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Robinul (Glycopyrrolate) - Summary

 


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ROBINUL SUMMARY

Robinul Injection (glycopyrrolate injection, USP)

ROBINUL (glycopyrrolate) Injection is a synthetic anticholinergic agent.

Robinul (Glycopyrrolate) is indicated for the following:

In Anesthesia

ROBINUL Injection is indicated for use as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions; to reduce the volume and free acidity of gastric secretions; and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. When indicated, ROBINUL Injection may be used intraoperatively to counteract surgically or drug-induced or vagal reflexes associated arrhythmias. Glycopyrrolate protects against the peripheral muscarinic effects (e.g., bradycardia and excessive secretions) of cholinergic agents such as neostigmine and pyridostigmine given to reverse the neuromuscular blockade due to non-depolarizing muscle relaxants.

In Peptic Ulcer

For use in adults as adjunctive therapy for the treatment of peptic ulcer when rapid anticholinergic effect is desired or when oral medication is not tolerated.


See all Robinul indications & dosage >>

ROBINUL NEWS HIGHLIGHTS

Published Studies Related to Robinul (Glycopyrrolate)

Intramuscular neostigmine and glycopyrrolate safely accelerated bowel evacuation in patients with spinal cord injury and defecatory disorders. [2008.10]

Sugammadex reversal of rocuronium-induced neuromuscular blockade: a comparison with neostigmine-glycopyrrolate and edrophonium-atropine. [2007.03]

Glycopyrrolate does not reduce the incidence of perioperative adverse events in children with upper respiratory tract infections. [2007.02]

Glycopyrrolate during sevoflurane-remifentanil-based anaesthesia for cardiac catheterization of children with congenital heart disease. [2005.11]

Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma. [2005.10]

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Clinical Trials Related to Robinul (Glycopyrrolate)

Efficacy and Safety Study of Oral Glycopyrrolate Liquid to Manage Problem Drooling Associated With Cerebral Palsy or Other Neurologic Conditions in Children [Completed]

Safety Study of Oral Glycopyrrolate Liquid for the Treatment of Pathologic (Chronic Moderate to Severe) Drooling in Pediatric Patients 3 to 18 Years of Age With Cerebral Palsy or Other Neurologic Condition [Active, not recruiting]

Efficacy and Safety of Four Doses of Glycopyrronium Bromide in Patients With Stable Chronic Obstructive Pulmonary Disease (COPD), in Comparison to an Active Comparator Tiotropium [Completed]

Echocardiographic Study of the Haemodynamic Effects of Remifentanil With and Without Glycopyrrolate in Healthy Children [Recruiting]

Safety and Tolerability of 28 Days Treatment With Glycopyrrolate(NVA237) (100 or 200µg Once a Day) in Patients With Moderate to Severe COPD [Completed]

more >>

Page last updated: 2008-11-03

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