Media Articles Related to Qutenza (Capsaicin)
Results from head to head study comparing Qutenza with pregabalin in PNP published
Source: Pain / Anesthetics News From Medical News Today [2015.11.20]
Astellas Pharma Europe Ltd. has announced the publication in the European Journal of Pain of a head to head, non-inferiority study that compared the capsaicin 8% patch (QUTENZATM) with pregabalin...
Cardiac Sonographers Extra Prone to Back, Neck, Wrist Pain
Source: Medscape Radiology Headlines [2015.11.27]
Staff in the echo lab were even more likely to have work-related musculoskeletal pain than technicians in the cath lab, in a new study.
Heartwire from Medscape
Reducing pain intensity may be the wrong treatment goal
Source: Pain / Anesthetics News From Medical News Today [2015.11.26]
Chronic Pain Treatment should focus on improving function and quality of life.It would seem intuitive that reducing pain intensity should be the primary goal of treatment for chronic pain.
Mindfulness Meditation 'Better Than Placebo' for Pain Relief
Source: Medscape NeurologyHeadlines [2015.11.25]
Pain relief through mindfulness meditation not only is significantly greater than that achieved by placebo but also utilizes different neural mechanisms, say US researchers.
Medscape Medical News
New pain mechanisms revealed for neurotoxin in spinal cord injury
Source: Neurology / Neuroscience News From Medical News Today [2015.11.25]
A toxin released by the body in response to spinal cord injuries increases pain by causing a proliferation of channels containing pain sensors, new research shows, and this hypersensitivity also...
Published Studies Related to Qutenza (Capsaicin)
Capsaicin 8% patch for treprostinil subcutaneous infusion site pain in pulmonary
hypertension patients. 
trepostinil-induced pain... CONCLUSIONS: Further investigation of the efficacy of capsaicin 8% patch in this
Inhibition of capsaicin-driven nasal hyper-reactivity by SB-705498, a TRPV1
pharmacodynamics (PD) of intranasal SB-705498, a selective TRPV1 antagonist... CONCLUSIONS: Intranasal SB-705498 has an appropriate safety and PK profile for
Diclofenac with or without an antiemetic for acute migraine headaches in adults. 
CONCLUSIONS: Oral diclofenac potassium 50 mg is an effective treatment
Topical capsaicin (low concentration) for chronic neuropathic pain in adults. 
CONCLUSIONS: There were insufficient data to draw any conclusions about
Capsaicin instillation for postoperative pain following total knee arthroplasty: a preliminary report of a randomized, double-blind, parallel-group, placebo-controlled, multicentre trial. [2011.12.01]
BACKGROUND: Pain following total knee arthroplasty (TKA) interferes with rehabilitation. Capsaicin applied in high concentration to nociceptors can cause relatively selective C-fibre desensitization for a period of weeks to months. Resultant long-lasting analgesia might facilitate rehabilitation. OBJECTIVE: The objective of this study was to determine if direct instillation of a high-concentration capsaicin preparation into the wound following TKA would provide pain relief, improve physical functioning and rehabilitation, and reduce opioid requirements... CONCLUSION: Despite having higher BMIs, patients in the capsaicin group achieved comparable or better pain scores with significantly less opioid use in the first 3 postoperative days. They also had less pruritus, which may have been a consequence of the opioid-sparing effect. The effects of capsaicin with respect to function, however, appeared to be longer lasting, with improved active ROM reported at 14 days.
Clinical Trials Related to Qutenza (Capsaicin)
The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site Pain [Recruiting]
Subcutaneous treprostinil (Remodulin) is effective therapy for pulmonary arterial
hypertension, a life threatening disease of the lung blood vessels. Unfortunately,
treprostinil is irritating to the skin and many patients experience intense pain at the
infusion site for the first 7-10 days after placing a new subcutaneous infusion site.
Qutenza is an FDA approved formulation of 8% capsaicin that is approved for the treatment of
post-herpetic neuralgia, a painful skin condition. The investigators hypothesize that
pretreatment of an area of skin with Qutenza would decrease the pain associated with a new
treprostinil infusion site. The investigators hope that Qutenza will decrease both the
intensity of the pain and the duration of the pain after patients place a new treprostinil
In this initial study, the investigators will provide Qutenza in open-label, unblinded
fashion and ask patients to rate their pain using a diary tool with which they are already
The Effect of Capsaicin and Cinnamaldehyde on Intestinal Permeability [Completed]
An altered permeability has been proposed to play an important role in the pathogenesis of
several gastrointestinal disorders, such as irritable bowel syndrome and inflammatory bowel
disease. Nutrients derived from food are able to influence the permeability of the intestine
and can therefore also affect gastrointestinal symptoms. In this study, the investigators
will investigate the effects of capsaicine and cinnamaldehyde, which can be found in hot
peppers and cinnamon, respectively, on gastrointestinal physiology.
To obtain more information about the effects of capsaicin and cinnamaldehyde on the
intestine, these substances will be infused directly in the duodenum. Hereafter, the
permeability of the intestine, gallbladder motility and the effects on satiety will be
Duodenal capsaicin and cinnamaldehyde infusion induces changes in the intestinal epithelial
barrier function by selectively acting on TRPV1 and TRPA1 receptors and releasing serotonin
from enterochromaffin cells as determined by the multi sugar permeability test
Capsaicin 8% Patch for Spinal Cord Injury Neuropathic Pain [Not yet recruiting]
A prospective study to determine the effectiveness and longevity of 8% capsaicin patch in
treating neuropathic pain in persons with spinal cord injury. The investigators will study
spinal cord injury patients at South Texas Veterans Health Care Systems Spinal Cord Injury
inpatient unit and outpatient clinics.
Intranasal Capsaicin Treatment for Non-Allergic Irritant Rhinitis [Recruiting]
The proposed study seeks to investigate the effect of intranasal capsaicin treatment in
patient with Non-allergic irritant rhinitis (NAIR), as well as evaluate optical rhinometry
(ORM) as a means to quantify symptomatic improvement in NAIR patients during and after
Efficacy of Topical Capsaicin on Chronic Neck Pain [Not yet recruiting]
The purpose of this study is to determine whether topical capsaicin patch can effectively
reduce chronic neck pain.
Reports of Suspected Qutenza (Capsaicin) Side Effects
Application Site Pain (26),
Application Site Erythema (15),
Condition Aggravated (8),
Application Site Swelling (5),
Application Site Pruritus (5),
Application Site Vesicles (5), more >>