Septocaine (Articaine Hydrochloride / Epinephrine Bitartrate Subcutaneous) - Summary

SEPTOCAINE SUMMARY

Septocaine^®
(articaine hydrochloride 4% (40 mg/mL)
with epinephrine 1:100,000 injection)

Septocaine^® injection is a sterile, aqueous solution that contains articaine HCl 4% (40mg/mL) with epinephrine bitartrate in a 1:100,000 strength.

Septocaine^® is indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental and periodontal procedures.

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NEWS HIGHLIGHTS

Media Articles Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Abdominal Surgery Without General Anesthesia
Source: GastroIntestinal / Gastroenterology News From Medical News Today [2009.11.04]
A recent review in Faculty of 1000 Medicine Reports, a publication in which clinicians highlight advances in medical practice, suggests regional pain relief could be used during abdominal surgery. In this review, Michael Schaefer recommends a new approach that can be performed without the need for general anaesthetics.

Anesthesia, Exertional Heat Deaths May Be Linked
Source: MedicineNet Hyperthermia Specialty [2009.10.26]
Title: Anesthesia, Exertional Heat Deaths May Be Linked
Category: Health News
Created: 10/23/2009 4:10:00 PM
Last Editorial Review: 10/26/2009

Anesthesia in Youngest Kids May be Linked to Learning Disabilities
Source: MedicineNet Hernia Specialty [2009.03.25]
Title: Anesthesia in Youngest Kids May be Linked to Learning Disabilities
Category: Health News
Created: 3/25/2009 2:00:00 AM
Last Editorial Review: 3/25/2009

Need For Emergency Airway Surgery For Hard-to-Intubate Patients Reduced
Source: Respiratory / Asthma News From Medical News Today [2009.11.18]
Be prepared, that old Boy Scout motto, is being applied with great success to operating room patients whose anatomy may make it difficult for physicians to help them breathe during surgery, Johns Hopkins researchers report in a new study. When patients undergo general anesthesia, they stop breathing on their own and anesthesiologists must quickly insert a tube into the airway as a first step in machine-assisted breathing.

New Technique For Injectable Facial Fillers Improves Comfort, Recovery
Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today [2009.10.29]
Less pain during injections for wrinkle-fighting facial fillers. Less swelling afterward. Less time in the office waiting for anesthesia to take effect. These and other benefits of a new injection technique that UT Southwestern Medical Center plastic surgeons are helping pioneer are outlined in the October issue of Plastic and Reconstructive Surgery.

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Published Studies Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Comparison of injection pain of articaine and lidocaine in eyelid surgery. [2009.01]
PURPOSE: To compare the pain induced by tissue infiltration of lidocaine 2% with epinephrine 1:100,000 versus articaine 4% with epinephrine 1:100,000 for eyelid surgery... CONCLUSIONS: In this study, infiltration of articaine was less painful than lidocaine for eyelid surgery, making articaine an attractive alternative for local anesthesia.

The incidence of adverse reactions following 4% septocaine (articaine) in children. [2008.09]
PURPOSE: The purpose of this study was to report the incidence of adverse events following the use of 4% Septocaine in children... CONCLUSIONS: Since prolonged numbness appears to be the most frequent adverse event and occurred primarily in children younger than 7 years old, parents need to be informed and reassured accordingly.

Allergic reaction caused by articaine. [2005.03]
We report the case of a 51-year-old woman who had an immediate skin reaction after subcutaneous administration of a local anesthetic (LA) composed of articaine and epinephrine before a dental procedure. The patient subsequently underwent further dental procedures without LA... Provocations with the remaining anesthetics of the amide group were not carried out due to the patient's refusal.

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Clinical Trials Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Spinal Anesthesia With Articaine and Lidocaine for Outpatient Surgery. [Active, not recruiting]
The purpose of this study is to compare two short-acting local anesthetics, articaine and lidocaine, for spinal anesthesia in day-case surgery. The onset time of the sensory- and motor block, recovery time until discharge and complications will be studied.

Spinal Anesthesia With Articaine and Bupivacaine for Outpatient Lower Limb Surgery [Completed]
The purpose of the trial is to compare two local anesthetics, articaine and bupivacaine for outpatient lower limb surgery. Onset and recovery times of sensory and motor blockade will be compared.

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