Quinapril (Quinapril Hydrochloride) - Description

Rx only

DESCRIPTION

Quinapril hydrochloride, USP is the hydrochloride salt of quinapril, the ethyl ester of a non-sulfhydryl, angiotensin-converting enzyme (ACE) inhibitor, quinaprilat.

Quinapril hydrochloride, USP is chemically described as [3S-[2[R*(R*)],3R*]]-2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid, monohydrochloride. Its empirical formula is C₂₅H₃₀N₂O₅•HCI and its structural formula is:

Quinapril hydrochloride, USP is a white to off-white amorphous powder that is freely soluble in aqueous solvents.

Quinapril hydrochloride tablets, USP contain 5 mg, 10 mg, 20 mg, or 40 mg of quinapril for oral administration. Each tablet also contains black iron oxide, candelilla wax powder, crospovidone, dibasic calcium phosphate, hypromellose 2910 3cP, hypromellose 2910 6cP, magnesium carbonate powder heavy, magnesium stearate, polyethylene glycol 400, polysorbate 80, povidone, red iron oxide, titanium dioxide and yellow iron oxide.