NEWS HIGHLIGHTSMedia Articles Related to Restoril (Temazepam)
Stress, Bad Bedtime Habits Cause Insomnia
Source: MedicineNet Sleep Aids And Stimulants Specialty [2009.07.27]
Title: Stress, Bad Bedtime Habits Cause Insomnia
Category: Health News
Created: 7/25/2009 7:00:00 AM
Last Editorial Review: 7/27/2009
Pills Plus Psychotherapy Can Beat Insomnia
Source: MedicineNet Sleep Aids And Stimulants Specialty [2009.05.20]
Title: Pills Plus Psychotherapy Can Beat Insomnia
Category: Health News
Created: 5/20/2009 2:00:00 AM
Last Editorial Review: 5/20/2009
Insomnia
Source: MedicineNet Biorhythms Specialty [2009.03.03]
Title: Insomnia
Category: Diseases and Conditions
Created: 6/6/2005
Last Editorial Review: 3/3/2009
Insomnia Treatment: Sleep Aids and Stimulants
Source: MedicineNet Narcolepsy Specialty [2009.01.14]
Title: Insomnia Treatment: Sleep Aids and Stimulants
Category: Diseases and Conditions
Created: 9/24/1999 7:06:00 AM
Last Editorial Review: 1/14/2009
Ten Tips to Avoid Insomnia and Get a Good Night's Sleep
Source: MedicineNet temazepam Specialty [2008.06.05]
Title: Ten Tips to Avoid Insomnia and Get a Good Night's Sleep
Category: Doctor's Views
Created: 6/14/2005
Last Editorial Review: 6/5/2008
Published Studies Related to Restoril (Temazepam)
Effects of 2-Week Treatment With Temazepam and Diphenhydramine in Elderly Insomniacs: A Randomized, Placebo-Controlled Trial. [2008.04]
A randomized, controlled, crossover clinical study compared 14-night treatment with 15 mg temazepam, 50 mg diphenhydramine, and placebo in elderly individuals with insomnia (mean age, 73.9 years; range, 70-89 years). Primary outcome measures were subjective assessments of sleep recorded on sleep diaries...
Temazepam at high altitude reduces periodic breathing without impairing next-day performance: a randomized cross-over double-blind study. [2006.12]
The aim of the study was to examine the efficacy and safety of temazepam on nocturnal oxygenation and next-day performance at altitude. A double-blind, randomized, cross-over trial was performed in Thirty-three healthy volunteers... We conclude that at high altitude temazepam is effective in reducing periodic breathing, and is safe to use, without any adverse effect upon next-day performance.
Usefulness of temazepam and zaleplon to induce afternoon sleep. [2006.10]
Insufficient daytime sleep may result in reduction of effectiveness and safety during overnight military missions. The usefulness of temazepam and zaleplon to optimize afternoon sleep and their effects on performance and alertness during a subsequent night shift were studied.
Selective effects of clonidine and temazepam on attention and memory. [2005.05]
The present study compared the effects of clonidine and temazepam on performance on a range of tasks aiming to assess the role of central noradrenergic mechanisms in cognitive function. Fifteen healthy volunteers (seven male, eight female), aged 18-25 years, took part in a five-period crossover study in which they received placebo, temazepam (15 and 30 mg) and clonidine (150 and 300 microg) by mouth in counterbalanced order in sessions at least 4 days apart...
Efficacy of temazepam in frequent users: a series of N-of-1 trials. [2005.04]
BACKGROUND: Benzodiazepines are frequently prescribed for sleep disturbances. However, benzodiazepines are associated with side effects, and may be ineffective when used for a prolonged period of time. OBJECTIVES: To investigate for individual patients whether placebo was as effective as temazepam, or whether 10 mg was as effective as 20 mg temazepam, and whether these results influenced their future temazepam use... CONCLUSION: The results regarding the efficacy of temazepam varied across patients. N-of-1 trials seem to be valuable in patients who are motivated to stop or reduce their temazepam use. They clearly demonstrate the efficacy of temazepam, and may give patients additional confidence to discontinue regular hypnotic use. The value of N-of-1 trials for patients who are less motivated is unclear, as the size of treatment effect does not seem to influence future hypnotic use.
Clinical Trials Related to Restoril (Temazepam)
Pars Plana Vitrectomy (PPV) Versus Preoperative Intravitreal Bevacizumab Plus PPV to Treat Diabetic Tractional Retinal Detachment (IBETRA) [Completed]
The purpose of this study is to compare the amount of intraoperative intraocular bleeding
during 23-gauge pars plana vitrectomy (PPV) for diabetic traction retinal detachment (TRD)
with and without preoperative intravitreal bevacizumab treatment.
Effects of Temazepam in Patients With Chronic Pulmonary Obstructive Disease [Completed]
The purpose of this study is to evaluate the effects of temazepam during sleep and in daytime
on dyspnea, gas exchange and sleep quality in patients with chronic obstructive pulmonary
disease.
The study hypothesis is that temazepam does not produce any adverse respiratory effects
during sleep in patients with COPD. In contrast, it may result in an beneficiary effect
because it positively affects the sleep quality and sleep structure which may result in more
alertness and less daytime sleepiness and less dyspnea during the day.
Study to Investigate the Effects of Melatonin, Temazepam & Zolpidem on Sleep EEG in Men and Women [Recruiting]
This study has been designed to compare the effects of melatonin with those of drugs
(temazepam and zolpidem) regularly prescribed for the treatment of insomnia, in healthy,
middle-aged volunteers.
The study will take place at one centre. Volunteers consenting to participate in the study
will have their eligibility confirmed by a screening panel, including spending one night in
the sleep clinic to acclimatize to the study procedures. Blood and urine samples will be
collected during this overnight visit.
Volunteers continuing to remain eligible will receive, in turn, melatonin, temazepam,
zolpidem and placebo as a single dose during 4 treatment phases lasting one night and
separated by at least five days. Neither the volunteer nor the study staff will be aware of
which drug each volunteer is receiving at each treatment phase.
The volunteer's electrical brain activity will be measured whilst sleeping. Other aspects
of sleep, including measures of sleep quality, will also be measured. Urine samples will be
collected during each treatment phase.
Volunteers will undergo an assessment of health prior to departure from the clinic at their
last treatment phase, and study staff will telephone 2 weeks later to obtain further
information on their health status.
The primary study objective is to compare EEG power spectra during nonREM sleep in the
slow-wave frequencies following administration with melatonin to temazepam.
20- Versus 23- Gauge System for Pars Plana Vitrectomy [Completed]
The aim of the present study is to compare the functional and clinical differences and
advantages between a standard operating system and a newly developed even smaller system for
pars plana vitrectomy.
The present study may work out the possible advantages and disadvantages between the
routinely used 20-gauge vitrectomy system and the newly developed 23-gauge device.
Preoperative Bevacizumab for Vitreous Hemorrhage [Recruiting]
The purpose of this study is to determine whether preoperative intravitreal bevacizumab is
effective in reducing intra-operative and postoperative bleeding in diabetic patients
submitted to pars plana vitrectomy for vitreous hemorrhage.
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