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Retin-A (Tretinoin Topical) - Published Studies

 
 



Retin-A Related Published Studies

Well-designed clinical trials related to Retin-A (Tretinoin Topical)

Tretinoin cyclodextrin complex (RA/CyD) causes less irritation with an equal antiwrinkle effect compared with conventional tretinoin: clinical and histologic studies of photoaged skin. [2012]

A randomized, double-blind, placebo-controlled, pilot study to assess the efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for the treatment of acne rosacea over 12 weeks. [2012]

A randomized, double-blind, controlled comparative trial of the anti-aging properties of non-prescription tri-retinol 1.1% vs. prescription tretinoin 0.025%. [2012]

Retinoic acid reduces chemotherapy-induced neuropathy in an animal model and patients with lung cancer. [2011.09.06]

Further enhancement of facial appearance with a hydroquinone skin care system plus tretinoin in patients previously treated with botulinum toxin Type A. [2011.07]

Cortexolone 17alpha-propionate 1% cream, a new potent antiandrogen for topical treatment of acne vulgaris. A pilot randomized, double-blind comparative study vs. placebo and tretinoin 0.05% cream. [2011.07]

Comparison of micronized tretinoin gel 0.05% and tretinoin gel microsphere 0.1% in young adolescents with acne: a post hoc analysis of efficacy and tolerability data. [2011.06]

Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A. [2011.04]

Comparison of tretinoin 0.05% cream and 3% alcohol-based salicylic acid preparation in the treatment of acne vulgaris. [2011.03]

Comparison between 1% tretinoin peeling versus 70% glycolic acid peeling in the treatment of female patients with melasma. [2011]

Randomized tolerability analysis of clindamycin phosphate 1.2%-tretinoin 0.025% gel used with benzoyl peroxide wash 4% for acne vulgaris. [2010.12]

Irritation potential of tretinoin gel microsphere pump versus adapalene plus benzoyl peroxide gel. [2010.08]

Randomized phase II trial of All-trans-retinoic acid with chemotherapy based on paclitaxel and cisplatin as first-line treatment in patients with advanced non-small-cell lung cancer. [2010.07.20]

Tretinoin gel microsphere pump 0.04% plus 5% benzoyl peroxide wash for treatment of acne vulgaris: morning/morning regimen is as effective and safe as morning/evening regimen. [2010.07]

Cost-effectiveness of oral alitretinoin in patients with severe chronic hand eczema--a long-term analysis from a Swiss perspective. [2010.06.25]

Very long-term outcome of acute promyelocytic leukemia after treatment with all-trans retinoic acid and chemotherapy: the European APL Group experience. [2010.03.04]

A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen. [2010.03]

Treating photodamage of the decolletage area with a novel copper zinc malonate complex plus hydroquinone and tretinoin. [2010.03]

The impact on outcome of the addition of all-trans retinoic acid to intensive chemotherapy in younger patients with nonacute promyelocytic acute myeloid leukemia: overall results and results in genotypic subgroups defined by mutations in NPM1, FLT3, and CEBPA. [2010.02.04]

Successful retreatment with alitretinoin in patients with relapsed chronic hand eczema. [2010.02.01]

A randomized, investigator-blinded trial to assess the antimicrobial efficacy of a benzoyl peroxide 5%/ clindamycin phosphate 1% gel compared with a clindamycin phosphate 1.2%/tretinoin 0.025% gel in the topical treatment of acne vulgaris. [2010.02]

Alitretinoin for severe chronic hand Eczema: a NICE single technology appraisal. [2010]

Successful retreatment with alitretinoin in patients with relapsed chronic hand eczema. [2010]

Tolerability of high-dose topical tretinoin: the Veterans Affairs Topical Tretinoin Chemoprevention Trial. [2009.10]

Benefits of using a hydroquinone/tretinoin skin care system in patients undergoing intense pulsed light therapy for photorejuvenation: a placebo-controlled study. [2009.09]

Quality of life in the actinic neoplasia syndrome: The VA Topical Tretinoin Chemoprevention (VATTC) Trial. [2009.08]

Comparative efficacy and safety results of two topical combination acne regimens. [2009.07]

Reappraising the phototoxicity of tretinoin: a report of four controlled clinical trials. [2009.06]

Clindamycin lotion alone versus combination lotion of clindamycin phosphate plus tretinoin versus combination lotion of clindamycin phosphate plus salicylic acid in the topical treatment of mild to moderate acne vulgaris: a randomized control trial. [2009.05]

Tolerability of clindamycin/tretinoin gel vs. tretinoin microsphere gel and adapalene gel. [2009.04]

Association between statin use and risk for keratinocyte carcinoma in the veterans affairs topical tretinoin chemoprevention trial. [2009.01.06]

