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Roxicodone (Oxycodone Hydrochloride) - Summary

 
 



ROXICODONE SUMMARY

ROXICODONE®
(Oxycodone Hydrochloride
Tablets USP)

ROXICODONE« (oxycodone hydrochloride tablets USP) is an opioid analgesic. Each tablet for oral administration contains 15 mg or 30 mg of oxycodone hydrochloride USP.

ROXICODONE« tablets are an immediate-release oral formulation of oxycodone hydrochloride indicated for the management of moderate to severe pain where the use of an opioid analgesic is appropriate.


See all Roxicodone indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Roxicodone (Oxycodone)

Osteopathic manipulative therapy significantly improves low back pain in postpartum women
Source: Bones / Orthopedics News From Medical News Today [2015.07.01]
German researchers found osteopathic manipulative therapy (OMTh) decreased postpartum low back pain by over 70 percent in women who had given birth at least three months before beginning treatment...

Aching Foot Makes OA-Related Knee Pain Worse (CME/CE)
Source: MedPage Today Neurology [2015.07.01]
(MedPage Today) -- Clinicians should consider evaluating the foot and ankle of osteoarthritis patients

Gender difference in pain transmission, reports new study
Source: Immune System / Vaccines News From Medical News Today [2015.06.30]
A mouse study has found that different immune cells in males and females are responsible for the transmission of pain, raising questions about human pain drug development.

TIVORBEX now available in U.S. pharmacies for the treatment of acute pain
Source: Pain / Anesthetics News From Medical News Today [2015.06.29]
Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, has announced that TIVORBEX® (indomethacin) capsules, a nonsteroidal...

Many Doctors Underestimate Risks of Prescription Painkillers: Survey
Source: MedicineNet Chronic Pain Specialty [2015.06.29]
Title: Many Doctors Underestimate Risks of Prescription Painkillers: Survey
Category: Health News
Created: 6/26/2015 12:00:00 AM
Last Editorial Review: 6/29/2015 12:00:00 AM

more news >>

Published Studies Related to Roxicodone (Oxycodone)

Comparison of subjective effects of extended-release versus immediate-release oxycodone/acetaminophen tablets in healthy nondependent recreational users of prescription opioids: a randomized trial. [2014]
[APAP]) formulation with those of immediate-release (IR) OC/APAP... CONCLUSIONS: Extended-release OC/APAP produced lower subjective drug effects than

A randomized, double-blind, placebo-controlled study of oral oxycodone plus acetaminophen for the treatment of pain in photodynamic therapy on port wine stains. [2014]
efficacy and safety of an oral analgesic for the treatment of pain in PDT on PWS... CONCLUSIONS: The time of the pain beginning was 8.31 ┬▒ 4.58 min in

Bowel function after tapentadol and oxycodone immediate release (IR) treatment in patients with low back or osteoarthritis pain. [2013]
OBJECTIVES: Constipation is a common side effect of opioid therapy. Tapentadol immediate release (IR) was better tolerated than oxycodone IR in 2 clinical trials involving patients with low back or osteoarthritis pain... DISCUSSION: Patient-reported bowel function associated with tapentadol IR treatment was similar to that associated with placebo (10-d trial) and significantly better than that associated with oxycodone IR treatment (10- and 90-d trials).

Diclofenac with or without an antiemetic for acute migraine headaches in adults. [2013]
CONCLUSIONS: Oral diclofenac potassium 50 mg is an effective treatment

Comparison of the efficacy and safety of dual-opioid treatment with morphine plus oxycodone versus oxycodone/acetaminophen for moderate to severe acute pain after total knee arthroplasty. [2013]
oxycodone/acetaminophen and fixed low-dose morphine/oxycodone... CONCLUSIONS: Flexible dose morphine/oxycodone was superior to low-dose

more studies >>

Clinical Trials Related to Roxicodone (Oxycodone)

Oxycodone-Naloxone Prolonged Release Tablets in Relieving Opioid-Related Constipation [Active, not recruiting]

Oxycodone-Naloxone in Relieving Opioid-Related Constipation [Active, not recruiting]
The primary objective of this study is to demonstrate that subjects with moderate to severe non-malignant pain taking oxycodone/naloxone prolonged release tablets have improvement in symptoms of constipation compared to subjects taking oxycodone prolonged release tablets alone.

Oxycodone for Labor Pain - Pharmacokinetics (PK), Safety and Efficacy [Not yet recruiting]
Childbirth is one of the most painful events that a woman is likely to experience, and thus is a major concern for most parturient. Severe pain releases stress mediators and may thus compromise fetus well-being if placental perfusion is decreased. Epidural analgesia is the golden standard for the management of severe labor pain. However, it could not always be used both due the parturient related factors and the organizational reasons. However, the knowledge on safety and efficacy of oxycodone involving mother, fetus and newborn is limited.

Aim of the study is firstly, to evaluate the efficacy and safety of oxycodone in labor pain healthy parturients. Secondly, to measure parturient's blood oxycodone concentration during labour and fetal concentration from placental umbilical vein and artery right after birth.

Open-Label Trial Comparing Oxycodone Medications [Recruiting]
The investigators hypothesize that subjects will have greater pain relief when taking IR-oxycodone compared with ER-oxycodone for several reasons. The ability to take a varying amount of medication at six different points over the course of a day will allow patients to take as much (or as little) medication as they need to control their pain. In addition, the ability to vary the medication doses in this way will give them a greater sense of control, which will also contribute to greater pain relief. Similarly, the investigators predict that patients will show greater benefits with IR-oxycodone on the measures of physical and emotional functioning. Because there is relatively little data on sleep apnea in chronic pain patients (Webster et al., 2008), these assessments are exploratory and not hypothesis-based. Finally, although it is typically thought that the abuse liability of IR-opioid medications is greater than for ER-medications, the data on which this belief are based have not involved systematic studies of patients with chronic pain; the assessments of abuse liability will therefore also be exploratory.

Morphine vs. Oxycodone for Postoperative Pain Management [Recruiting]
The purpose of this study is to determine whether oxycodone provides better analgesia compared to morphine after laparoscopic hysterectomy or myomectomy.

more trials >>

Reports of Suspected Roxicodone (Oxycodone) Side Effects

Respiratory Arrest (25)Completed Suicide (23)Cardiac Arrest (18)Pain (17)Drug Dependence (14)Substance Abuse (12)Drug Withdrawal Syndrome (12)Dizziness (11)Confusional State (9)Multiple Drug Overdose (9)more >>


Page last updated: 2015-07-01

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