Revatio (Sildenafil Citrate) - Summary

REVATIO SUMMARY

REVATIO™, an oral therapy for pulmonary arterial hypertension, is the citrate salt of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type-5 (PDE5). Sildenafil is also marketed as VIAGRA^® for male erectile dysfunction.

REVATIO is indicated for the treatment of pulmonary arterial hypertension (WHO Group I) to improve exercise ability.

The efficacy of REVATIO has not been evaluated in patients currently on bosentan therapy.

REVATIO NEWS HIGHLIGHTS

Media Articles Related to Revatio (Sildenafil)

Health Canada Advises Consumers Not To Use Rize 2 The Occasion Capsules Or Any Unauthorized Erectile Dysfunction Products
Source: Erectile Dysfunction / Premature Ejaculation News From Medical News Today [2008.08.07]

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Published Studies Related to Revatio (Sildenafil)

Effect of sildenafil on clitoral blood flow and sexual response in postmenopausal women with orgasmic dysfunction. [2008.08]

Sildenafil treatment of women with antidepressant-associated sexual dysfunction: a randomized controlled trial. [2008.07.23]

Sildenafil citrate efficacy 8 h postdose in men with mild to moderate erectile dysfunction. [2008.07]

Self-esteem, confidence and relationship satisfaction in men with erectile dysfunction: a randomized, parallel-group, double-blind, placebo-controlled study of sildenafil in Mexico. [2008.07]

Effect of Sildenafil Citrate on the Male Sexual Experience Assessed with the Sexual Experience Questionnaire: A Multicenter, Double-Blind, Placebo-Controlled Trial with Open-Label Extension. [2008.06.17]

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Clinical Trials Related to Revatio (Sildenafil)

A Multicenter, Double-Blind Study to Evaluate the Effect of Pretreatment With a Daily Dose of Sildenafil on the As-Needed Efficacy of Viagra in Men With Erectile Dysfunction and Type 2 Diabetes [Completed]

A Placebo-Controlled Single-Dose Trial of Sildenafil in Schizophrenia [Completed]

Sildenafil Citrate in Waldenstrom's Macroglobulinemia [Terminated]

Acute Effects of Sildenafil on Endothelial Function in People With Diabetes [Completed]

A Study to Assess the Efficacy and Safety of 20, 40, and 80mg of Sildenafil Three Times a Day in the Treatment of Pulmonary Arterial Hypertension [Completed]

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