DRUG INTERACTIONS
No formal drug interaction studies have been per-formed with RAPTIVA. RAPTIVA should not be used with other immunosuppressive drugs (see PRECAUTIONS, Immunosuppression).
Acellular, live and live-attenuated vaccines should not be administered during RAPTIVA treatment (see PRECAUTIONS, Immunizations).
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OVERDOSAGE
Doses up to 4 mg/kg/wk SC for 10 weeks following a conditioning (0.7 mg/kg) first dose have been administered without an observed increase in acute toxicity. The maximum administered single dose was 10 mg/kg IV. This was administered to one patient, who subsequently was admitted to the hospital for severe vomiting. In case of overdose, it is recommended that the patient be monitored for 24-48 hours for any acute signs or symptoms of adverse reactions or effects and appropriate treatment instituted.
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