >>

Clinical Trials Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Spinal Anesthesia With Articaine and Lidocaine for Outpatient Surgery. [Active, not recruiting]
The purpose of this study is to compare two short-acting local anesthetics, articaine and lidocaine, for spinal anesthesia in day-case surgery. The onset time of the sensory- and motor block, recovery time until discharge and complications will be studied.

Spinal Anesthesia With Articaine and Bupivacaine for Outpatient Lower Limb Surgery [Completed]
The purpose of the trial is to compare two local anesthetics, articaine and bupivacaine for outpatient lower limb surgery. Onset and recovery times of sensory and motor blockade will be compared.

Compare Subperiosteal and Loco-Regional Anesthesia in Posterior Mandible Dental Implant Installation [Not yet recruiting]
In patients that are going to receive a dental implant in the posterior mandible (distal from canine), does the subperiosteal anesthetic technique with Articaine 1: 100. 000 4 % Epinephrine compared to the loco-regional one, produces the same analgesia during surgery ?

Efficacy Study of Articaine Lozenge to Enhance the Procedural Compliance of the Adults Undergoing Gastroduodenoscopy [Recruiting]

Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart Surgery [Recruiting]
The purpose of this study is to examine the wound infusion of articaine for treatment of acute post-sternotomy pain in a placebo-controlled manner using a prospective and randomized design and an active control (bupivacaine)

more trials >>

Reports of Suspected Septocaine (Articaine / Epinephrine Subcutaneous) Side Effects

Dyspnoea (15)Atelectasis (12)Dental Plaque (12)Device Related Infection (12)Multiple Myeloma (12)Pyrexia (12)Sedation (12)Tooth Discolouration (12)Hypoxia (12)Intervertebral Disc Degeneration (12)more >>

Page last updated: 2015-07-21

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