NEWS HIGHLIGHTSMedia Articles Related to Rhinocort (Budesonide)
Nonallergic Rhinitis Symptoms More Severe Than Allergic Rhinitis
Source: Allergy News From Medical News Today [2009.10.06]
A comparison of symptoms in patients with allergic rhinitis (AR) and non-allergic rhinitis (NAR) revealed that those with the NAR experienced worse symptoms. The findings are according to new research presented at the 2009 American Academy of Otolaryngology-Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO, in San Diego, CA.
Patients With Allergic Rhinitis And Obstructive Sleep Apnea Plagued By Stress, Fatigue
Source: Allergy News From Medical News Today [2009.10.06]
Patients who suffer from both allergic rhinitis and obstructive sleep apnea (OSA) may experience escalated symptoms of stress and fatigue. In a paper presented at the 2009 American Academy of Otolaryngology - Head and Neck Surgery Foundation (AAO-HNSF) Annual Meeting & OTO EXPO in San Diego, researchers studied 34 people who were diagnosed with obstructive sleep apnea. Among them, 12 people were classified in the allergic rhinitis group and 22 people in the control group.
Botox Sponge Treats Intrinsic Rhinitis Without Needles
Source: Ear, Nose and Throat News From Medical News Today [2009.10.16]
Injecting botulinum toxin (botox) to treat intrinsic or allergic rhinitis may be a thing of the past as researchers have now shown that sponges soaked in botox are equally effective in treating the condition. The research published in BioMed Central's open access journal Head & Face Medicine offers a potential needle-free treatment to the millions of people who suffer from rhinitis.
STALLERGENES: Immunotherapy Tablet Containing Recombinant Allergen (rBet V 1) Of Birch Pollen: Positive Results For A Phase IIb/III Trial
Source: Allergy News From Medical News Today [2009.09.17]
Stallergenes S.A. has announced the first results of a new phase IIb/III clinical trial (VO59.08) conducted in allergic rhinitis caused by birch pollen and concerning the development of a sublingual immunotherapy tablet containing the recombinant allergen of this pollen, rBet v 1. This study is the first ever to use a recombinant allergen as an active substance. To Stallergenes' knowledge, the use of a recombinant protein in dry form is also a world first. The VO59.
Chlorinated Pools Increase Risk Of Allergic Diseases
Source: Allergy News From Medical News Today [2009.09.15]
Chlorine is effective at killing pathogens in swimming pools, but it also irritates the skin, eyes and upper respiratory tract of swimmers. Recent research has found swimming in outdoor or indoor chlorinated pools can increase asthma risks. The study, "Impact of Chlorinated Swimming Pool Attendance on the Respiratory Health of Adolescents" found that children who swam in chlorinated pools had a higher risk of asthma, as well as other allergic diseases such as hay fever and allergic rhinitis.
Published Studies Related to Rhinocort (Budesonide)
An economic evaluation of budesonide/formoterol for maintenance and reliever treatment in asthma in general practice. [2009.09.19]
INTRODUCTION: In budesonide/formoterol (Symbicort(R) Turbuhaler(R), AstraZeneca, Lund, Sweden) maintenance and reliever therapy (SMART), patients with asthma take a daily maintenance dose of budesonide/formoterol, with the option of taking additional doses for symptom relief instead of a short-acting beta(2)-agonist (SABA). This study assesses the cost-effectiveness of SMART compared with usual care in patients with mild-to-moderate persistent asthma treated by general practitioners in the Netherlands from a societal perspective... CONCLUSIONS: Treating primary care patients with mild-to-moderate persistent asthma with SMART instead of ICS plus bronchodilators does not affect health outcomes and does not increase costs; therefore, is likely to be an alternative for guideline-directed treatment, from a health and economic perspective.
Aerosolized L epinephrine vs Budesonide for Postextubation Stridor A Randomized Controlled Trial. [2009.09.03]
Objective: To compare the efficacy and adverse effects of aerosolized Lepinephrine vs budesonide in the treatment of postextubation stridor... However, epinephrine showed a more sustained effect.
A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma. [2009.09.01]
CONCLUSIONS: Ipilimumab shows activity in advanced melanoma, with encouraging survival and manageable adverse events. Budesonide should not be used prophylactically for grade >or=2 diarrhea associated with ipilimumab therapy.
Grapefruit juice interaction with oral budesonide: equal effect on immediate-release and delayed-release formulations. [2009.07]
Grapefruit juice (GFJ) inhibits CYP3A activity in the gut wall, thereby decreasing first-pass metabolism of CYP3A substrates...
Efficacy and tolerability of once-daily budesonide/formoterol pressurized metered-dose inhaler in adults and adolescents with asthma previously stable with twice-daily budesonide/ formoterol dosing. [2009.07]
BACKGROUND: The goal of asthma therapy is to control symptoms using minimal pharmacologic intervention. OBJECTIVE: To evaluate the efficacy and tolerability of once-daily budesonide/formoterol vs once-daily budesonide in patients stable with twice-daily budesonide/formoterol... CONCLUSIONS: Pulmonary function and asthma control were more effectively maintained with all budesonide/formoterol regimens vs once-daily budesonide and with twice-daily budesonide/formoterol at twice the daily formoterol dose vs both once-daily budesonide/formoterol doses.
Clinical Trials Related to Rhinocort (Budesonide)
Assess the Efficacy and Safety of Rhinocort Aqua [Completed]
The purpose of this study is to compare Rhinocort with placebo in pediatric subjects aged 2-5
years with allergic rhinitis to study effects on nasal symptoms such as sneezing, runny and
stuffy noses.
Rhinocort Aqua Versus Placebo and Fluticasone Propionate [Completed]
The purpose of this study is to compare once daily treatment with Rhinocort against placebo
and Fluticasone Propionate at reliving the nasal symptoms of seasonal allergic rhinitis.
Adults With Moderate to Severe Asthma [Completed]
A study to compare the safety and effectiveness of 5 different ways of taking Pulmicort when
given to asthma patients aged 12 years and above.
New Nasal Applicator / New Formulation - User Study [Completed]
The purpose of this study is to compare the efficacy of once daily dosing with Rhinocort
Aqua (new formulation) against Rhinocort Aqua (current formulation) and placebo in reliving
the symptoms of seasonal allergic rhinitis (SAR).
New Version Pulmicort Turbuhaler USA Children [Completed]
A comparison of the safety, efficacy and budesonide pharmacokinetics of the currently
approved Pulmicort Turbuhaler with a new version of the inhaler, in children and adolescents
who have asthma. In addition the study evaluated the functionality of the new inhaler at the
end of its intended life.
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