Robaxin (Methocarbamol) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The following adverse reactions have been reported coincident with the administration of methocarbamol. Some events may have been due to an overly rapid rate of intravenous injection.

Body as a Whole

Anaphylactic reaction, angioneurotic edema, fever, headache

Cardiovascular System

Bradycardia, flushing, hypotension, syncope, thrombophlebitis

In most cases of syncope there was spontaneous recovery. In others, epinephrine, injectable steroids, and/or injectable antihistamines were employed to hasten recovery.

Digestive System

Dyspepsia, jaundice (including cholestatic jaundice), nausea and vomiting

Hemic and Lymphatic System

Leukopenia

Immune System

Hypersensitivity reactions

Nervous System

Amnesia, confusion, diplopia, dizziness or light-headedness, drowsiness, insomnia, mild muscular incoordination, nystagmus, sedation, seizures (including grand mal), vertigo

The onset of convulsive seizures during intravenous administration of methocarbamol has been reported in patients with seizure disorders. The psychic trauma of the procedure may have been a contributing factor. Although several observers have reported success in terminating epileptiform seizures with ROBAXIN Injectable, its administration to patients with epilepsy is not recommended (see PRECAUTIONS, General).

Skin and Special Senses

Blurred vision, conjunctivitis, nasal congestion, metallic taste, pruritus, rash, urticaria

Other

Pain and sloughing at the site of injection

REPORTS OF SIDE EFFECTS / ADVERSE REACTIONS RELATED TO ROBAXIN

Possible Robaxin side effects / adverse reactions in 39 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2007-04-04

Patient: 39 year old female weighing 80.7 kg (177.5 pounds)

Reactions: Confusional State, Contusion, Subcutaneous Abscess, Pleural Adhesion, Fall, Drug Toxicity, Panniculitis, Cerebral Infarction, Dehydration, Hepatic Congestion, Thyroiditis Chronic, Myocardial Fibrosis, Gastroenteritis Viral

Adverse event resulted in: death

Suspect drug(s):
Ativan
    Indication: Drug USE FOR Unknown Indication

Benadryl
    Indication: Drug USE FOR Unknown Indication

Klonopin
    Indication: Drug USE FOR Unknown Indication

Noctec
    Administration route: Oral
    Indication: Insomnia

Robaxin
    Indication: Drug USE FOR Unknown Indication

Soma
    Indication: Drug USE FOR Unknown Indication

Tamiflu
    Administration route: Oral
    Start date: 2007-02-05

Valium
    Indication: Drug USE FOR Unknown Indication

Other drugs received by patient: Methadone HCL; Nutropin; Vitamin B-12; Immunoglobulin Injectable; Cipro; Topamax; Acetaminophen

Possible Robaxin side effects / adverse reactions in 49 year old female

Reported by a physician from United States on 2007-06-11

Patient: 49 year old female weighing 94.3 kg (207.5 pounds)

Reactions: Multiple Drug Overdose Intentional

Adverse event resulted in: death

Suspect drug(s):
Oxycontin
    Dosage: 40 mg, bid, oral
    Administration route: Oral
    Indication: Back Pain
    Start date: 2005-01-01

Robaxin
    Dosage: 750 mg, tid, oral
    Administration route: Oral
    Indication: Muscle Spasms

Trazodone HCL
    Dosage: 200 mg, hs, oral
    Administration route: Oral
    Indication: Depression

Other drugs received by patient: Oxyir; Neurontin

Possible Robaxin side effects / adverse reactions in 64 year old male

Reported by a physician from United States on 2007-06-20

Patient: 64 year old male

Reactions: Pharmaceutical Product Complaint, Constipation

Suspect drug(s):
Robaxin