Very few instances of contact allergic reactions to anthralin have been reported. However, transient primary irritation of the normal skin or uninvolved skin surrounding the treated lesions is more frequently seen. If the initial treatment produces excessive soreness or if the lesions spread, reduce frequency of application and, in extreme cases, discontinue use and consult a physician.
Psoriatec cream may stain skin, hair or fabrics. Some temporary discoloration of hair and fingernails may arise during the period of treatment but should be minimized by careful application. Staining of fabrics may be permanent, so contact should be avoided.