Gene mutations and response to treatment with all-trans retinoic acid in elderly patients with acute myeloid leukemia. Results from the AMLSG Trial AML HD98B. [2009.01]

Expression of retinoid-regulated genes in lamellar ichthyosis vs. healthy control epidermis: changes after oral treatment with liarozole. [2009]

Improvement of photoaged facial skin in middle-aged Japanese females by topical retinol (vitamin A alcohol): a vehicle-controlled, double-blind study. [2009]

Adapalene gel 0.1% is better tolerated than tretinoin gel 0.025% among healthy volunteers of various ethnic origins. [2009]

Modulation of plasma all-trans retinoic acid concentrations by the consumption of carotenoid-rich vegetables. [2008.11]

A randomized controlled trial of the efficacy and safety of a fixed triple combination (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) compared with hydroquinone 4% cream in Asian patients with moderate to severe melasma. [2008.09]

Analytic quantification of the bleaching effect of a 4-hydroxyanisole-tretinoin combination on actinic lentigines. [2008.09]

A novel gel formulation of clindamycin phosphate-tretinoin is not associated with acne flaring. [2008.08]

Comparative evaluation of beneficiary effects of priming agents (2% hydroquinone and 0.025% retinoic acid) in the treatment of melasma with glycolic acid peels. [2008.08]

A randomized controlled trial of the efficacy and safety of a fixed triple combination (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) compared with hydroquinone 4% cream in Asian patients with moderate to severe melasma. [2008.06.28]

Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial. [2008.04]

All-trans retinoic acid for treatment of chronic hepatitis C. [2008.03]

Pharmacokinetics and metabolism of all-trans- and 13-cis-retinoic acid in pulmonary emphysema patients. [2008.01]

Proliferative changes in the bronchial epithelium of former smokers treated with retinoids. [2007.11.07]

Effect of myristyl nicotinate on retinoic acid therapy for facial photodamage. [2007.11]

Community-based trial results of combination clindamycin 1%--benzoyl peroxide 5% topical gel plus tretinoin microsphere gel 0.04% or 0.1% or adapalene gel 0.1% in the treatment of moderate to severe acne. [2007.07]

Tretinoin gel microspheres 0.04% versus 0.1% in adolescents and adults with mild to moderate acne vulgaris: a 12-week, multicenter, randomized, double-blind, parallel-group, phase IV trial. [2007.06]

A comparison of low-dose cytarabine and hydroxyurea with or without all-trans retinoic acid for acute myeloid leukemia and high-risk myelodysplastic syndrome in patients not considered fit for intensive treatment. [2007.03.15]

[Application of all-trans retinoic acid combining chemotherapy and As4S4 in the maintenance treatment of patients with acute promyelocytic leukemia] [2007.01]

Tretinoin microsphere gel 0.1% for photodamaged facial skin: a placebo-controlled trial. [2006.12]

Feasibility of retinoids for the treatment of emphysema study. [2006.11]

Beneficial effect of a moisturizing cream as adjunctive treatment to oral isotretinoin or topical tretinoin in the management of acne. [2006.11]

Facilitating facial retinization through barrier improvement. [2006.10]

Cumulative irritancy comparison of topical retinoid and antimicrobial combination therapies. [2006.09]

Retinoic acid as a novel medical therapy for Cushing's disease in dogs. [2006.09]

Safety and efficacy of Tretin-X compared with Retin-A in patients with mild-to-severe acne vulgaris. [2006.05]

Is interferon-alpha and retinoic acid combination along with radiation superior to chemo-radiation in the treatment of advanced carcinoma of cervix? [2006.04]

Relapse of acute promyelocytic leukemia with PML-RARalpha mutant subclones independent of proximate all-trans retinoic acid selection pressure. [2006.04]

Two randomized, double-blind, controlled trials of 2219 subjects to compare the combination clindamycin/tretinoin hydrogel with each agent alone and vehicle for the treatment of acne vulgaris. [2006.01]

Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy. [2006.01]

'Keratolytic' properties of benzoyl peroxide and retinoic acid resemble salicylic acid in man. [2006]

The effect of short-contact topical tretinoin therapy for foot ulcers in patients with diabetes. [2005.11]

Comparison of clindamycin/benzoyl peroxide, tretinoin plus clindamycin, and the combination of clindamycin/benzoyl peroxide and tretinoin plus clindamycin in the treatment of acne vulgaris: a randomized, blinded study. [2005.09]

Novel approach to the treatment of hyperpigmented photodamaged skin: 4% hydroquinone/0.3% retinol versus tretinoin 0.05% emollient cream. [2005.07]

Exposure to retinoic acids in non-pregnant women following high vitamin A intake with a liver meal. [2005.05]

Cumulative irritation potential of adapalene 0.1% cream and gel compared with tretinoin microsphere 0.04% and 0.1%. [2005.04]

