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Salagen (Pilocarpine Hydrochloride) - Published Studies

 
 



Salagen Related Published Studies

Well-designed clinical trials related to Salagen (Pilocarpine)

A 12-week, double-masked, parallel-group study of the safety and efficacy of travoprost 0.004% compared with pilocarpine 1% in Chinese patients with primary angle-closure and primary angle-closure glaucoma. [2011.08]

A phase III randomized, double-blind, placebo-controlled study of pilocarpine for vaginal dryness: North Central Cancer Treatment group study N04CA. [2011.05]

Tramadol-induced oral dryness and pilocarpine treatment: effects on total protein and IgA. [2011.04]

A phase III randomized, double-blind, placebo-controlled study of pilocarpine for vaginal dryness: North Central Cancer Treatment group study N04CA. [2011]

Comparison of the effects of pilocarpine and cevimeline on salivary flow. [2009.05]

Reducing the incidence of 131I-induced sialadenitis: the role of pilocarpine. [2008.04]

Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study. [2008.01.01]

Protection of Salivary Function by Concomitant Pilocarpine During Radiotherapy: A Double-Blind, Randomized, Placebo-Controlled Study. [2007.09.13]

Pilocarpine hydrochloride for the treatment of xerostomia in patients with Sjogren's syndrome in Taiwan--a double-blind, placebo-controlled trial. [2006.10]

The effect of timolol-dorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucoma. [2006.06]

Effect of pilocarpine during radiation therapy: results of RTOG 97-09, a phase III randomized study in head and neck cancer patients. [2006.05]

A randomized study to assess the effectiveness of orally administered pilocarpine during and after radiotherapy of head and neck cancer. [2006.03]

Additivity of pilocarpine to bimatoprost in ocular hypertension and early glaucoma. [2005.06]

Randomized controlled trial of pilocarpine hydrochloride for the moderation of oral mucositis during autologous blood stem cell transplantation. [2005.04]

Laserinterferometric assessment of pilocarpine-induced movement of an accommodating intraocular lens: a randomized trial. [2004.08]

Double-blind randomized, placebo-controlled study of pilocarpine to salvage salivary gland function during radiotherapy of patients with head and neck cancer. [2004.07]

[Usefulness of pilocarpine in the prevention of xerostomia in patients with head and neck cancer treated with radiotherapy. Assessment with gammagraphy and salivary flow] [2004.07]

Oral pilocarpine for treatment of opioid-induced oral dryness in healthy adults. [2004.05]

The efficacy of pilocarpine and bethanechol upon saliva production in cancer patients with hyposalivation following radiation therapy. [2004.02]

[Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients] [2004]

A study of replacement of timolol-pilocarpine with latanoprost in pseudoexfoliation glaucoma. [2003.12]

Oral pilocarpine for the treatment of ocular symptoms in patients with Sjogren's syndrome: a randomised 12 week controlled study. [2003.12]

Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients. [2003.08]

Comparison of the intraocular pressure lowering effect of latanoprost and carteolol-pilocarpine combination in newly diagnosed glaucoma. [2003.01]

A prospective, long-term, randomized study of the efficacy and safety of the drug combination pilocarpine 1% with clonidine 0.06% or clonidine 0.125% versus timolol 0.25%. [2002.12]

A Phase III placebo-controlled trial of oral pilocarpine in patients undergoing radiotherapy for head-and-neck cancer. [2002.09.01]

An investigation into the use of pilocarpine as a sialagogue in patients with radiation induced xerostomia. [2002.09]

A randomized, double-blind, placebo-controlled trial of concomitant pilocarpine with head and neck irradiation for prevention of radiation-induced xerostomia. [2002.07]

Pupillary response to four concentrations of pilocarpine in normal subjects: application to testing for Adie tonic pupil. [2002.03]

Effect of pilocarpine mouthwash on salivary flow. [2002.01]

The influence of pilocarpine and biperiden on pH value and calcium, phosphate, and bicarbonate concentrations in saliva during and after radiotherapy for head and neck cancer. [2001.11]

Double-blind, placebo-controlled cross-over study of oral pilocarpine for the prevention of chemotherapy-induced oral mucositis in adult patients with cancer. [2001.11]

