REBIF SUMMARY
Rebif® (interferon beta-1a) is a purified 166 amino acid glycoprotein with a molecular weight of approximately 22,500 daltons.
Rebif® (interferon-beta-1a) is indicated for the treatment of patients with relapsing forms of multiple sclerosis to decrease the frequency of clinical exacerbations and delay the accumulation of physical disability. Efficacy of Rebif® in chronic progressive multiple sclerosis has not been established.
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REBIF NEWS HIGHLIGHTS
Published Studies Related to Rebif (Interferon Beta-1A)
Interferon Beta 1a versus Interferon Beta 1a plus Ribavirin for the Treatment of Chronic Hepatitis C in Chinese Patients: A Randomized, Placebo-Controlled Trial. [2008.08]
Clinical trial: a multicentre, randomized, double-blind, placebo-controlled, dose-finding, phase II study of subcutaneous interferon-beta-1a in moderately active ulcerative colitis. [2008.06.21]
Interferon Beta 1a versus Interferon Beta 1a plus Ribavirin for the Treatment of Chronic Hepatitis C in Chinese Patients: A Randomized, Placebo-Controlled Trial. [2007.12.13]
Cytokine changes during interferon-beta therapy in multiple sclerosis: correlations with interferon dose and MRI response. [2007.04]
Long-term subcutaneous interferon beta-1a therapy in patients with relapsing-remitting MS. [2006.09.26]
Clinical Trials Related to Rebif (Interferon Beta-1A)
Rebif New Formulation (RNF) Quality of Life Study [Active, not recruiting]
Study to Determine if Avonex and Rebif Work Comparably Well in Subjects With Relapsing Multiple Sclerosis [Completed]
Transition to Rebif New Formulation [Active, not recruiting]
Avonex (Interferon-Beta-1a) and Avonex Plus Methylprednisolone for the Treatment of Relapsing-Remitting MS [Active, not recruiting]
Phase II Cladribine Add-on to Inteferon-Beta (IFN-b) Therapy in MS Subjects With Active Disease [Recruiting]
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REBIF PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 1 ratings/reviews, Rebif has an overall score of 6. The effectiveness score is 8 and the side effect score is 6. The scores are on ten point scale: 10 - best, 1 - worst.
| | Rebif review by 29 year old female patient | | | Rating |
| Overall rating: | |   |
| Effectiveness: | | Considerably Effective |
| Side effects: | | Moderate Side Effects | | |
Treatment Info |
| Condition / reason: | | Multiple Sclerosis |
| Dosage & duration: | | 250 mg taken 3x weekly for the period of 18 months |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | Reduce number of MS relapses |
| Side effects: | | Flu like symptoms- aches, fever |
| Comments: | | subcutaneous injection 3x weekly |
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Page last updated: 2008-08-10
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