Revatio (Sildenafil Citrate) - News

News related to Revatio (Sildenafil) and/or conditions it is approved for

Is Sildenafil Safe In Cirrhosis Patients?
Source: Hypertension News From Medical News Today [2008.11.13]
Sildenafil is valuable in the treatment of erectile dysfunction and pulmonary hypertension in patients with end-stage liver disease through inhibition of the type-5 phosphodiesterase. The type-5 phosphodiesterase is also present in human mesenteric arteries. The effect of sildenafil on splanchnic blood flow and portal hypertension remains essentially unknown.