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Scopolamine (Scopolamine Hydrobromide) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

With nearly all antimuscarinic drugs, dry mouth is the first and dry skin is the second most common side effect.  Thirst and difficulty in swallowing occur when the mouth and esophagus become sufficiently dry; chronic dry mouth also fosters dental caries.  Suppression of sweating causes reflexive flushing and heat intolerance and can result in heat exhaustion or heat stroke in a hot environment; it also contributes to the hyperthermia seen in intoxication.  Mydriasis frequently occurs, especially with scopolamine; photophobia and blurring of vision are consequences of mydriasis.  Cycloplegia (which exacerbates blurred vision) occurs approximately concomitantly with mydriasis, but usually higher doses are required.  In susceptible persons, especially the elderly, cycloplegia may contribute to an elevation of intraocular pressure.  Difficulty in urination and urinary retention may occur.  Tachycardia is a common side effect.  Constipation, even bowel stasis, may occur.

In the larger therapeutic doses, scopolamine may cause dizziness, restlessness, tremors, fatigue and locomotor difficulties.



REPORTS OF SUSPECTED SCOPOLAMINE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Scopolamine. The information is not vetted and should not be considered as verified clinical evidence.

Possible Scopolamine side effects / adverse reactions in 13 year old male

Reported by a physician from United States on 2011-10-10

Patient: 13 year old male weighing 39.6 kg (87.1 pounds)

Reactions: Anxiety, Confusional State, Akathisia, Pruritus, Pain, Chills, Anger, Memory Impairment, Paraesthesia

Suspect drug(s):
Methotrexate
    Indication: Precursor B-Lymphoblastic Lymphoma
    Start date: 2011-09-08

Pegaspargase
    Indication: Precursor B-Lymphoblastic Lymphoma
    Start date: 2011-09-08

Zofran
    Indication: Product Used FOR Unknown Indication

Vincristine
    Dosage: 1.5mgm2 cyclic
    Indication: Precursor B-Lymphoblastic Lymphoma
    Start date: 2011-09-08

Bactrim
    Indication: Product Used FOR Unknown Indication

Ranitidine
    Indication: Product Used FOR Unknown Indication

Prednisone
    Dosage: 20mgm2 cyclic
    Administration route: Oral
    Indication: Precursor B-Lymphoblastic Lymphoma
    Start date: 2011-09-08

Benadryl
    Indication: Product Used FOR Unknown Indication

Cytarabine
    Indication: Precursor B-Lymphoblastic Lymphoma

Hydrocortisone
    Indication: Precursor B-Lymphoblastic Lymphoma
    Start date: 2011-09-08

Ativan
    Indication: Product Used FOR Unknown Indication

Velcade
    Dosage: 1.3mgm2 cyclic
    Indication: Precursor B-Lymphoblastic Lymphoma
    Start date: 2011-09-08

Doxorubicin HCL
    Dosage: 60mgm2 cyclic
    Indication: Precursor B-Lymphoblastic Lymphoma
    Start date: 2011-09-08

Scopolamine
    Indication: Product Used FOR Unknown Indication



Possible Scopolamine side effects / adverse reactions in 44 year old male

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2011-10-26

Patient: 44 year old male weighing 74.4 kg (163.7 pounds)

Reactions: White Blood Cell Count Decreased, Weight Decreased, Vomiting, Persecutory Delusion, Hallucination, Auditory, RED Blood Cell Target Cells Present, Microcytic Anaemia, RED Blood Cell Elliptocytes Present, Seasonal Allergy, Iron Deficiency Anaemia, Ideas of Reference, Platelet Count Decreased, Salivary Hypersecretion, Neutropenia

Suspect drug(s):
Scopolamine
    Dosage: 10 mg, oral
    Administration route: Oral
    Indication: Irritable Bowel Syndrome

Risperidone
    Indication: Product Used FOR Unknown Indication

Clozaril
    Dosage: 400 mg, oral
    Indication: Schizophrenia

Other drugs received by patient: Ferrous Suphate (Ferrous Sulfate); Hyoscine Hydrobromide (Hyoscine Hydrobromide); Sertraline Hydrochloride



Possible Scopolamine side effects / adverse reactions in 16 year old male

Reported by a physician from United Kingdom on 2011-10-27

Patient: 16 year old male weighing 28.0 kg (61.6 pounds)

Reactions: Incorrect Route of Drug Administration, Vomiting, Wrong Technique in Drug Usage Process, Pruritus, Dyskinesia, Eructation, Food Aversion, OFF Label USE, Rash Erythematous, Application Site Irritation, Hypersomnia

Suspect drug(s):
Scopolamine
    Dosage: 1 df, q72h
    Indication: Salivary Hypersecretion
    Start date: 2011-05-16
    End date: 2011-09-16

Scopolamine
    Dosage: unk, unk
    Start date: 2002-01-01
    End date: 2002-01-01

Metoclopramide
    Dosage: 5 to 10mg, prn
    Indication: Vomiting
    Start date: 2011-09-05

Scopolamine
    Administration route: Oral
    Start date: 2011-09-16
    End date: 2011-09-16



See index of all Scopolamine side effect reports >>

Drug label data at the top of this Page last updated: 2012-08-30

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