(articaine hydrochloride 4% (40 mg/mL)
with epinephrine 1:100,000 injection)
Septocaine® injection is a sterile, aqueous solution that contains articaine HCl 4% (40mg/mL) with epinephrine bitartrate in a 1:100,000 strength.
Septocaine® is indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental and periodontal procedures.
Media Articles Related to Septocaine (Articaine / Epinephrine Subcutaneous)
FDA Issues Class 1 Recall of Defective Anesthesia Products
Source: Medscape Anesthesiology Headlines [2013.11.26]
The US FDA has issued a Class 1 Recall of anesthesia products that provide respiratory support to patients due to a potential defect that may cause serious adverse health concerns, including death.
Anesthesia Technique May Affect Survival After Breast Cancer Surgery: Study
Source: MedicineNet Breast Specialty [2013.10.15]
Title: Anesthesia Technique May Affect Survival After Breast Cancer Surgery: Study
Category: OnHealth Staging
Created: 10/15/2013 4:36:00 PM
Last Editorial Review: 10/15/2013 4:35:43 PM
Anesthesia May Harm Children's Brains
Source: MedicineNet Ear Tubes Specialty [2012.08.20]
Title: Anesthesia May Harm Children's Brains
Category: Health News
Created: 8/20/2012 11:00:00 AM
Last Editorial Review: 8/20/2012 12:00:00 AM
The effect of propofol on the sciatic nerve
Source: Pain / Anesthetics News From Medical News Today [2013.11.05]
Propofol is a rapid, but short-acting, intravenous drug that is preferentially used for the induction and maintenance of anesthesia. Propofol can inhibit inflammation and suppress the secretion of the proinflammatory cytokines interleukin-1, interleukin-6 and tumor necrosis factor alpha from astrocytes, and enhance the synthesis and release of the anti-inflammatory cytokine interleukin-10.
Local anesthetic injected in neck reduces severe hot flashes
Source: Pain / Anesthetics News From Medical News Today [2013.11.04]
A shot in the neck of local anesthesia may reduce hot flashes by as much as 50 percent for at least six months, a recent Northwestern Medicine® study found.
Published Studies Related to Septocaine (Articaine / Epinephrine Subcutaneous)
Comparison of injection pain of articaine and lidocaine in eyelid surgery. [2009.01]
PURPOSE: To compare the pain induced by tissue infiltration of lidocaine 2% with epinephrine 1:100,000 versus articaine 4% with epinephrine 1:100,000 for eyelid surgery... CONCLUSIONS: In this study, infiltration of articaine was less painful than lidocaine for eyelid surgery, making articaine an attractive alternative for local anesthesia.
The incidence of adverse reactions following 4% septocaine (articaine) in children. [2008.09]
PURPOSE: The purpose of this study was to report the incidence of adverse events following the use of 4% Septocaine in children... CONCLUSIONS: Since prolonged numbness appears to be the most frequent adverse event and occurred primarily in children younger than 7 years old, parents need to be informed and reassured accordingly.
Allergic reaction caused by articaine. [2005.03]
We report the case of a 51-year-old woman who had an immediate skin reaction after subcutaneous administration of a local anesthetic (LA) composed of articaine and epinephrine before a dental procedure. The patient subsequently underwent further dental procedures without LA... Provocations with the remaining anesthetics of the amide group were not carried out due to the patient's refusal.
Clinical Trials Related to Septocaine (Articaine / Epinephrine Subcutaneous)
Spinal Anesthesia With Articaine and Lidocaine for Outpatient Surgery. [Active, not recruiting]
The purpose of this study is to compare two short-acting local anesthetics, articaine and
lidocaine, for spinal anesthesia in day-case surgery. The onset time of the sensory- and
motor block, recovery time until discharge and complications will be studied.
Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart Surgery [Recruiting]
The purpose of this study is to examine the wound infusion of articaine for treatment of
acute post-sternotomy pain in a placebo-controlled manner using a prospective and randomized
design and an active control (bupivacaine)
Spinal Anesthesia With Articaine and Bupivacaine for Outpatient Lower Limb Surgery [Completed]
The purpose of the trial is to compare two local anesthetics, articaine and bupivacaine for
outpatient lower limb surgery. Onset and recovery times of sensory and motor blockade will be
Reports of Suspected Septocaine (Articaine / Epinephrine Subcutaneous) Side Effects
Dental Plaque (12),
Device Related Infection (12),
Multiple Myeloma (12),
Tooth Discolouration (12),
Intervertebral Disc Degeneration (12), more >>