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Relpax (Eletriptan Hydrobromide) - Summary

 
 



RELPAX SUMMARY

RELPAX® (eletriptan hydrobromide) Tablets

RELPAX® (eletriptan) Tablets contain eletriptan hydrobromide, which is a selective 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptor agonist.

RELPAX is indicated for the acute treatment of migraine with or without aura in adults.

RELPAX is not intended for the prophylactic therapy of migraine or for use in the management of hemiplegic or basilar migraine (see CONTRAINDICATIONS). Safety and effectiveness of RELPAX Tablets have not been established for cluster headache, which is present in an older, predominantly male population.


See all Relpax indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Relpax (Eletriptan)

Link found between migraine and Parkinson's
Source: Headache / Migraine News From Medical News Today [2014.09.18]
New research has found there may be an association with migraine in middle age and the development of Parkinson’s disease later in life.

Are Migraines in Middle Age Tied to Raised Parkinson's Risk Later?
Source: MedicineNet Tremor Specialty [2014.09.18]
Title: Are Migraines in Middle Age Tied to Raised Parkinson's Risk Later?
Category: Health News
Created: 9/17/2014 4:36:00 PM
Last Editorial Review: 9/18/2014 12:00:00 AM

Migraine sufferers may find meditation helps
Source: Headache / Migraine News From Medical News Today [2014.09.12]
A small study finds migraine sufferers who learned and practiced mindfulness-based stress reduction had fewer, less severe headaches than those who received standard care.

Cosmetic eyelid surgery technique effective for migraine relief
Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today [2014.08.04]
Dr. Oren Tessler, Assistant Professor of Clinical Surgery at LSU Health Sciences Center New Orleans School of Medicine, is part of a team of plastic and reconstructive surgeons who report a high...

Symptom relief following non-endoscopic migraine surgery
Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today [2014.07.31]
A revised version of a surgical procedure to treat severe chronic migraine headaches led to significant symptom relief more than 90 percent of the time in patients treated at Massachusetts General...

more news >>

Published Studies Related to Relpax (Eletriptan)

Efficacy of eletriptan in triptan-naive patients: results of a combined analysis. [2007.02]
OBJECTIVE: To compare the efficacy and tolerability of eletriptan 20 mg, 40 mg, and 80 mg in triptan-naive patients (who have not previously used triptans) versus triptan-experienced patients (who have previously used triptans)... CONCLUSIONS: These data suggest that eletriptan has comparable efficacy versus placebo among both triptan-naive and triptan-experienced patients.

Preference for rizatriptan 10-mg wafer vs. eletriptan 40-mg tablet for acute treatment of migraine. [2006.03]
Preference is a composite, patient-oriented endpoint incorporating efficacy, tolerability, formulation, and convenience of medications. The objective of this study was to compare patient preference for rizatriptan 10-mg wafer vs... The single most important reason for preference was speed of relief, consistent with results from previous preference studies.

Eletriptan in the early treatment of acute migraine: influence of pain intensity and time of dosing. [2005.09]
This double-blind, placebo-controlled study was designed to evaluate the efficacy and tolerability of early treatment of a single migraine attack, when headache pain was mild, with two doses (20 mg and 40 mg) of eletriptan. Patients (N = 613; female 79%; mean age 39 years) meeting International Headache Society criteria for migraine were encouraged, but not required, to utilize early treatment, thus providing an opportunity to assess the relative contribution to efficacy of pain severity and timing of dose...

Patient preference for eletriptan 80 mg versus subcutaneous sumatriptan 6 mg: results of a crossover study in patients who have recently used subcutaneous sumatriptan. [2005.02]
This current randomized, open-label, crossover study evaluated preference for oral eletriptan 80 mg compared with subcutaneous sumatriptan 6 mg (suma-sc) amongst patients (n = 311) meeting IHS criteria for migraine who had recently used suma-sc, and found it well tolerated... The results of this study suggest that eletriptan is a strong alternative option for patients who have been prescribed suma-sc.

