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Rapamune (Sirolimus) - Current Clinical Trials

 


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Rapamune Related Clinical Trials

Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects [Completed]

Study Evaluating Sirolimus in Kidney Transplant Recipients. [Completed]

Trial of Efficacy and Safety of Sirolimus in Tuberous Sclerosis and LAM [Active, not recruiting]

Study Evaluating Sirolimus (Rapamuneā„¢) in Solid Organ Transplant Recipients [Active, not recruiting]

Study of Combination of Sirolimus and Sutent in Patients With Advanced Solid Tumors Non-Curable With Standard Therapy [Active, not recruiting]

Rapamycin+Estradiol- vs. Rapamycin-Eluting Stents to Reduce Restenosis (ISAR-PEACE) [Completed]

Study Comparing Sirolimus/Prograf vs Sirolimus/CsA in High-Risk Renal Transplant Recipients [Completed]

Rapamycin in Combination With Low-Dose Aracytin in Elderly Acute Myeloid Leukemia Patients [Completed]

Drug Interaction Study of Sorafenib and Rapamycin in Advanced Malignancies [Suspended]

Sirolimus Blood Concentrations on Conversion From Oral Solution to Tablets [Active, not recruiting]

The Pharmacokinetics of Sirolimus When Combined With Cyclosporine or Tacrolimus in Renal Transplant Patients [Active, not recruiting]

Study Comparing Standard Dose and Reduced Dose Tacrolimus With Sirolimus in Renal Transplant Patients [Completed]

Treating Multiple Sclerosis With Sirolimus, an Immune System Suppressor [Completed]

Rapamycin-Eluting Stents With Different Polymer Coating to Reduce Restenosis (ISAR-TEST-3) [Completed]

Combination Immunosuppressive Therapy to Prevent Kidney Transplant Rejection in Adults [Active, not recruiting]

Randomized Study of Oral Rapamycin Plus Bare Metal Stents [Completed]

Study Evaluating Rapamune in Patients After Kidney Transplantation

Heart Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Heart Transplant Recipients [Terminated]

Campath-1H/Tacrolimus/Sirolimus Withdrawal in Renal Transplantation [Active, not recruiting]

Improving Immunosuppressive Treatment for Patients With Severe Aplastic Anemia [Active, not recruiting]

Double or Single Dose Sirolimus-Eluting Stents in Diabetic Patients With de Novo Coronary Artery Lesions [Active, not recruiting]

Study Evaluating of Calcineurin Inhibitor and Sirolimus (Rapamune) Treatment in Liver Transplant Recipients [Active, not recruiting]

Sirolimus-Eluting Stents for Chronic Total Coronary Occlusions [Completed]

Study Evaluating Sirolimus and Cyclosporine in Kidney Transplant Recipients [Completed]

Study Comparing Cyclosporin Dose Reduction With Cyclosporin Elimination in Kidney Transplant Recipients Taking Sirolimus [Completed]

Mycophenolate Mofetil and Rapamycin as Secondary Intervention vs. Continuation of Calcineurin Inhibitors in Patients at Risk for Chronic Renal Allograft Failure [Active, not recruiting]

Interaction Study of Rapamycin and Sunitinib in Patients With Advanced Cancers [Completed]

Sirolimus for Focal Segmental Glomerulosclerosis

Study Comparing Standard Dose and Reduced Dose Tacrolimus + Sirolimus + Corticosteroids in Renal Allograft Recipients

A Study of the mTOR Inhibitor Rapamycin (Rapamune, Sirolimus) in Combination With Abraxane in Advanced Solid Cancers [Recruiting]

A Phase II Study of Rapamycin and Trastuzumab for Patients With HER-2 Receptor Positive Metastatic Breast Cancer [Recruiting]

Sirolimus in Autoimmune Lymphoproliferative Syndrome: A Pilot Series [Recruiting]

Dose Ranging Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Diabetic Macular Edema [Recruiting]

Study Evaluating Sirolimus in Kidney Transplant Recipients in India [Completed]

Prospective Study of Rapamycin for the Treatment of SLE [Recruiting]

