REBETOL® Capsules and Oral Solution may cause birth defects and/or death of the exposed fetus. REBETOL therapy is contraindicated for use in women who are pregnant or in men whose female partners are pregnant (see WARNINGS and PRECAUTIONS, Information for Patients and Pregnancy Category X sections).
REBETOL Capsules and Oral Solution are contraindicated in patients with a history of hypersensitivity to ribavirin or any component of the capsule.
Patients with autoimmune hepatitis must not be treated with combination REBETOL/INTRON A therapy because using these medicines can make the hepatitis worse.
Patients with hemoglobinopathies (e.g., thalassemia major, sickle-cell anemia) should not be treated with REBETOL Capsules or Oral Solution.