RETIN-A MICRO SUMMARY
RETIN-A MICRO® (tretinoin gel) microsphere, 0.1% and 0.04%
Retin-A Micro (tretinoin gel) microsphere, 0.1% and 0.04%, is a formulation containing 0.1% or 0.04%, by weight, tretinoin for topical treatment of acne vulgaris. This formulation uses patented methyl methacrylate/glycol dimethacrylate crosspolymer porous microspheres (MICROSPONGE® System) to enable inclusion of the active ingredient, tretinoin, in an aqueous gel. Other components of this formulation are purified water, carbomer 974P (0.04% formulation), carbomer 934P (0.1% formulation), glycerin, disodium EDTA, propylene glycol, sorbic acid, PPG-20 methyl glucose ether distearate, cyclomethicone and dimethicone copolyol, benzyl alcohol, trolamine, and butylated hydroxytoluene.
Retin-A Micro (tretinoin gel) microsphere, 0.1% and 0.04%, is indicated for topical application in the treatment of acne vulgaris. The safety and efficacy of the use of this product in the treatment of other disorders have not been established.
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RETIN-A MICRO NEWS HIGHLIGHTS Media Articles Related to Retin-A Micro (Tretinoin Topical)
Health Tip: Caring for Your Skin With Acne (HealthDay) Source: Y! Health Skin Conditions News [2008.11.26]
Acne Cream Recalled for Possible Bacterial Contamination Source: MedPage Today Dermatology [2008.11.17]
Study Lets Teens Sound Off on Acne Therapies Source: MedicineNet Acne Specialty [2008.08.19]
Acne (Pimples) Source: MedicineNet Boils Specialty [2008.07.16]
Acne Drug Prevents Tissue Damage From Emphysema Source: MedicineNet Acne Specialty [2008.05.16]
Published Studies Related to Retin-A Micro (Tretinoin Topical)
A novel gel formulation of clindamycin phosphate-tretinoin is not associated with acne flaring. [2008.08]
Efficacy and safety of oral alitretinoin (9-cis retinoic acid) in patients with severe chronic hand eczema refractory to topical corticosteroids: results of a randomized, double-blind, placebo-controlled, multicentre trial. [2008.04]
Community-based trial results of combination clindamycin 1%--benzoyl peroxide 5% topical gel plus tretinoin microsphere gel 0.04% or 0.1% or adapalene gel 0.1% in the treatment of moderate to severe acne. [2007.07]
Tretinoin gel microspheres 0.04% versus 0.1% in adolescents and adults with mild to moderate acne vulgaris: a 12-week, multicenter, randomized, double-blind, parallel-group, phase IV trial. [2007.06]
Cost-effectiveness of a fixed combination of hydroquinone/tretinoin/fluocinolone cream compared with hydroquinone alone in the treatment of melasma. [2007.02]
Clinical Trials Related to Retin-A Micro (Tretinoin Topical)
Study of Denufosol (INS37217) in Subjects With Rhegmatogenous Retinal Detachment [Terminated]
Comparison of Tazarotene and Minocycline Therapies for Maintenance of Facial Acne Vulgaris [Completed]
Pegaptanib Sodium Compared to Sham Injection in Patients With Recent Vision Loss Due to Macular Edema Secondary to Central Retinal Vein Occlusion (CRVO)
Clinical Evaluation of the Photoallergy Potential of Atralin Gel [Completed]
The Standard Care vs. COrticosteroid for REtinal Vein Occlusion (SCORE) Study [Active, not recruiting]
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RETIN-A MICRO PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 16 ratings/reviews, Retin-A Micro has an overall score of 7.75. The effectiveness score is 8.12 and the side effect score is 7.38. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Retin-A Micro review by 34 year old female patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Ineffective |
| Side effects: | | Mild Side Effects | | | Treatment Info |
| Condition / reason: | | acne |
| Dosage & duration: | | .1% (dosage frequency: daily) for the period of 3months |
| Other conditions: | | none |
| Other drugs taken: | | none | | | Reported Results |
| Benefits: | | None that I had experienced. |
| Side effects: | | Redness the first week. Then acne got worse. |
| Comments: | | Decided to stop treatment after three months. I was using it to get rid of small pimples on my forehead. After using the product, I noticed I was getting bigger, and bigger pimples. So I stopped. |
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| | Retin-A Micro review by 48 year old female patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Considerably Effective |
| Side effects: | | Mild Side Effects | | | Treatment Info |
| Condition / reason: | | Acne |
| Dosage & duration: | | .1% (dosage frequency: once a day at night) for the period of 5 years |
| Other conditions: | | Aging |
| Other drugs taken: | | Synthyroid, Advair | | | Reported Results |
| Benefits: | | Helped with clearing up my skin and keeping in clear. It also helped with fine lines around the eyes and mouth. |
| Side effects: | | At first my skin was very sensitive, dry and flaky. After approximately 4-6 weeks all the side effects disappeared, my face cleared and has stayed that way. It has however made my skin extremely sensitive to the sun. |
| Comments: | | After washing my face at night, I was to wait around 15 minutes before applying a small pea size amount all over my face and neck. |
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| | Retin-A Micro review by 49 year old male patient | | | Rating |
| Overall rating: | |           |
| Effectiveness: | | Highly Effective |
| Side effects: | | Mild Side Effects | | | Treatment Info |
| Condition / reason: | | acne |
| Dosage & duration: | | .1% micro gel (dosage frequency: 1x a day) for the period of 1 year |
| Other conditions: | | none |
| Other drugs taken: | | none | | | Reported Results |
| Benefits: | | reduced acne breakout, redness from breakout went away quickly, smoother skin |
| Side effects: | | flaking, sensitivity to acid products |
| Comments: | | Cleansed face am and pm. Pat skin dry. Used non-alcohol toner only in pm. Applied retin-a micro in the evening. Nothing else on top. Cleansed in the am and applied sunscreen with out chemicals-titanium dioxide based product. |
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