Regitine (Phentolamine Mesylate) - Summary

REGITINE SUMMARY

Regitine^®

Regitine, phentolamine mesylate for injection, USP, is an antihypertensive, available in vials for intravenous and intramuscular administration.

Regitine is indicated for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.

Regitine is indicated for the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine.

Regitine is also indicated for the diagnosis of pheochromocytoma by the Regitine blocking test.

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REGITINE NEWS HIGHLIGHTS

Published Studies Related to Regitine (Phentolamine)

Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patients. [2008.08]

Reversal of soft-tissue local anesthesia with phentolamine mesylate in adolescents and adults. [2008.08]

Pharmacokinetics of lidocaine with epinephrine following local anesthesia reversal with phentolamine mesylate. [2008.06]

Injection therapy for the treatment of erectile dysfunction: a comparison between alprostadil and a combination of vasoactive intestinal polypeptide and phentolamine mesilate. [2007.10]

Assessment of the efficacy of phentolamine to prevent radial artery spasm during cardiac catheterization procedures: a randomized study comparing phentolamine vs. verapamil. [2005.10]

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Clinical Trials Related to Regitine (Phentolamine)

The Effect of Alfa-Adrenergic Receptor Blockade on Insulin-Stimulated Forearm Glucose Uptake and Metabolism in Chronic Heart Failure [Recruiting]

Nerve-Sparing Radical Prostatectomy With or Without Nerve Grafting Followed by Standard Therapy for Erectile Dysfunction in Treating Patients With Localized Prostate Cancer [Active, not recruiting]

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage [Completed]

Study of NV-101 for Safety and Efficacy in Pediatric Dental Patients Undergoing Procedures [Completed]

Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures [Completed]

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