No effect of eletriptan administration during the aura phase of migraine. [2004.10]
Migraine aura is a warning sign readily recognized by patients... This study confirms the findings of two studies showing that triptans are ineffective but safe when given during the migraine aura phrase.

more studies >>

Clinical Trials Related to Relpax (Eletriptan)

TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine [Completed]

A Trial to Study of the Effects of Eletriptan 40mg on Mild vs Moderate to Severe Pain Intensity of Migraine [Completed]
To evaluate the efficacy of early intervention (dosing within 2 hours of onset of the migraine attack) with eletriptan 40mg on mild versus moderate to severe pain intensity of migraine.

Prospective Survey of Menstrual Migraine & Prevention With Eletriptan [Recruiting]
Women are followed prospectively for 3 months, recording headaches, other symptoms, and menstrual periods. Those with menstrual migraine are treated perimenstrually with eletriptan for 3 months.

Efficacy and Safety of Eletriptan for the Treatment of Migraine in Patients Not Satisfied With Rizatriptan Therapy [Completed]
To assess the efficacy and safety of eletriptan for migraine headaches in subjects who were not satisfied with rizatriptan therapy

Safety and Efficacy of Eletriptan for the Treatment of Migraine in Subjects Unsuccessfully Treated With Nonsteroidal Anti-Inflammatory Drugs [Completed]
To assess the safety and efficacy of eletriptan for the treatment of migraine in subjects who had not been adequately treated with non-steroidal antiinflammatory drugs (NSAIDs)

more trials >>

Reports of Suspected Relpax (Eletriptan) Side Effects

Drug Ineffective (49)Headache (47)Migraine (47)Feeling Abnormal (17)Depression (15)Chest Discomfort (13)Nausea (11)Fatigue (10)Vomiting (10)Pain in Extremity (9)more >>


PATIENT REVIEWS / RATINGS / COMMENTS

Based on a total of 6 ratings/reviews, Relpax has an overall score of 8. The effectiveness score is 8 and the side effect score is 8.33. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
 

Relpax review by 47 year old female patient

  Rating
Overall rating:  
Effectiveness:   Highly Effective
Side effects:   No Side Effects
  
Treatment Info
Condition / reason:   migraine relief
Dosage & duration:   25mg taken 4x/month for the period of 3 years
Other conditions:   n/a
Other drugs taken:   n/a
  
Reported Results
Benefits:   migraine pain relieved in 1 - 2 hours and lasted for 24 hours with 1 tablet
Side effects:   none
Comments:   1 tablet at first signs of headache

 

Relpax review by 40 year old female patient

  Rating
Overall rating:  
Effectiveness:   Considerably Effective
Side effects:   Mild Side Effects
  
Treatment Info
Condition / reason:   Migraines
Dosage & duration:   can't remember (dosage frequency: 1 every 24 hrs as needed for migraine) for the period of once a month
Other conditions:   n/a
Other drugs taken:   Pristiq
  
Reported Results
Benefits:   It would ease the throbbing feeling associated with a migraine.
Side effects:   Low blood pressure.
Comments:   You could feel a marked difference in your blood pressure, that was the only negative side effect. Other than that, it helped calm the pulsating sensation you would get with an intense migraine. Helping you to relax and feel better.

 

Relpax review by 39 year old female patient

  Rating
Overall rating:  
Effectiveness:   Marginally Effective
Side effects:   Moderate Side Effects
  
Treatment Info
Condition / reason:   migraine headaches
Dosage & duration:   .5 (dosage frequency: 2 times per day) for the period of 3 days
Other conditions:   none
Other drugs taken:   birth control
  
Reported Results
Benefits:   The medication took almost thirty minutes to kick in. Once the medication started to take affect, I began to develop a tingling sensation in my left hand and later my right hand. I also noticed my hands were very shaky after the medication was in my system for at least an hour.
Side effects:   The medication took almost thirty minutes to kick in. Once the medication started to take affect, I began to develop a tingling sensation in my left hand and later my right hand. I also noticed my hands were very shaky after the medication was in my system for at least an hour.
Comments:   Once a migraine is formulating, one pill is to be taken. The medication took almost thirty minutes to kick in. Once the medication started to take affect, I began to develop a tingling sensation in my left hand and later my right hand. I also noticed my hands were very shaky after the medication was in my system for at least an hour.

See all Relpax reviews / ratings >>

Page last updated: 2014-09-18

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