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Seasonale (Levonorgestrel / Ethinyl Estradiol) - Drug Interactions, Contraindications, Overdosage

 


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8. DRUG INTERACTIONS

OVERDOSAGE

Serious ill effects have not been reported following acute ingestion of large doses of oral contraceptives by young children. Overdosage may cause nausea, and withdrawal bleeding may occur in females.

NONCONTRACEPTIVE HEALTH BENEFITS

The following noncontraceptive health benefits related to the use of oral contraceptives are supported by epidemiological studies which largely utilized oral contraceptive formulations containing doses exceeding 0.035 mg of ethinyl estradiol or 0.05 mg of mestranol.

Effects on menses:

  • May decrease blood loss and may decrease incidence of iron-deficiency anemia
  • May decrease incidence of dysmenorrhea

Effects related to inhibition of ovulation:

  • May decrease incidence of functional ovarian cysts
  • May decrease incidence of ectopic pregnancies

Effects from long-term use:

  • May decrease incidence of fibroadenomas and fibrocystic disease of the breast
  • May decrease incidence of acute pelvic inflammatory disease
  • May decrease incidence of endometrial cancer
  • May decrease incidence of ovarian cancer

OVERDOSAGE

Serious ill effects have not been reported following ingestion of large doses of oral contraceptives by young children. Overdosage may cause nausea and withdrawal bleeding in females. In case of overdosage, contact your healthcare provider or pharmacist.

CONTRAINDICATIONS

Oral contraceptives should not be used in women who currently have the following conditions:

  • Thrombophlebitis or thromboembolic disorders
  • A past history of deep vein thrombophlebitis or thromboembolic disorders
  • Cerebrovascular or coronary artery disease (current or history)
  • Valvular heart disease with thrombogenic complications
  • Uncontrolled hypertension
  • Diabetes with vascular involvement
  • Headaches with focal neurological symptoms
  • Major surgery with prolonged immobilization
  • Known or suspected carcinoma of the breast or personal history of breast cancer
  • Carcinoma of the endometrium or other known or suspected estrogen-dependent neoplasia
  • Undiagnosed abnormal genital bleeding
  • Cholestatic jaundice of pregnancy or jaundice with prior pill use
  • Hepatic adenomas or carcinomas, or active liver disease
  • Known or suspected pregnancy
  • Hypersensitivity to any component of this product

Page last updated: 2006-01-13

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