9-cis-retinoic acid treatment increases serum concentrations of alpha-tocopherol in former smokers. [2005.03.15]

Prevention of second primary tumors by an acyclic retinoid in patients with hepatocellular carcinoma. Updated analysis of the long-term follow-up data. [2005.01]

Long-term efficacy and safety of tretinoin emollient cream 0.05% in the treatment of photodamaged facial skin: a two-year, randomized, placebo-controlled trial. [2005]

Well-designed clinical trials possibly related to Retin-A (Tretinoin Topical)

AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance. [2011.05.05]

Instrumental analysis of the pattern of improvement and that of recurrence of melasma in Thai females treated with Kligman-Willis triple combination therapy: confirmation by using its two different formulae. [2011.05]

Nonablative 1550-nm fractional laser therapy versus triple topical therapy for the treatment of melasma: a randomized controlled pilot study. [2011.03]

Sequential treatment with triple combination cream and intense pulsed light is more efficacious than sequential treatment with an inactive (control) cream and intense pulsed light in patients with moderate to severe melasma. [2011.02]

Does microgranular variant morphology of acute promyelocytic leukemia independently predict a less favorable outcome compared with classical M3 APL? A joint study of the North American Intergroup and the PETHEMA Group. [2010.12.16]

Arsenic trioxide improves event-free and overall survival for adults with acute promyelocytic leukemia: North American Leukemia Intergroup Study C9710. [2010.11.11]

Non-ablative 1,550 nm fractional laser therapy versus triple topical therapy for the treatment of melasma: a randomized controlled split-face study. [2010.09]

Simplifying regimens promotes greater adherence and outcomes with topical acne medications: a randomized controlled trial. [2010.08]

Low-fluence Q-switched neodymium-doped yttrium aluminum garnet laser for melasma with pre- or post-treatment triple combination cream. [2010.06]

Favourable outcome of patients with childhood acute promyelocytic leukaemia after treatment with reduced cumulative anthracycline doses. [2010.05]

Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: results of the MRC AML12 trial. [2010.02.01]

Treatment of children with acute promyelocytic leukemia: results of the first North American Intergroup trial INT0129. [2009.12]

Consensus statement on the management of chronic hand eczema. [2009.10]

Effects of a cosmetic 'anti-ageing' product improves photoaged skin [corrected]. [2009.08]

Comparative evaluation of the efficacy of four topical medications individually or in combination to treat grade I acne vulgaris. [2009.04]

Association of ACE inhibitors and angiotensin receptor blockers with keratinocyte cancer prevention in the randomized VATTC trial. [2008.09.03]

Loss of elastic fibers causes skin wrinkles in sun-damaged human skin. [2008.05]

Reliability of the histopathologic diagnosis of keratinocyte carcinomas. [2007.08]

A randomized study with or without intensified maintenance chemotherapy in patients with acute promyelocytic leukemia who have become negative for PML-RARalpha transcript after consolidation therapy: the Japan Adult Leukemia Study Group (JALSG) APL97 study. [2007.07.01]

A hydroquinone formulation with increased stability and decreased potential for irritation. [2007.06]

A comparison of triple combination cream and hydroquinone 4% cream for the treatment of moderate to severe facial melasma. [2007.03]

Is cytarabine useful in the treatment of acute promyelocytic leukemia? Results of a randomized trial from the European Acute Promyelocytic Leukemia Group. [2006.12.20]

Regulation of cutaneous drug-metabolizing enzymes and cytoprotective gene expression by topical drugs in human skin in vivo. [2006.08]

Fludarabine and cytosine are less effective than standard ADE chemotherapy in high-risk acute myeloid leukemia, and addition of G-CSF and ATRA are not beneficial: results of the MRC AML-HR randomized trial. [2006.06.15]

A large 12-month extension study of an 8-week trial to evaluate the safety and efficacy of triple combination (TC) cream in melasma patients previously treated with TC cream or one of its dyads. [2005.09]

GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children. [2005.07.15]

Other research related to Retin-A (Tretinoin Topical)

Assessing the bioequivalence of topical retinoid products by pharmacodynamic assay. [2012]

Predictors of basal cell carcinoma in high-risk patients in the VATTC (VA Topical Tretinoin Chemoprevention) trial. [2012]

Efficacy and safety of clindamycin-tretinoin gel versus clindamycin or tretinoin alone in acne vulgaris: a randomized, double-blind, vehicle-controlled study. [2012]

Tretinoin and the prevention of keratinocyte carcinoma (Basal and squamous cell carcinoma of the skin): a veterans affairs randomized chemoprevention trial. [2012]

Comparative study of 5 % potassium hydroxide solution versus 0.05% tretinoin cream for Molluscum Contagiosum in children. [2011]

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