Salagen (Pilocarpine Hydrochloride) - Summary

SALAGEN SUMMARY

SALAGEN® Tablets contain pilocarpine hydrochloride, a cholinergic agonist for oral use. Pilocarpine hydrochloride is a hygroscopic, odorless, bitter tasting white crystal or powder which is soluble in water and alcohol and virtually insoluble in most non-polar solvents.

SALAGEN® Tablets are indicated for 1) the treatment of symptoms of dry mouth from salivary gland hypofunction caused by radiotherapy for cancer of the head and neck; and 2) the treatment of symptoms of dry mouth in patients with Sjogren's Syndrome.

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SALAGEN NEWS HIGHLIGHTS

Published Studies Related to Salagen (Pilocarpine)

Reducing the incidence of 131I-induced sialadenitis: the role of pilocarpine. [2008.04]

Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study. [2008.01.01]

Protection of Salivary Function by Concomitant Pilocarpine During Radiotherapy: A Double-Blind, Randomized, Placebo-Controlled Study. [2007.09.13]

Pilocarpine hydrochloride for the treatment of xerostomia in patients with Sjogren's syndrome in Taiwan--a double-blind, placebo-controlled trial. [2006.10]

The effect of timolol-dorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucoma. [2006.06]

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Clinical Trials Related to Salagen (Pilocarpine)

A Comparison of Orally Pilocarpine and Artificial Saliva in Xerostomy Treatment [Completed]

Trial Comparing Oral Pilocarpine (Salagen) Versus Submandibular Salivary Gland Transfer Protocol, For the Prevention of Radiation (XRT) Induced Xerostomia in Head and Neck Cancer Patients [Recruiting]

Pilocarpine in Treating Patients With Dry Mouth Caused by Opioids [Active, not recruiting]

Bioequivalency Study of 5 mg Pilocarpine Tablets Under Fasting Conditions [Completed]

Bioequivalency Study of 7.5 mg Pilocarpine Under Fed Conditions [Completed]

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