Sclerosol (Talc Intrapleural) - Summary

SCLEROSOL SUMMARY

SCLEROSOL® INTRAPLEURAL AEROSOL
(sterile talc powder)
NDC No. 63256-100-30

Sclerosol® Intrapleural Aerosol (sterile talc powder 4 g) is a sclerosing agent for intrapleural administration supplied as a single-use, pressurized spray canister with two delivery tubes of 15 cm and 25 cm in length. Each canister contains 4.0 g of talc, either white or off-white to light grey, asbestos-free, and brucite-free grade of talc of controlled granulometry. The composition of the talc is ≥ 95% talc as hydrated magnesium silicate.

Sclerosol® Intrapleural Aerosol, administered by aerosol during thoracoscopy or open thoracotomy, is indicated to prevent recurrence of malignant pleural effusions in symptomatic patients.

SCLEROSOL NEWS HIGHLIGHTS

Published Studies Related to Sclerosol (Talc Intrapleural)

Pleural mesothelial cells mediate inflammatory and profibrotic responses in talc-induced pleurodesis. [2007.12]

Safety of pleurodesis with talc poudrage in malignant pleural effusion: a prospective cohort study. [2007.05.05]

The short-term administration of Ketoprofen does not decrease the effect of Pleurodesis induced by talc or Doxycycline in rabbits. [2007.05]

Comparison of pleurodesis by erythromycin, talc, doxycycline, and diazepam in a rabbit model. [2007.01]

Talc poudrage versus talc slurry in the treatment of malignant pleural effusion. A prospective comparative study. [2006.12]

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Clinical Trials Related to Sclerosol (Talc Intrapleural)

Bleomycin, Doxycycline, or Talc in Treating Patients With Malignant Pleural Effusions [Active, not recruiting]

A Comparative Study of the Safety and Efficacy of Face Talc Slurry and Iodopovidone for Pleurodesis [Recruiting]

Tunneled Pleural Catheter in Partially Entrapped Lung [Not yet recruiting]

Asthma Clinical Research Network (ACRN) Trial - Tiotropium Bromide as an Alternative to Increased Inhaled Corticosteroid in Patients Inadequately Controlled on a Lower Dose of Inhaled Corticosteroid (TALC) [Recruiting]

Standard Chest Tube Compared With a Small Catheter in Treating Malignant Pleural Effusion in Patients With Cancer [Recruiting]

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