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Seconal (Secobarbital Sodium) - Summary

 
 



SECONAL SUMMARY

The barbiturates are nonselective central nervous system (CNS) depressants that are primarily used as sedative hypnotics. In subhypnotic doses, they are also used as anticonvulsants. The barbiturates and their sodium salts are subject to control under the Federal Controlled Substances Act. Seconal Sodium® (Secobarbital Sodium Capsules, USP) is a barbituric acid derivative and occurs as a white, odorless, bitter powder that is very soluble in water, soluble in alcohol, and practically insoluble in ether.

SECONAL (SECOBARBITAL) is indicated for the following:

  1. Hypnotic, for the short-term treatment of insomnia, since it appears to lose its effectiveness for sleep induction and sleep maintenance after 2 weeks (see Clinical Pharmacology).
  2. Preanesthetic

See all Seconal indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Seconal (Secobarbital)

Insomnia Quiz: What Is Insomnia?
Source: MedicineNet Sleep Specialty [2017.09.19]
Title: Insomnia Quiz: What Is Insomnia?
Category: MedicineNet Quiz
Created: 6/6/2016 12:00:00 AM
Last Editorial Review: 9/19/2017 6:44:12 PM

20 Tips to Beat Insomnia and Sleep Better
Source: MedicineNet Sleep Aids And Stimulants Specialty [2017.07.26]
Title: 20 Tips to Beat Insomnia and Sleep Better
Category: Slideshows
Created: 10/1/2014 12:00:00 AM
Last Editorial Review: 7/26/2017 12:00:00 AM

Insomnia
Source: MedicineNet Hyperthyroidism Specialty [2017.05.12]
Title: Insomnia
Category: Symptoms and Signs
Created: 7/28/2006 12:00:00 AM
Last Editorial Review: 5/12/2017 12:00:00 AM

Insomnia (Symptoms, Causes, Remedies, and Cures)
Source: MedicineNet Biorhythms Specialty [2017.04.19]
Title: Insomnia (Symptoms, Causes, Remedies, and Cures)
Category: Diseases and Conditions
Created: 6/6/2005 12:00:00 AM
Last Editorial Review: 4/19/2017 12:00:00 AM

Sleep Disorders: Insomnia, Sleep Apnea, and More
Source: MedicineNet modafinil Specialty [2016.08.22]
Title: Sleep Disorders: Insomnia, Sleep Apnea, and More
Category: Slideshows
Created: 7/23/2010 2:39:00 PM
Last Editorial Review: 8/22/2016 12:00:00 AM

more news >>

Published Studies Related to Seconal (Secobarbital)

Postdischarge secobarbital after ED migraine treatment decreases pain and improves resolution. [2011.01]
OBJECTIVE: The objective of the study was to determine whether the addition of postdischarge oral secobarbital to standard emergency department (ED) migraine headache therapy improves pain relief and headache resolution compared with placebo. SETTING: The setting is an urban ED with 70 000 yearly visits... CONCLUSIONS: Addition of postdischarge oral secobarbital to a standard ED migraine treatment regimen decreased headache pain at 24 hours after discharge and improved the rate of headache resolution compared with placebo. Published by Elsevier Inc.

Postdischarge secobarbital after ED migraine treatment decreases pain and improves resolution. [2011]
SETTING: The setting is an urban ED with 70 000 yearly visits... CONCLUSIONS: Addition of postdischarge oral secobarbital to a standard ED

Postdischarge secobarbital after ED migraine treatment decreases pain and improves resolution. [2010.03.25]
OBJECTIVE: The objective of the study was to determine whether the addition of postdischarge oral secobarbital to standard emergency department (ED) migraine headache therapy improves pain relief and headache resolution compared with placebo. SETTING: The setting is an urban ED with 70 000 yearly visits... CONCLUSIONS: Addition of postdischarge oral secobarbital to a standard ED migraine treatment regimen decreased headache pain at 24 hours after discharge and improved the rate of headache resolution compared with placebo. Published by Elsevier Inc.

Comparative drug effects and abuse liability of lorazepam, buspirone, and secobarbital in nondependent subjects. [1992.04]
The pharmacologic effects of lorazepam (2 mg), buspirone (20 mg, 10 mg), secobarbital (100 mg), and placebo were compared in 15 male, experienced, intermittent nontherapeutic drug users. All drugs produced a "drug effect," however, buspirone 20 mg was significantly less liked than were lorazepam, secobarbital, or buspirone 10 mg (p less than .05) but not placebo...

Alcohol and secobarbital effects as a function of familial alcoholism: extended intoxication and increased withdrawal effects. [1991.02]
Response differences following administration of alcohol between adult males with a positive (FHP) versus negative (FHN) family history of alcoholism have been demonstrated in previous research and are thought to be related to risk for developing alcoholism... FHP subjects reported more extended intoxication and greater withdrawal effects following both ethanol and the high dose of secobarbital than did FHN subjects.(ABSTRACT TRUNCATED AT 250 WORDS).

more studies >>

Clinical Trials Related to Seconal (Secobarbital)

Effects of Hallucinogens and Other Drugs on Mood and Performance [Recruiting]
This non-treatment study will investigate the effects on mood and performance caused by hallucinogens and other psychoactive compounds.

more trials >>


Page last updated: 2017-09-19

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