Salivary scintigraphy for assessing the protective effect of pilocarpine in head and neck irradiated tumours. [2001.06]

Potential mechanism for the additivity of pilocarpine and latanoprost. [2001.06]

Randomized double blind, placebo-controlled study of pilocarpine administered during head and neck irradiation to reduce xerostomia. [2001.02]

The acute effect of pilocarpine on pulsatile ocular blood flow in ocular hypertension. [2001.02]

Twenty-four hour intraocular pressure reduction with latanoprost compared with pilocarpine as third-line therapy in exfoliation glaucoma. [2001.02]

Intracameral pilocarpine in topical phacoemulsification. [2000.12]

Post-radiation severe xerostomia relieved by pilocarpine: a prospective French cooperative study. [2000.06]

The additive intraocular pressure-lowering effect of latanoprost 0.005% daily once and pilocarpine 2% t.i.d. in patients with open-angle glaucoma or ocular hypertension. a 6-month, randomized, multicenter study. German Latanoprost Study Group. [2000.05]

Comparison of the intraocular pressure lowering effect of latanoprost and a fixed combination of timolol-pilocarpine eye drops in patients insufficiently controlled with beta adrenergic antagonists. French Latanoprost Study Group, and the Swedish Latanoprost Study Group. [2000.02]

Pilocarpine in the prevention of postirradiation xerostomia. [2000]

The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group. [1999.10]

The effect of pilocarpine and biperiden on salivary secretion during and after radiotherapy in head and neck cancer patients. [1999.09.01]

Comparison of dorzolamide and pilocarpine as adjunctive therapy in patients with open-angle glaucoma and ocular hypertension. [1999.09]

Efficacy of apraclonidine 1% versus pilocarpine 4% for prophylaxis of intraocular pressure spike after argon laser trabeculoplasty. [1999.06]

Intraocular pressure-lowering effects of latanoprost monotherapy versus latanoprost or pilocarpine in combination with timolol: a randomized, observer-masked multicenter study in patients with open-angle glaucoma. Italian Latanoprost Study Group. [1999.02]

Effects of dipivefrin and pilocarpine on pupil diameter, automated perimetry and LogMAR acuity. [1999.02]

Pilocarpine tablets for the treatment of dry mouth and dry eye symptoms in patients with Sjogren syndrome: a randomized, placebo-controlled, fixed-dose, multicenter trial. P92-01 Study Group. [1999.01.25]

A comparison of the effects of betaxolol, timolol, and pilocarpine on visual function in patients with open-angle glaucoma. [1998.08]

A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life. [1998.07]

A comparison of artificial saliva and pilocarpine in the management of xerostomia in patients with advanced cancer. [1998.03]

Comparison of two fixed beta-blocker-pilocarpine combinations. The Carteolol-Pilocarpine Study Group. [1997.10]

A comparative study of Ocusert Pilo 40, intensive pilocarpine and low-dose pilocarpine in the initial treatment of primary acute angle-closure glaucoma. [1997]

Dorzolamide versus pilocarpine as adjunctive therapies to timolol: a comparison of patient preference and impact on daily life. [1996.09]

A new transdermal delivery system for pilocarpine in glaucoma treatment. [1996.09]

The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group. [1996.08]

Determination of the efficacy of topical oral pilocarpine for postirradiation xerostomia in patients with head and neck carcinoma. [1996.08]

A comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%. [1996.06]

Fixed combination of carteolol and pilocarpine eye-drops: a double-blind randomized cross-over trial versus carteolol alone on intra-ocular pressure. The Study Group. [1996.01]

Ocular hypotensive efficacy and safety of a combined formulation of betaxolol and pilocarpine. [1996]

Reversal of tropicamide mydriasis with single instillations of pilocarpine can induce substantial pseudo-myopia in young adults. [1995.09]

Pharmacodynamic effects of pilocarpine eye drop enhanced by decreasing its volume of instillation. [1995.07]

The additive miotic effects of dapiprazole and pilocarpine. [1995.07]

Primary argon laser trabeculoplasty vs pilocarpine. IV. Long-term effects on optic nerve head. [1995.06]

Oral pilocarpine for radiation-induced xerostomia: integrated efficacy and safety results from two prospective randomized clinical trials. [1995.02.01]

