SECONAL SUMMARY
SECONAL SODIUM
SECOBARBITAL SODIUM CAPSULES
CII
Rx only
The barbiturates are nonselective central nervous system (CNS) depressants that are primarily used as sedative hypnotics. In subhypnotic doses, they are also used as anticonvulsants. The barbiturates and their sodium salts are subject to control under the Federal Controlled Substances Act. Seconal Sodium® (Secobarbital Sodium Capsules, USP) is a barbituric acid derivative and occurs as a white, odorless, bitter powder that is very soluble in water, soluble in alcohol, and practically insoluble in ether.
Seconal (secobarbital) is indicated for the following:
A. Hypnotic, for the short-term treatment of insomnia, since it appears to lose its effectiveness for sleep induction and sleep maintenance after 2 weeks (see Clinical Pharmacology).
B. Preanesthetic
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NEWS HIGHLIGHTSMedia Articles Related to Seconal (Secobarbital)
Making Sense Of The Neurobiology Of Restless Legs Syndrome And Related Insomnia
Source: Neurology / Neuroscience News From Medical News Today [2013.05.09]
Johns Hopkins researchers believe they may have discovered an explanation for the sleepless nights associated with restless legs syndrome (RLS), a symptom that persists even when the disruptive, overwhelming nocturnal urge to move the legs is treated successfully with medication...
Insomnia May Raise Risk of Heart Attack, Stroke
Source: MedicineNet Hyperthyroidism Specialty [2012.11.05]
Title: Insomnia May Raise Risk of Heart Attack, Stroke
Category: Health News
Created: 11/4/2012 8:35:00 PM
Last Editorial Review: 11/5/2012 12:00:00 AM
Insomnia Pictures Slideshow: 10 Tips to Avoid Insomnia
Source: MedicineNet Sleep Aids And Stimulants Specialty [2012.08.22]
Title: Insomnia Pictures Slideshow: 10 Tips to Avoid Insomnia
Category: Slideshows
Created: 12/10/2008 12:00:00 AM
Last Editorial Review: 8/22/2012 12:00:00 AM
10 Tips to Avoid Insomnia and Get a Good Night's Sleep
Source: MedicineNet Sleep Aids And Stimulants Specialty [2012.08.07]
Title: 10 Tips to Avoid Insomnia and Get a Good Night's Sleep
Category: Doctor's Views
Created: 6/14/2005 12:00:00 AM
Last Editorial Review: 8/7/2012 12:00:00 AM
Insomnia
Source: MedicineNet Rabies Specialty [2012.03.06]
Title: Insomnia
Category: Symptoms and Signs
Created: 7/28/2006 12:00:00 AM
Last Editorial Review: 3/6/2012 12:00:00 AM
Published Studies Related to Seconal (Secobarbital)
Postdischarge secobarbital after ED migraine treatment decreases pain and improves resolution. [2011.01]
OBJECTIVE: The objective of the study was to determine whether the addition of postdischarge oral secobarbital to standard emergency department (ED) migraine headache therapy improves pain relief and headache resolution compared with placebo. SETTING: The setting is an urban ED with 70 000 yearly visits... CONCLUSIONS: Addition of postdischarge oral secobarbital to a standard ED migraine treatment regimen decreased headache pain at 24 hours after discharge and improved the rate of headache resolution compared with placebo. Published by Elsevier Inc.
Postdischarge secobarbital after ED migraine treatment decreases pain and
improves resolution. [2011]
SETTING: The setting is an urban ED with 70 000 yearly visits... CONCLUSIONS: Addition of postdischarge oral secobarbital to a standard ED
Postdischarge secobarbital after ED migraine treatment decreases pain and improves resolution. [2010.03.25]
OBJECTIVE: The objective of the study was to determine whether the addition of postdischarge oral secobarbital to standard emergency department (ED) migraine headache therapy improves pain relief and headache resolution compared with placebo. SETTING: The setting is an urban ED with 70 000 yearly visits... CONCLUSIONS: Addition of postdischarge oral secobarbital to a standard ED migraine treatment regimen decreased headache pain at 24 hours after discharge and improved the rate of headache resolution compared with placebo. Published by Elsevier Inc.
Comparative drug effects and abuse liability of lorazepam, buspirone, and secobarbital in nondependent subjects. [1992.04]
The pharmacologic effects of lorazepam (2 mg), buspirone (20 mg, 10 mg), secobarbital (100 mg), and placebo were compared in 15 male, experienced, intermittent nontherapeutic drug users. All drugs produced a "drug effect," however, buspirone 20 mg was significantly less liked than were lorazepam, secobarbital, or buspirone 10 mg (p less than .05) but not placebo...
Alcohol and secobarbital effects as a function of familial alcoholism: extended intoxication and increased withdrawal effects. [1991.02]
Response differences following administration of alcohol between adult males with a positive (FHP) versus negative (FHN) family history of alcoholism have been demonstrated in previous research and are thought to be related to risk for developing alcoholism... FHP subjects reported more extended intoxication and greater withdrawal effects following both ethanol and the high dose of secobarbital than did FHN subjects.(ABSTRACT TRUNCATED AT 250 WORDS).
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