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Reserpine (Reserpine) - Indications and Dosage



Mild essential hypertension; also useful as adjunctive therapy with other antihypertensive agents in the more severe forms of hypertension; relief of symptoms in agitated psychotic states (e.g., schizophrenia), primarily in those individuals unable to tolerate phenothiazine derivatives or in those who also require antihypertensive medication.



In the average patient not receiving other antihypertensive agents, the usual initial dosage is 0.5 mg daily for 1 or 2 weeks., For maintenance, reduce to 0.1-0.25 mg daily. Higher dosages should be used cautiously, because occurrence of serious mental depression and other side effects may increase considerably.

Psychiatric Disorders

The usual initial dosage is 0.5 mg daily, but may range from 0.1 mg to 1.0 mg. Adjust dosage upward or downward according to the patient's response.


Reserpine is not recommended for use in children (see PRECAUTIONS: Pediatric Use). If it is to be used in treating a child, the usual recommended starting dose is 20 µg/kg daily. The maximum recommended dose is 0.25 mg (total) daily.


Reserpine Tablets, USP for oral administration are available as:

0.1 mg: round, white, scored tablets, debossed SZ 71 on one side and plain on the reverse side and supplied as:

NDC 0185-0032-01 bottles of 100

NDC 0185-0032-10 bottles of 1000

0.25 mg: round, white, scored tablets, debossed SZ 77 on one side and plain on the reverse side and supplied as:

NDC 0185-0134-01 bottles of 100

NDC 0185-0134-10 bottles of 1000


Store at 20°-25°C (68°-77°F) [see USP Controlled Room Temperature]. Protect from moisture.

Preserve in tight, light-resistant containers.



Sandoz Inc.

Princeton, NJ 08540

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