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Quinaretic (Quinapril Hydrochloride / Hydrochlorothiazide) - Summary

 
 



BOXED WARNING

USE IN PREGNANCY

When used in pregnancy during the second and third trimesters, ACE inhibitors can cause injury and even death to the developing fetus. When pregnancy is detected, QUINARETIC should be discontinued as soon as possible. See WARNINGS: Fetal/Neonatal Morbidity and Mortality.

 

QUINARETIC SUMMARY

QUINARETIC is a fixed-combination tablet that combines an angiotensin-converting enzyme (ACE) inhibitor, quinapril hydrochloride, and a thiazide diuretic, hydrochlorothiazide.

QUINARETIC is indicated for the treatment of hypertension. This fixed combination is not indicated for the initial therapy of hypertension (see DOSAGE AND ADMINISTRATION).

In using QUINARETIC, consideration should be given to the fact that another angiotensin-converting enzyme inhibitor, captopril, has caused agranulocytosis, particularly in patients with renal impairment or collagen-vascular disease. Available data are insufficient to show that quinapril does not have a similar risk (see WARNINGS: Neutropenia/Agranulocytosis).

Angioedema in Black Patients:

Black patients receiving ACE inhibitor monotherapy have been reported to have a higher incidence of angioedema compared to non-blacks. It should also be noted that in controlled clinical trials, ACE inhibitors have an effect on blood pressure that is less in black patients than in non-blacks.


See all Quinaretic indications & dosage >>

NEWS HIGHLIGHTS

Media Articles Related to Quinaretic (Quinapril / Hydrochlorothiazide)

Yoga Improves Quality of Life in Pulmonary Hypertension
Source: Medscape Critical Care Headlines [2016.04.29]
Adults with pulmonary arterial hypertension could derive some relief from yoga, results from a preliminary study suggest. The 12-week program eased anxiety and depression, among other measures.
Medscape Medical News

RA: Hypertension, High LDL Often Missed or Undertreated
Source: Medscape Rheumatology Headlines [2016.04.25]
Patients with rheumatoid arthritis are likely to need more intensive monitoring and treatment of cardiovascular risk factors, but often receive less.
Medscape Medical News

Healthy diet could lower hypertension risk for women with gestational diabetes
Source: Diabetes News From Medical News Today [2016.04.19]
Researchers have found that the long-term risk of high blood pressure that is caused by pregnancy-related diabetes could be reduced by following a healthy diet.

Pulmonary Hypertension
Source: MedicineNet Fainting Specialty [2016.03.30]
Title: Pulmonary Hypertension
Category: Diseases and Conditions
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 3/30/2016 12:00:00 AM

High Blood Pressure (Hypertension) Quiz: Test Your Medical IQ
Source: MedicineNet Nosebleed Specialty [2016.01.05]
Title: High Blood Pressure (Hypertension) Quiz: Test Your Medical IQ
Category: MedicineNet Quiz
Created: 2/9/2011 12:56:00 PM
Last Editorial Review: 1/5/2016 2:12:26 PM

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Page last updated: 2016-04-29

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