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Rapamune (Sirolimus) - Current Clinical Trials

 
 



Rapamune Related Clinical Trials

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects [Completed]

Study Evaluating Sirolimus in Kidney Transplant Recipients. [Completed]

Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM [Active, not recruiting]

Study Evaluating Sirolimus (Rapamuneâ„¢) in Solid Organ Transplant Recipients [Active, not recruiting]

Study of Combination of Sirolimus and Sutent in Patients With Advanced Solid Tumors Non-Curable With Standard Therapy [Active, not recruiting]

Rapamycin+Estradiol- vs. Rapamycin-Eluting Stents to Reduce Restenosis (ISAR-PEACE) [Completed]

Trial of Sirolimus and Methotrexate in Relapsed/Refractory Lymphoblastic Leukemia and Lymphoma [Recruiting]

Docetaxel and Sirolimus in Patients With Advanced Malignancies [Recruiting]

Chronic Graft-versus-Host Disease Treatment (BMT CTN 0801) [Recruiting]

Rapamycin and Regulatory T Cells in Kidney Transplantation [Recruiting]

Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant Recipients [Completed]

A Open Label Clinical Trial of Continuous Once Daily Oral Treatment Using BIBW 2992 Plus Sirolimus (Rapamune®) in Patients With Non-small Cell Lung Cancer Harbouring an EGFR Mutation and/or Disease Progression Following Prior Erlotinib (Tarceva®) [Recruiting]

Study of Vinblastine and Sirolimus in Pediatric Patients With Recurrent or Refractory Solid Tumors Including Central Nervous System Tumors [Recruiting]

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1) [Recruiting]

Rapamycin in Combination With Low-Dose Aracytin in Elderly Acute Myeloid Leukemia Patients [Completed]

Sirolimus Conversions in African-American Renal Transplant Recipients [Recruiting]

A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas [Recruiting]

Sirolimus and Pemetrexed to Treat Non-Small Cell Lung Cancer [Recruiting]

Drug Interaction Study of Sorafenib and Rapamycin in Advanced Malignancies [Suspended]

Randomized Conversion of Calcineurin-Inhibitors in Renal Allograft Recipients [Recruiting]

Rapamycin in Relapsed Acute Lymphoblastic Leukemia [Recruiting]

Study of Sirolimus With PEG-Asparaginase in Acute Lymphoblastic Leukemia (ALL) [Recruiting]

Study to Compare the Safety and Efficacy of Sirolimus (Rapamune) to Tacrolimus (Advagraf) Associated to Mycophenolate Mofetil (CellCept) Between 12 and 36 Months After Kidney Transplantation [Recruiting]

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets [Active, not recruiting]

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients [Active, not recruiting]

Study Evaluating Conversion From Tacrolimus to Sirolimus in Stable Kidney Transplant Recipients Receiving Myfortic [Recruiting]

Study Comparing Standard Dose and Reduced Dose Tacrolimus With Sirolimus in Renal Transplant Patients [Completed]

A Safety Study of LBH589 (Panobinostat) and RAD001 (Everolimus) to Stabilize Kidney Cancer [Recruiting]

A Pilot Study Evaluating the Use of mTor Inhibitor Sirolimus in Children and Young Adults With Desmoid-Type Fibromatosis [Recruiting]

A Study of Temsirolimus Plus Capecitabine in Patients With Advanced Cancer [Recruiting]

Treating Multiple Sclerosis With Sirolimus, an Immune System Suppressor [Completed]

Torisel in Addition to Standard Chemotherapy With Radiation for Advanced Head and Neck Cancer [Recruiting]

Trial to Evaluate Paclitaxel Plus RAD001 in Urothelial Carcinoma [Recruiting]

Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer [Recruiting]

A Phase II Study of Rapamycin and Trastuzumab for Patients With HER-2 Receptor Positive Metastatic Breast Cancer [Recruiting]

Rapamycin-Eluting Stents With Different Polymer Coating to Reduce Restenosis (ISAR-TEST-3) [Completed]

Prospective Study of Rapamycin for the Treatment of SLE [Recruiting]

Study of RAD001 (Everolimus) for Children With NF1 and Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas [Recruiting]

Dose Finding Study of RAD001 (Everolimus, Afinitor�) in Combination With BEZ235 in Patients With Advanced Solid Tumors [Recruiting]

Vemurafenib in Combination With Everolimus or Temsirolimus With Advanced Cancer [Recruiting]

A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid Cancers [Recruiting]

Study of (1) Everolimus, (2) Estrogen Deprivation Therapy (EDT) With Leuprolide + Letrozole and (3) Everolimus + EDT in Patients With Unresectable Fibrolamellar Hepatocellular Carcinoma (FLL-HCC) [Recruiting]