Pemetrexed and Sirolimus in Treating Patients With Relapsed or Refractory Non-Small Cell Lung Cancer [Recruiting]

Sirolimus in Combination With MEC in High Risk Myeloid Leukemias [Recruiting]

Phase 1/2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Patients With Age-Related Macular Degeneration [Recruiting]

Phase 2 Study of an Ocular Sirolimus (Rapamycin) Formulation in Combination With Lucentis® in Patients With Age-Related Macular Degeneration [Not yet recruiting]

Sirolimus in Treating Patients With Metastatic or Unresectable Solid Tumors [Recruiting]

A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas [Not yet recruiting]

Sirolimus and Mycophenolate Mofetil as Graft Versus Host Disease Prophylaxis in Myeloablative Matched Related Donor Hematopoietic Cell Transplant [Active, not recruiting]

Study of Unrelated Cord Blood Transplantation Using Tacrolimus and Sirolimus [Active, not recruiting]

Rapamycin Vs Methotrexate in Diffuse SSc [Active, not recruiting]

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Related Stem Cell Transplantation [Completed]

Thymoglobulin, Sirolimus and Mycophenolate Mofetil for Prevention of Acute GVHD [Recruiting]

Tacrolimus and Sirolimus as Prophylaxis After Allogenic Non-Myeloablative Peripheral Blood Stem Cell Transplantation [Active, not recruiting]

Ph II Erlotinib + Sirolimus for Pts w Recurrent Malignant Glioma Multiforme [Recruiting]

Tacrolimus, Sirolimus and Methotrexate as Graft Versus Host Disease Prophylaxis After Blood Stem Cell Transplantation [Completed]

Sirolimus With Tacrolimus for Graft-vs-Host Disease Prophylaxis After Un-Related Stem Cell Transplantation [Completed]

Study Evaluating Conversion From Tacrolimus to Sirolimus in Stable Kidney Transplant Recipients Receiving Myfortic [Recruiting]

Rapamycin in Advanced Cancers [Recruiting]

Sirolimus (Rapamune®) for Autosomal Dominant Polycystic Kidney Disease (ADPKD). [Recruiting]

Rapamycin for Prevention of Chronic Graft-Versus-Host Disease [Recruiting]

TUMORAPA 1: Efficacy of Rapamycin in Secondary Prevention of Skin Cancers in Kidney Transplant Recipients [Recruiting]

Erlotinib and Sirolimus for the Treatment of Metastatic Renal Cell Carcinoma [Recruiting]

Pediatric Kidney Transplant Study of Sirolimus, Mycophenolate Mofetil, and Corticosteroids vs Calcineurin Inhibitor Based Immunosuppression [Not yet recruiting]

A Phase II Study of Oral Cyclophosphamide and Sirolimus (OCR) in Advanced Sarcoma [Recruiting]

Study of Rapamycin Plus Ketoconazole in Advanced Cancers [Recruiting]

Sirolimus to Treat Diabetic Macular Edema [Recruiting]

Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation [Not yet recruiting]

Sirolimus in Treating Patients With HIV-Related Kaposi's Sarcoma [Recruiting]

A Phase I Study Using Tacrolimus, Sirolimus and Bortezomib as Acute Graft Versus Host Disease (GVHD) Prophylaxis in Allogeneic Peripheral Blood Stem Cell (PBSC) Transplantation [Recruiting]

Rapamycin With Grapefruit Juice for Advanced Malignancies [Recruiting]

A Phase I Study of SUNITINIB and Rapamycin in Advanced Non-Small Cell Lung Cancer (NSCLC) [Recruiting]

Study Evaluating Rapamune in Transplant Recipients in the Nordic Countries [Recruiting]

Safety Study of Rapamycin Administered Before and During Radiotherapy to Treat Rectum Cancer [Recruiting]

Sirolimus, Tacrolimus and Short Course Methotrexate for Prevention of Acute GVHD in Recipients of Mismatched Unrelated Donor Allogeneic Stem Cell Transplantation [Recruiting]

Rapamycin Plus Bevacizumab in Advanced Cancers [Recruiting]

