Media Articles Related to Qutenza (Capsaicin)
Hormones Might Offer Relief From Chronic Pain, Small Study Suggests
Source: Yahoo Health News [2014.03.08]
SATURDAY, March 8, 2014 (HealthDay News) -- A combination of two hormones might make a difference in reducing suffering in people with chronic pain, according to a small, preliminary study. Seven of 9 patients reported a 30 percent to 40 percent d...
Extra Weight Adds $$ to Chest Pain Treatment
Source: MedPage Today Cardiovascular [2014.03.06]
(MedPage Today) -- Among patients showing up in the emergency department with chest pain and dyspnea, those carrying extra weight tended to incur higher costs and have longer hospital stays, researchers found.
New research points to talking-therapy treatments to manage osteoarthritis pain
Source: Arthritis / Rheumatology News From Medical News Today [2014.03.05]
Scientists have shown for the first time that the abnormalities in the way the brain experiences pain may be to blame for the chronic pain suffered by osteoarthritis patients.
New approach to breast reconstruction surgery reduces opioid painkiller use, hospital stays
Source: Breast Cancer News From Medical News Today [2014.03.05]
A new approach to breast reconstruction surgery aimed at helping patients' bodies get back to normal more quickly cut their postoperative opioid painkiller use in half and meant a day less in the hospital on average, a Mayo Clinic study found.
Researchers find link between chronic pain and heart disease
Source: Cardiovascular / Cardiology News From Medical News Today [2014.03.05]
Elderly people who have chronic muscle pain are at a significantly increased risk of having heart disease - researchers at Teesside University have found.Almost half of elderly people who have suffered chronic musculoskeletal pain (CMP) go on to suffer cardiovascular disease (CVD), researchers suggest.
Published Studies Related to Qutenza (Capsaicin)
Topical capsaicin (low concentration) for chronic neuropathic pain in adults. 
CONCLUSIONS: There were insufficient data to draw any conclusions about
Capsaicin instillation for postoperative pain following total knee arthroplasty: a preliminary report of a randomized, double-blind, parallel-group, placebo-controlled, multicentre trial. [2011.12.01]
BACKGROUND: Pain following total knee arthroplasty (TKA) interferes with rehabilitation. Capsaicin applied in high concentration to nociceptors can cause relatively selective C-fibre desensitization for a period of weeks to months. Resultant long-lasting analgesia might facilitate rehabilitation. OBJECTIVE: The objective of this study was to determine if direct instillation of a high-concentration capsaicin preparation into the wound following TKA would provide pain relief, improve physical functioning and rehabilitation, and reduce opioid requirements... CONCLUSION: Despite having higher BMIs, patients in the capsaicin group achieved comparable or better pain scores with significantly less opioid use in the first 3 postoperative days. They also had less pruritus, which may have been a consequence of the opioid-sparing effect. The effects of capsaicin with respect to function, however, appeared to be longer lasting, with improved active ROM reported at 14 days.
A randomized, double-blind, parallel trial comparing capsaicin nasal spray with placebo in subjects with a significant component of nonallergic rhinitis. [2011.08]
OBJECTIVE: To investigate the efficacy and safety of ICX72 or Sinus Buster, a proprietary homeopathic preparation of Capsicum annum and Eucalyptol, versus placebo administered continuously over 2 weeks in subjects with a significant component of nonallergic rhinitis (NAR)... CONCLUSION: This is the first controlled trial demonstrating intranasal capsaicin, when used continuously over 2 weeks, rapidly and safely improves symptoms in rhinitis subjects with a significant NAR component. Copyright (c) 2011 American College of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.
Self-reported sleep duration associated with distraction analgesia, hyperemia, and secondary hyperalgesia in the heat-capsaicin nociceptive model. [2011.07]
Although sleep deprivation is known to heighten pain sensitivity, the mechanisms by which sleep modifies nociception are largely unknown. Few studies of sleep-pain interactions have utilized quantitative sensory testing models that implicate specific underlying physiologic mechanisms...
Effects of lidocaine patch on intradermal capsaicin-induced pain: a double-blind, controlled trial. [2011.03]
This study evaluated the effects of topical lidocaine on skin sensation and on intradermal capsaicin-induced pain and hyperalgesia. A randomized, double-blinded, placebo controlled methodology was used...
Clinical Trials Related to Qutenza (Capsaicin)
The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site Pain [Recruiting]
Subcutaneous treprostinil (Remodulin) is effective therapy for pulmonary arterial
hypertension, a life threatening disease of the lung blood vessels. Unfortunately,
treprostinil is irritating to the skin and many patients experience intense pain at the
infusion site for the first 7-10 days after placing a new subcutaneous infusion site.
Qutenza is an FDA approved formulation of 8% capsaicin that is approved for the treatment of
post-herpetic neuralgia, a painful skin condition. The investigators hypothesize that
pretreatment of an area of skin with Qutenza would decrease the pain associated with a new
treprostinil infusion site. The investigators hope that Qutenza will decrease both the
intensity of the pain and the duration of the pain after patients place a new treprostinil
In this initial study, the investigators will provide Qutenza in open-label, unblinded
fashion and ask patients to rate their pain using a diary tool with which they are already
Method of Pre-treatment for Application of QUTENZA Capsaicin 8% Patch [Recruiting]
The Summary of product characteristics (SmPC) for QUTENZA advises that topical anaesthetic
is applied prior to the application of QUTENZA. This is a multi-center, randomized,
assessor-blinded study which will investigate the use of an oral analgesic as an alternative
form of pre-treatment for QUTENZA.
Acute Response Capsaicin Flare Study [Recruiting]
Prior to administering PF-04427429 to patients we wish to increase the understanding of
functional effects associated with calcitonin gene related peptide (CGRP) pathways. This
study will examine whether it is possible for a single dose of PF-04427429 to acutely
attenuate a capsaicin induced flare response.
Safety and Effectiveness of Repeated Administration of QUTENZA Patches for Treatment of Pain Caused by Nerve Damage [Recruiting]
In this study all patients will be treated with the same medicine, the QUTENZA patch.
Subjects will receive up to 6 QUTENZA patch applications over 12 months.
Qutenza«-Remodulin« in Pulmonary Arterial Hypertension Patients [Recruiting]
The investigators hypothesise that pre-application of Qutenza« patches to the skin may
reduce pain at the site of Remodulin« SC infusion (sited 1 to 2 weeks later at the site of
Qutenza pre-application), in which case it would greatly improve the quality of life of the
patients, and enable many more to continue with this treatment. It may also provide new
information to support the use of Qutenza« patches for preventing and reducing pain produced
The present study will explore the efficacy of single applications of Qutenza┬« (capsaicin 8%
patch) in reducing site pain caused by continuous SC infusion of Remodulin┬«, in pulmonary
arterial hypertension patients, as assessed by changes in subjective pain rating score
and/or pain and sensory testing.
Reports of Suspected Qutenza (Capsaicin) Side Effects
Application Site Pain (26),
Application Site Erythema (15),
Condition Aggravated (8),
Application Site Swelling (5),
Application Site Pruritus (5),
Application Site Vesicles (5), more >>