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Sanctura XR (Trospium Chloride) - Published Studies

 
 



Sanctura XR Related Published Studies

Well-designed clinical trials related to Sanctura XR (Trospium)

Once-daily trospium chloride 60 mg extended release in subjects with overactive bladder syndrome who use multiple concomitant medications: Post hoc analysis of pooled data from two randomized, placebo-controlled trials. [2011.02.01]

Trospium chloride once-daily extended release is efficacious and tolerated in elderly subjects (aged >/= 75 years) with overactive bladder syndrome. [2011.02]

Safety and efficacy of once-daily trospium chloride extended-release in male patients with overactive bladder. [2011.01]

Once-daily trospium chloride 60 mg extended-release provides effective, long-term relief of overactive bladder syndrome symptoms. [2011]

Comparison of intravaginal electrical stimulation and trospium hydrochloride in women with overactive bladder syndrome: a randomized controlled study. [2010.04]

Obesity is associated with a more severe overactive bladder disease state that is effectively treated with once-daily administration of trospium chloride extended release. [2010.04]

Extended-release trospium chloride improves quality of life in overactive bladder. [2010.03]

Pharmacokinetics of once-daily trospium chloride 60 mg extended release and twice-daily trospium chloride 20 mg in healthy adults. [2010.02]

Extended-release trospium chloride improves quality of life in overactive bladder. [2010]

Trospium chloride extended release is effective and well tolerated in women with overactive bladder syndrome. [2009.12]

Trospium chloride and oxybutynin hydrochloride in a german study of adults with urinary urge incontinence: results of a 12-week, multicenter, randomized, double-blind, parallel-group, flexible-dose noninferiority trial. [2009.11]

Trospium 60 mg once daily (QD) for overactive bladder syndrome: results from a placebo-controlled interventional study. [2008.03]

Once daily trospium chloride is effective and well tolerated for the treatment of overactive bladder: results from a multicenter phase III trial. [2007.09]

Trospium chloride in patients with neurogenic detrusor overactivity: is dose titration of benefit to the patients? [2006.12]

Predictive power of an in vitro system to assess drug interactions of an antimuscarinic medication: a comparison of in vitro and in vivo drug-drug interaction studies of trospium chloride with digoxin. [2006.07]

Multicenter phase III trial studying trospium chloride in patients with overactive bladder. [2006.02]

Trospium chloride for the treatment of overactive bladder with urge incontinence. [2005.05]

Effect of trospium chloride on somnolence and sleepiness in patients with overactive bladder. [2004.12]

Trospium chloride improves overactive bladder symptoms: a multicenter phase III trial. [2004.06]

Trospium chloride for the treatment of detrusor instability in children. [2003.11]

Controlled, double-blind, multicentre clinical trial to investigate long-term tolerability and efficacy of trospium chloride in patients with detrusor instability. [2003.05]

Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous system. [2001.06]

Efficacy of trospium chloride in patients with detrusor instability: a placebo-controlled, randomized, double-blind, multicentre clinical trial. [2000.04]

Bioavailability of trospium chloride after intravesical instillation in patients with neurogenic lower urinary tract dysfunction: A pilot study. [1999]

Effects of two anticholinergic drugs, trospium chloride and biperiden, on motility and evoked potentials of the oesophagus. [1998.10]

[Intravesical instillation of trospium chloride, oxybutynin and verapamil for relaxation of the bladder detrusor muscle. A placebo controlled, randomized clinical test] [1998.05]

Trospium chloride versus oxybutynin: a randomized, double-blind, multicentre trial in the treatment of detrusor hyper-reflexia. [1995.04]

Effect of the quaternary ammonium compound trospium chloride on 24 hour jejunal motility in healthy subjects. [1994.01]

Safety and tolerance of trospium chloride in the high dose range. [1993.04]

The effect of trospium chloride on oesophageal motility. [1993.02]

Ultrasound studies of the effect of trospium chloride on gall-bladder kinetics. [1992.12]

Effect of trospium chloride on urodynamic parameters in patients with detrusor hyperreflexia due to spinal cord injuries. A multicentre placebo-controlled double-blind trial. [1991]

Well-designed clinical trials possibly related to Sanctura XR (Trospium)

Anticholinergic therapy vs. onabotulinumtoxina for urgency urinary incontinence. [2012]

Systematic review and meta-analysis: do clinical trials testing antimuscarinic agents for overactive bladder adequately measure central nervous system adverse events? [2011.07]

Comparison of different treatment protocols in the treatment of idiopathic detrusor overactivity: a randomized controlled trial. [2011.04]

Effective treatment of neurogenic detrusor dysfunction by combined high-dosed antimuscarinics without increased side-effects. [2008.05]

Time to onset of improvement in symptoms of overactive bladder using antimuscarinic treatment. [2006.03]

The overactive bladder-symptom composite score: a composite symptom score of toilet voids, urgency severity and urge urinary incontinence in patients with overactive bladder. [2005.05]

Effects on sleep of anticholinergics used for overactive bladder treatment in healthy volunteers aged > or = 50 years. [2005.02]

Other research related to Sanctura XR (Trospium)

Once-daily trospium chloride 60 mg extended-release provides effective, long-term relief of overactive bladder syndrome symptoms. [2011.09]

Once-daily administration of trospium chloride extended release provides 24-hr coverage of nocturnal and diurnal symptoms of overactive bladder: an integrated analysis of two phase III trials. [2011.04]

