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Septocaine (Articaine Hydrochloride / Epinephrine Bitartrate Subcutaneous) - Summary



(articaine hydrochloride 4% (40 mg/mL)
with epinephrine 1:100,000 injection)

Septocaine® injection is a sterile, aqueous solution that contains articaine HCl 4% (40mg/mL) with epinephrine bitartrate in a 1:100,000 strength.

Septocaine® is indicated for local, infiltrative, or conductive anesthesia in both simple and complex dental and periodontal procedures.

See all Septocaine indications & dosage >>


Media Articles Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Stimulating a specific brain pathway may induce active emergence from anesthesia
Source: Neurology / Neuroscience News From Medical News Today [2014.07.24]
Researchers may be one step closer to better understanding how anesthesia works.

Study finds low hand hygiene compliance rates during anesthesia administration
Source: Pain / Anesthetics News From Medical News Today [2014.07.02]
Anesthesia providers are missing opportunities to clean their hands during surgical procedures, according to a study published in the American Journal of Infection Control, the official publication...

Use of regional anesthesia during hip fracture surgery not associated with lower risk of death
Source: Pain / Anesthetics News From Medical News Today [2014.06.24]
Among more than 56,000 adults undergoing hip repair between 2004 and 2011, the use of regional anesthesia compared with general anesthesia was not associated with a lower risk of death at 30 days...

Anesthesia May Harm Children's Brains
Source: MedicineNet Ear Tubes Specialty [2012.08.20]
Title: Anesthesia May Harm Children's Brains
Category: Health News
Created: 8/20/2012 11:00:00 AM
Last Editorial Review: 8/20/2012 12:00:00 AM

Hydroxyethyl starch in resuscitation fluid has direct harmful effects on kidney cells
Source: Urology / Nephrology News From Medical News Today [2014.07.14]
The increased risk of kidney injury related to the use of hydroxyethyl starch (HES) in resuscitation fluids reflects the mass of HES molecules, according to a report in Anesthesia & Analgesia...

more news >>

Published Studies Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Comparison of injection pain of articaine and lidocaine in eyelid surgery. [2009.01]
PURPOSE: To compare the pain induced by tissue infiltration of lidocaine 2% with epinephrine 1:100,000 versus articaine 4% with epinephrine 1:100,000 for eyelid surgery... CONCLUSIONS: In this study, infiltration of articaine was less painful than lidocaine for eyelid surgery, making articaine an attractive alternative for local anesthesia.

The incidence of adverse reactions following 4% septocaine (articaine) in children. [2008.09]
PURPOSE: The purpose of this study was to report the incidence of adverse events following the use of 4% Septocaine in children... CONCLUSIONS: Since prolonged numbness appears to be the most frequent adverse event and occurred primarily in children younger than 7 years old, parents need to be informed and reassured accordingly.

Allergic reaction caused by articaine. [2005.03]
We report the case of a 51-year-old woman who had an immediate skin reaction after subcutaneous administration of a local anesthetic (LA) composed of articaine and epinephrine before a dental procedure. The patient subsequently underwent further dental procedures without LA... Provocations with the remaining anesthetics of the amide group were not carried out due to the patient's refusal.

more studies >>

Clinical Trials Related to Septocaine (Articaine / Epinephrine Subcutaneous)

Spinal Anesthesia With Articaine and Lidocaine for Outpatient Surgery. [Active, not recruiting]
The purpose of this study is to compare two short-acting local anesthetics, articaine and lidocaine, for spinal anesthesia in day-case surgery. The onset time of the sensory- and motor block, recovery time until discharge and complications will be studied.

Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart Surgery [Recruiting]
The purpose of this study is to examine the wound infusion of articaine for treatment of acute post-sternotomy pain in a placebo-controlled manner using a prospective and randomized design and an active control (bupivacaine)

Spinal Anesthesia With Articaine and Bupivacaine for Outpatient Lower Limb Surgery [Completed]
The purpose of the trial is to compare two local anesthetics, articaine and bupivacaine for outpatient lower limb surgery. Onset and recovery times of sensory and motor blockade will be compared.

more trials >>

Reports of Suspected Septocaine (Articaine / Epinephrine Subcutaneous) Side Effects

Dyspnoea (15)Atelectasis (12)Dental Plaque (12)Device Related Infection (12)Multiple Myeloma (12)Pyrexia (12)Sedation (12)Tooth Discolouration (12)Hypoxia (12)Intervertebral Disc Degeneration (12)more >>

Page last updated: 2014-07-24

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