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Sedapap (Butalbital / Acetaminophen) - Summary



Butalbital and acetaminophen is supplied in tablet form for oral administration.

Butalbital and Acetaminophen Tablets are indicated for the relief of the symptom complex of tension (or muscle contraction) headache.

Evidence supporting the efficacy and safety of this combination product in the treatment of multiple recurrent headaches is unavailable. Caution in this regard is required because butalbital is habit-forming and potentially abusable.

See all Sedapap indications & dosage >>


Media Articles Related to Sedapap (Butalbital / Acetaminophen)

New Headache Diagnostic Criteria Will Coordinate with ICD-11
Source: Medscape Anesthesiology Headlines [2017.09.11]
The new International Classification of Headache Disorders-3, now under development, will allow more consistent diagnoses and better clinical trials, as well as coordinating with ICD-11.
Medscape Medical News

Source: MedicineNet Anthrax Specialty [2017.08.16]
Title: Headache
Category: Diseases and Conditions
Created: 5/31/2002 12:00:00 AM
Last Editorial Review: 8/16/2017 12:00:00 AM

Migraine vs. Headache: Differences and Similarities
Source: MedicineNet Facial Nerve Problems Specialty [2017.06.26]
Title: Migraine vs. Headache: Differences and Similarities
Category: Diseases and Conditions
Created: 6/21/2017 12:00:00 AM
Last Editorial Review: 6/26/2017 12:00:00 AM

Migraine Headache
Source: MedicineNet Antiphospholipid Syndrome Specialty [2017.03.13]
Title: Migraine Headache
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/13/2017 12:00:00 AM

Cluster Headaches
Source: MedicineNet Cauliflower Ear Specialty [2016.08.25]
Title: Cluster Headaches
Category: Diseases and Conditions
Created: 2/4/2005 12:00:00 AM
Last Editorial Review: 8/25/2016 12:00:00 AM

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Published Studies Related to Sedapap (Butalbital / Acetaminophen)

Sumatriptan-Naproxen and Butalbital: A Double-Blind, Placebo-Controlled Crossover Study. [2011.11.21]
Objectives.- The primary objective was to compare the efficacy of a sumatriptan and naproxen combination medication (SumaRT/Nap-85 mg sumatriptan and 500 mg naproxen sodium), a butalbital-containing combination medication (BCM-50 mg butalbital, 325 mg acetaminophen, 40 mg caffeine), and placebo when used to treat moderate to severe migraine headache pain in subjects who used BCMs in the past.

Butalbital in the treatment of headache: history, pharmacology, and efficacy. [2001.11]
Analgesics containing butalbital compounded with aspirin, acetaminophen, and/or caffeine are widely used for the treatment of migraine and tension-type headache. The butalbital-containing compounds are efficacious in placebo-controlled trials among patients with episodic tension-type headaches.Because of concerns about overuse, medication-overuse headache, and withdrawal, their use should be limited and carefully monitored.

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Page last updated: 2017-09-11

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