BNC105P in Combination With Everolimus/Following Everolimus For Progressive Metastatic Clear Cell Renal Cell Carcinoma [Recruiting]

Trial of RAD001 and Neurocognition in Tuberous Sclerosis Complex (TSC) [Recruiting]

Everolimus Beyond Progress for Patients Who Had Progress Under Everolimus and Exemestane [Not yet recruiting]

Everolimus, Bortezomib and/or Rituximab in Patients With Relapsed/Refractory Waldenstrom's Macroglobulinemia [Recruiting]

STORM: Temsirolimus, Rituximab and DHAP for Relapsed and Refractory Diffuse Large B-cell Lymphoma [Not yet recruiting]

Efficacy of RAD001/Everolimus in Autism and NeuroPsychological Deficits in Children With Tuberous Sclerosis Complex [Not yet recruiting]

Sirolimus for Autoimmune Disease of Blood Cells [Recruiting]

Randomized Phase I/II of RAD001 in Advanced Hepatocellular Carcinoma (HCC) [Recruiting]

Sirolimus as Therapeutic Approach to Uveitis [Recruiting]

Erlotinib and Temsirolimus for Solid Tumors [Recruiting]

Anakinra or Denosumab and Everolimus in Advanced Cancer [Recruiting]

A Study of mTOR Inhibitor Everolimus (RAD001) in Association With Cisplatin and Radiotherapy for Locally Advanced Cervix Cancer [Recruiting]

Everolimus Rescue Immunosuppression in the Treatment of Chronic Allograft Dysfunction in Renal Transplant Recipients [Recruiting]

Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults [Active, not recruiting]

Randomized Study of Oral Rapamycin Plus Bare Metal Stents [Completed]

Study Evaluating Rapamune in Patients After Kidney Transplantation

Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients [Terminated]

Campath-1H/Tacrolimus/Sirolimus Withdrawal in Renal Transplantation [Active, not recruiting]

Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia [Active, not recruiting]

Double or Single Dose Sirolimus-Eluting Stents in Diabetic Patients With de Novo Coronary Artery Lesions [Active, not recruiting]

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients [Active, not recruiting]

Sirolimus-Eluting Stents for Chronic Total Coronary Occlusions [Completed]

Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant Recipients [Completed]

Study Comparing Cyclosporin Dose Reduction With Cyclosporin Elimination in Kidney Transplant Recipients Taking Sirolimus [Completed]

Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure [Active, not recruiting]

Interaction Study of Rapamycin and Sunitinib in Patients With Advanced Cancers [Completed]

Sirolimus for Focal Segmental Glomerulosclerosis

Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft Recipients

A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model [Not yet recruiting]

Study Evaluating Sirolimus in Kidney Transplant Recipients in India [Completed]

Dose Ranging Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Diabetic Macular Edema [Recruiting]

Pemetrexed and Sirolimus in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer [Recruiting]

Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors [Recruiting]

Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration [Recruiting]

Sirolimus in Combination With MEC in High Risk Myeloid Leukemias [Recruiting]

Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration [Recruiting]

Sirolimus and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis in Myeloablative Matched Related Donor Hematopoietic Cell Transplant [Active, not recruiting]

Rapamycin Plus Bevacizumab in Advanced Cancers [Recruiting]

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus [Active, not recruiting]

Rapamycin Vs Methotrexate in Diffuse SSc [Active, not recruiting]

Thymoglobulin, Sirolimus and Mycophenolate Mofetil for Prevention of Acute Graft-Versus-Host Disease (GVHD) [Recruiting]

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell Transplantation [Completed]

Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-Myeloablative Peripheral Blood Stem Cell Transplantation [Active, not recruiting]

Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation [Completed]

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation [Completed]

Rapamycin in Advanced Cancers [Recruiting]

Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD). [Recruiting]

Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme [Recruiting]

Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma [Recruiting]

Rapamycin for Prevention of Chronic Graft-Versus-Host Disease [Recruiting]

TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients [Recruiting]

Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma [Recruiting]

Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression [Recruiting]

Study of Rapamycin Plus Ketoconazole in Advanced Cancers [Recruiting]

Sirolimus to Treat Diabetic Macular Edema [Recruiting]

Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation [Recruiting]

Rapamycin With Grapefruit Juice for Advanced Malignancies [Recruiting]

A Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantation [Recruiting]

A Phase I Study of SUNITINIB and Rapamycin in Advanced Non-Small Cell Lung Cancer (NSCLC) [Recruiting]

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