Dose escalation improves therapeutic outcome: post hoc analysis of data from a 12-week, multicentre, double-blind, parallel-group trial of trospium chloride in patients with urinary urge incontinence. [2010.09.14]

Trospium chloride once-daily extended release is efficacious and tolerated in elderly subjects (aged >/=75 years) with overactive bladder syndrome. [2010.08.06]

Trospium chloride has no effect on memory testing and is assay undetectable in the central nervous system of older patients with overactive bladder. [2010.08]

Effects of combined use of trospium chloride and melatonin on in vitro contractility of rat urinary bladder. [2010.04]

Obesity is associated with a more severe overactive bladder disease state that is effectively treated with once-daily administration of trospium chloride extended release. [2010]

New once-daily formulation for trospium in overactive bladder. [2010]

Comparison of intravaginal electrical stimulation and trospium hydrochloride in women with overactive bladder syndrome: a randomized controlled study. [2010]

Pharmacokinetics of once-daily trospium chloride 60 mg extended release and twice-daily trospium chloride 20 mg in healthy adults. [2010]

Trospium chloride once-daily extended release is effective and well tolerated for the treatment of overactive bladder syndrome: an integrated analysis of two randomised, phase III trials. [2009.12]

Extended-Release Trospium Chloride Improves Quality of Life in Overactive Bladder. [2009.10.08]

Trospium and cognition in patients with late onset Alzheimer disease. [2009.10]

Trospium chloride extended release is effective and well tolerated in women with overactive bladder syndrome. [2009.08.29]

Baseline incontinence severity is predictive of the percentage of patients continent after receiving once-daily trospium chloride extended release. [2009.06]

Trospium Chloride Treatment of Overactive Bladder (February) (CE). [2009.02.03]

Trospium chloride treatment of overactive bladder. [2009.02]

Role of trospium chloride in brachytherapy-related detrusor overactivity. [2008.03]

Comparison of the efficacy and tolerability of solifenacin succinate with or without previous use of trospium chloride. [2007.09]

Trospium chloride: Distinct among other anticholinergic agents available for the treatment of overactive bladder. [2006.11]

Trospium chloride: the European experience. [2006.07]

Randomised, double-blind study of the effects of oxybutynin, tolterodine, trospium chloride and placebo on sleep in healthy young volunteers. [2003]

Other possibly related research studies

The effects of antimuscarinic treatments in overactive bladder: an update of a systematic review and meta-analysis. [2008.09]

Urgency in overactive bladder: Translating experimental data into clinical practice. [2008.05]

Persistence, adherence, and switch rates among extended-release and immediate-release overactive bladder medications in a regional managed care plan. [2008.04]

[Anticholinergic drugs in overactive bladder] [2008.01]

Pharmacologic management of overactive bladder. [2007]

Muscarinic receptor antagonists for overactive bladder. [2007.11]

Overactive bladder treatments in early phase clinical trials. [2007.07]

Treatment of overactive bladder: selective use of anticholinergic agents with low drug-drug interaction potential. [2007.05]

Maximizing anticholinergic therapy for overactive bladder: has the ceiling been reached? [2007.06]

[How do medications used to treat urinary incontinence affect the cerebral function of the elderly?] [2007.04]

Newer agents for the management of overactive bladder. [2006.12.15]

Pharmacoeconomic evaluation of antimuscarinic agents for the treatment of overactive bladder. [2006.12]

Anticholinergic drugs versus placebo for overactive bladder syndrome in adults. [2006.10.18]

Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites? [2006.11]

[Intravesical treatment of overactive bladder syndrome] [2006.10]

Neurogenic bladder treatment by doubling the recommended antimuscarinic dosage. [2006]

[Oral anticholinergics in overactive bladder] [2006.07]

Practical considerations of new drugs: new choices for old problems. [2006.04]

Efficacy, tolerability and safety of propiverine hydrochloride in children and adolescents with congenital or traumatic neurogenic detrusor overactivity--a retrospective study. [2006.06]

Management of overactive bladder and urge urinary incontinence in the elderly patient. [2006.03]

Using anticholinergics to treat overactive bladder: the issue of treatment tolerability. [2006.03]

Muscarinic receptors in the bladder: from basic research to therapeutics. [2006.02]

Preserving cognitive function for patients with overactive bladder: evidence for a differential effect with darifenacin. [2008.08.11]

The effects of reformulation: improved therapeutic index. [2008.11]

Preserving cognitive function for patients with overactive bladder: evidence for a differential effect with darifenacin. [2008.11]

Persistence of antimuscarinic drug use. [2009.03]

Muscarinic receptor antagonists for overactive bladder treatment: does one fit all? [2009.01]

Overactive Bladder Drugs and Constipation: A Meta-Analysis of Randomized, Placebo-Controlled Trials. [2010.07.02]

Update on the treatment of overactive bladder. [2011.07]

New strategies for medical management of overactive bladder in children. [2010.07]

A comprehensive non-clinical evaluation of the CNS penetration potential of antimuscarinic agents for the treatment of overactive bladder. [2011.08]

Adverse event assessment of antimuscarinics for treating overactive bladder: a network meta-analytic approach. [2011.02.23]

Gateways to clinical trials. [2010.07]

Overactive bladder drugs and constipation: a meta-analysis of randomized, placebo-controlled trials. [2011.01]

Benefits and harms of pharmacologic treatment for urinary incontinence in women: a systematic review. [2012]

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