Phenylephrine and pilocarpine in the treatment of post-operative irido-corneal adhesion. [1995]

[Efficacy and tolerability of 2 presentations of eyedrops combining carteolol 2% and pilocarpine 2% in primary open-angle glaucoma and simple ocular hypertension] [1995]

Effect of topically applied 2% pilocarpine and 0.25% demecarium bromide on blood-aqueous barrier permeability in dogs. [1994.12]

A comparison of artificial saliva and pilocarpine in radiation-induced xerostomia. [1994.08]

Efficacy and safety of timolol/pilocarpine combination drops in glaucoma patients. [1994.08]

A comparison of the efficacy of various metipranolol-pilocarpine combinations in patients with ocular hypertension and primary open-angle glaucoma. [1994.06]

Primary argon laser trabeculoplasty vs pilocarpine. II: Long-term effects on intraocular pressure and facility of outflow. Study design and additional therapy. [1994.04]

Influence of apraclonidine and pilocarpine alone and in combination on post laser trabeculoplasty pressure rise. [1994.01]

Oral pilocarpine for post-irradiation xerostomia in patients with head and neck cancer. [1993.08.05]

A multicenter, randomized, double-blind, placebo-controlled, dose-titration study of oral pilocarpine for treatment of radiation-induced xerostomia in head and neck cancer patients. [1993.06]

Interaction of PhXA41, a new prostaglandin analogue, with pilocarpine. A study on patients with elevated intraocular pressure. [1993.05]

Pilocarpine drops do not reduce intraocular pressure sufficiently in pseudoexfoliation glaucoma. [1993]

Timolol-pilocarpine fixed-ratio combinations in the treatment of chronic open angle glaucoma. A controlled multicenter study of 48 weeks. Scandinavian Timpilo Study Group. [1992.12]

Effect of timolol versus pilocarpine on visual field progression in patients with primary open-angle glaucoma. [1992.10]

Primary argon laser trabeculoplasty vs. pilocarpine. Short-term effects. [1992.08]

Therapeutic index of pilocarpine, carbachol, and timolol with nasolacrimal occlusion. [1992.07.15]

Effects of pilocarpine and tropicamide on blood-aqueous barrier permeability in man. [1992.02]

Effects of pilocarpine on salivary flow in patients with Sjogren's syndrome. [1991.11]

Pilocarpine treatment of salivary gland hypofunction and dry mouth (xerostomia). [1991.06]

Occurrence of disc haemorrhages in open-angle glaucoma treated with pilocarpine or timolol. [1991.04]

Pilocarpine to prevent acute pressure increase following primary laser trabeculoplasty. [1991]

The combined use of apraclonidine and pilocarpine during laser iridotomy in a Hispanic population. [1990.12]

Twelve-hour IOP control obtained by a single dose of timolol/pilocarpine combination eye drops. [1990.06]

[Decrease in intraocular pressure following administration of the local carbonic anhydrase inhibitor (MK-927)--comparison of the effect with pilocarpine] [1990]

Treatment of radiation side effects with oral pilocarpine. [1989.12]

Timolol-pilocarpine combined vs timolol and pilocarpine given separately. [1989.05.15]

Relative bioavailability of pilocarpine from a novel ophthalmic delivery system and conventional eyedrop formulations. [1989.05]

Reduced cyclic myopia with pilocarpine gel. [1988.04]

A comparative evaluation of timolol maleate and pilocarpine in the treatment of chronic open angle glaucoma. [1988]

A double-masked study of timolol and pilocarpine combined. [1987.12.15]

[Effectiveness and tolerance of an active combination of timolol and pilocarpine--a pilot project] [1987.12]

[Changes in lung function following administration of eyedrops containing timolol, metipranolol, pindolol and pilocarpine in healthy probands and patients with mild bronchial asthma] [1987.10.01]

Timolol/pilocarpine combination eye drops in open angle glaucoma and in ocular hypertension. A controlled randomized study. [1987.10]

Well-designed clinical trials possibly related to Salagen (Pilocarpine)

A randomized intraindividual comparison of the accommodative performance of the bag-in-the-lens intraocular lens in presbyopic eyes. [2010.11]

Treatment of primary Sjogren syndrome: a systematic review. [2010.07.28]

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