Kidney Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Rapamune (Sirolimus) in Kidney Transplant Recipients [Active, not recruiting]

An Open-Label, Comparative, Randomized, Prospective Study To Compare Sirolimus Versus Tacrolimus In De Novo Simultaneous Pancreas- Kidney Allograft Recipients Receiving An Induction Therapy With Antithymocyte Globulin Plus Mycophenolate Mofetil Plus Corticosteroids [Recruiting]

Study Evaluating Rapamune® Maintenance Regimen [Recruiting]

Rapamycin in With High-Dose Etoposide and Cytarabine in Relapsed/Refractory Aggressive Lymphoid Malignancies [Recruiting]

Raptiva and Sirolimus in Islet Transplantation for Type 1 Diabetes [Recruiting]

Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization [Completed]

Comparison of Sirolimus Alone With Sirolimus Plus Tacrolimus in Type 1 Diabetic Recipients of Cultured Islet Cell Grafts [Terminated]

Sirolimus in Treating Patients With Advanced Pancreatic Cancer [Recruiting]

Sirolimus in Preventing Graft-Versus-Host Disease in Patients With Hematologic Malignancies Who Are Undergoing Allogeneic Hematopoietic Stem Cell Transplantation [Recruiting]

Pilot Trial of Treatment of Poor-Prognosis Iga Nephropathy With Low Exposure to Sirolimus. [Recruiting]

Study Investigating Rapamune for Post-Marketing Surveillance [Not yet recruiting]

The Effect of Sirolimus on the Pharmacokinetics of Tacrolimus [Recruiting]

Phase 1 Study With Sorafenib and Sirolimus [Recruiting]

Study Evaluating the Use of Sirolimus In Recipients Of Kidney Allografts From Expanded Criteria Donors (Ecd) [Recruiting]

Proleukin and Rapamune in Type 1 Diabetes [Recruiting]

Sirolimus and Thymoglobulin to Prevent Kidney Transplant Rejection [Active, not recruiting]

Sirolimus as Treatment of Steroid-Refractory or Steroid-Dependent Chronic Graft-Versus-Host Disease [Recruiting]

Sirolimus and Mycophenolate Mofetil (MMF) as Graft Versus Host Disease (GVHD) Prophylaxis After Reduced Intensity Conditioning (RIC) Transplantation [Recruiting]

Gefitinib and Sirolimus in Treating Patients With Recurrent or Refractory Stage IIIB or Stage IV Non-Small Cell Lung Cancer [Recruiting]

Sirolimus and Cyclosporine for Treatment-Resistant Aplastic Anemia [Recruiting]

Sirolimus Therapy for Idiopathic and Lupus Membranous Nephropathy [Active, not recruiting]

Sirolimus Treatment in Patients With Autosomal Dominant Polycystic Kidney Disease: Renal Efficacy and Safety [Recruiting]

Liver Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Sirolimus in Recipients of a Liver Transplant [Active, not recruiting]

Erlotinib and Sirolimus in Treating Patients With Recurrent Malignant Glioma [Recruiting]

Study Evaluating Two Different Sirolimus-Based Immunosuppressive Regimens in Elderly Kidney Transplant Recipients [Completed]

Calcineurin Inhibitor Avoidance With Thymoglobulin and Sirolimus in Kidney Transplantation [Completed]

Immunosuppression in Patients Undergoing Liver Transplantation for Hepatocellular Carcinoma [Recruiting]

Efficacy and Safety of Sirolimus for Treating Lymphangioleiomyomatosis (LAM) [Recruiting]

Rapamycin vs Mycophenolate Mofetil in Kidney-Pancreas Recipients [Recruiting]

Pilot Study of the Evaluation of Subconjunctival Sirolimus in the Treatment of Bilateral Geographic Atrophy Associated With Age-Related Macular Degeneration [Recruiting]

Use of Sirolimus vs. Tacrolimus For African-American Renal Transplant Recipients [No longer recruiting]

Sirolimus-Eluting vs Zotarolimus-Eluting Stents for Chronic Total Coronary Occlusions [Recruiting]

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