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Scandonest (Mepivacaine Hydrochloride Subcutaneous) - Indications and Dosage

 
 



Indications and usage

SCANDONEST is indicated for production of local anesthesia for dental procedures by infiltration or nerve block in adults and children.

Dosage and administration

As with all local anesthetics the dose varies and depends upon the area to be anesthetized, the vascularity of the tissues, individual tolerance and the technique of anesthesia. The lowest dose needed to provide effective anesthesia should be administered. For specific techniques and procedures refer to standard dental manuals and textbooks.

For infiltration and block injections in the upper or lower jaw, the average dose of 1 cartridge will usually suffice.

Each cartridge contains 1.7 mL (34 mg of 2% or 51 mg of 3%).

5.3 cartridges (180 mg of the 2% solution or 270 mg of the 3% solution) are usually adequate to effect anesthesia of the entire oral cavity. Whenever a larger dose seems to be necessary for an extensive procedure, the maximum dose should be calculated accordlng to the patient's weight. A dose of up to 3 mg per pound of body weight may be administered. At any single dental sitting the total dose for all injected sites should not exceed 400 mg in adults.

The maximum pediatric dose should be carefully calculated:

Maxlmum Dose for pediatric population =
Child's Weight (lbs) × Maximum Recommended Dose
          150                          For Adults (400 mg)

The following table, approximating these calculations, may also be used as a guide. This table is based upon a recommended maximum for larger pediatric population of 5.3 cartridges (the maximum recommended adult dose) during any single dental sitting, regardless of the child's weight or (for 2 % mepivacaine) calculated maximum amount of drug:

Maximum Allowable Dosage
3% Mepivacaine
(Plain)
2% Mepivacaine
1:20,000 Levonordefrin
3 mg/lb
(270 mg max)
3 mg/lb
(180 mg max)
Weight
(lbs)
mgNumber of CartridgesmgNumber of Cartridges
  20  601.2  601.8
  30  901.8  902.6
  401202.31203.5
  501502.91504.4
  601803.51805.3
  802404.71805.3
1002705.31805.3
1202705.31805.3

Adapted from Malamed, Stanley F: Handbook of medical emergencies in the dental office, ed. 2, St Louis, 1982. The C V Mosby Co.

When using SCANDONEST for infiltration or regional block anesthesia, injection should always be made slowly and with frequent aspiration.

Any unused portion of a cartridge should be discarded.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

Disinfection of cartridges

As in the case of any cartridge, the diaphragm should be disinfected before needle puncture. The diaphragm should be thoroughly swabbed with either pure 91% isopropyl alcohol or 70% ethyl alcohol, USP just prior to use. Many commercially available alcohol solutions contain ingredients which are injurious to container components, and therefore, should not be used. Cartridges should not be immersed in any solution.

How supplied

- SCANDONEST 2% L (Mepivacaine Hydrochoride and Levonordefrin injection, USP), is available in cardboard boxes containing 5 blisters of 10 × 1.7 mL dental cartridges, 50 per cartons (NDC 12862-1097-8).

- SCANDONEST 3%Plain (Mepivacaine hydrochoride injection, USP), is available in cardboard boxes containing 5 blisters of 10 × 1.7 mL dental cartridges, 50 per cartons (NDC 12862-1098-9).

Store at room temperature, below 25°C (77°F). Protect from light. Do not permit to freeze.

CANS: For protection from light, retain in can until time of use. Once opened, the can should be reclosed using the plastic cap.

BOXES: For protection from light, retain in box until time of use. Once opened, the box should be reclosed by closing the top flap.

SCANDONEST 2%L should not be use if color is pinkish or darker than slightly yellow or if it contains a precipitate.

Cartridge warmers should not be used with SCANDONEST products.

10/04 (1)

Distributed in the U.S.A. by:
Septodont, Inc.
245 Quigley Boulevard - Suite C
NEW CASTLE, Delaware 19720 - U.S.A.

Made in France by:
SEPTODONT

® 05 14 117 90 00

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