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Robaxin (Methocarbamol) - Summary

 

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ROBAXIN SUMMARY

ROBAXIN Injectable (methocarbamol injection, USP)
Rx only

ROBAXIN (methocarbamol injection, USP) Injectable, a carbamate derivative of guaifenesin, is a central nervous system (CNS) depressant with sedative and musculoskeletal relaxant properties. It is a sterile, pyrogen-free solution intended for intramuscular or intravenous administration. Each mL contains: methocarbamol, USP 100 mg, polyethylene glycol 300, NF 0.5 mL, Water for Injection, USP q. s. The pH is adjusted, when necessary, with hydrochloric acid and/or sodium hydroxide.

The injectable form of methocarbamol is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Methocarbamol does not directly relax tense skeletal muscles in man.

ROBAXIN NEWS HIGHLIGHTS

Published Studies Related to Robaxin (Methocarbamol)

Subjective and behavioral effects of diphenhydramine, lorazepam and methocarbamol: evaluation of abuse liability. [1992.08]

Antagonist effects of nalbuphine in opioid-dependent human volunteers. [1989.03]

Does methocarbamol affect fatigue markers in the low-back electromyogram? [1998.12]

Pain reduction in breast augmentation using methocarbamol. [1997.01]

The pharmacology and pharmacokinetics of high-dose methocarbamol in horses. [1992.02]

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Clinical Trials Related to Robaxin (Methocarbamol)

A Pilot Study of Recombinant Human Relaxin (rhRlx) in Compensated Congestive Heart Failure [Completed]

Recombinant Human Relaxin for the Treatment of Decompensated CHF [Active, not recruiting]

Efficacy and Safety of Relaxin for the Treatment of Acute Heart Failure [Recruiting]

Evaluation of the Safety of Relaxin in Preeclampsia [Recruiting]

Recombinant Human Relaxin (rhRlx) in Pregnant Women Scheduled for Induction of Labor [Completed]

more>>

Page last updated: 2007-06-01

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