Media Articles Related to Psoriatec (Anthralin)
Study underway to develop personalised treatments for psoriasis
Source: Health News from Medical News Today [2013.11.29]
Queen Mary University of London is working to create a new test which helps pinpoint the most effective treatment to tackle the skin condition psoriasis - as part of a world-leading partnership between King's College London, the University of Manchester, Liverpool University and Newcastle University.The partnership will develop a targeted approach to psoriasis treatment - an approach also known as stratified medicine - with the aim of eventually using the test to help the 1 million NHS patients who suffer from the painful skin condition.
Study Finds Links Between Psoriasis, Heart Failure
Source: MedicineNet Psoriasis Specialty [2013.11.04]
Title: Study Finds Links Between Psoriasis, Heart Failure
Category: Health News
Created: 11/1/2013 4:36:00 PM
Last Editorial Review: 11/4/2013 12:00:00 AM
Psoriasis Foundation vaccine recommendations for people on immunosuppressive drugs
Source: Arthritis / Rheumatology News From Medical News Today [2013.10.22]
People with psoriasis and psoriatic arthritis should talk with their doctors about vaccinations before starting on biologic drugs or other treatments that suppress the immune system, according to recommendations from the National Psoriasis Foundation (NPF) Medical Board. Additionally, people should only take inactivated vaccines while on immunosuppressive drugs, the report notes.
Psoriasis, Kidney Disease Link Found (CME/CE)
Source: MedPage Today Dermatology [2013.10.16]
(MedPage Today) -- For the first time, researchers say they've found an association between moderate and severe psoriasis and chronic kidney disease.
Study Sees Link Between Psoriasis, Kidney Problems
Source: MedicineNet Itch Specialty [2013.10.16]
Title: Study Sees Link Between Psoriasis, Kidney Problems
Category: Health News
Created: 10/15/2013 7:36:00 PM
Last Editorial Review: 10/16/2013 12:00:00 AM
Published Studies Related to Psoriatec (Anthralin)
Comparison of azelaic acid and anthralin for the therapy of patchy alopecia areata: a pilot study. 
CONCLUSION: The present pilot study showed that the use of azelaic acid gave similar results to anthralin with regard to hair regrowth, and that it can be an effective topical therapy for patchy AA. More extensive trials are necessary, however, to reach a definitive conclusion.
Effect of H1-receptor blockade on anthralin inflammation. 
The effect of terfenadine, an H1-receptor antagonist, on anthralin inflammation was studied in 12 subjects. Subjects were randomised to receive terfenadine 60 mg or placebo b.d... This study shows that H1-receptor blockade does not inhibit anthralin inflammation.
Anthralin-corticosteroid combination therapy in the treatment of chronic plaque psoriasis. [1988.04]
A prospective randomized trial of anthralin in Lassar's paste compared with anthralin in 0.0125% clobetasol propionate in the treatment of chronic plaque psoriasis was undertaken. The psoriatic skin of patients treated with the corticosteroid-anthralin combination cleared significantly more quickly than those treated with anthralin alone, with a mean time to clearance of 14.9 days compared with 18.5 days, and with lower concentrations of anthralin...
An EPR method for estimating activity of antioxidants in mouse skin using an anthralin-derived radical model. [2010.03]
Inhibitory effects of intravenously or orally administered antioxidants on the anthralin-derived radical generated in skin (mainly in the epidermis) of living mice by ultraviolet-A (UVA) irradiation were estimated. Anthralin was applied to the dorsal skin of living mice and the mice were then exposed to UVA.
Fluorescence remission spectroscopy of psoriatic lesions and the effect of topical anthralin therapy. [2009.12]
BACKGROUND: Psoriatic lesions are characterized by induration, scaling and erythema. Erythema is a result of inflammation and increased microvascular blood flow. Anthralin is the strongest topical antipsoriatic drug that causes clearing of psoriatic lesions and temporary remission. OBJECTIVE: The objective evaluation of skin perfusion might be a suitable way to gain a better insight in the pathophysiological process of this disease and to evaluate the response to antipsoriatic anthralin therapy... CONCLUSIONS: Vascular perfusion is increased in psoriatic lesions as demonstrated by remission spectroscopy. NADH-fluorescence is reduced in lesional psoriatic skin and in anthralin-induced erythema. FRIS is a suitable tool for objective evaluation of the cutaneous response to antipsoriatic treatment.
Clinical Trials Related to Psoriatec (Anthralin)
Steroids Added to Dithranol and Narrow Band UVB (UVBnb) in Psoriasis [Recruiting]
(i) To assess the effect of adjunctive topical steroids in the combined treatment with UVBnb
and dithranol on the remission time after therapy till a relapse of psoriasis defined as 50%
loss of PASI improvement obtained through the antecedent treatment.
(ii) To assess the impact of adjuvant topical steroids in the combined treatment with UVBnb
and dithranol on the clearing time of psoriasis lesions under therapy (PASI 75).
- Trial with medicinal product
Effect of Adalimumab on Vascular Inflammation in Patients With Moderate to Severe Plaque Psoriasis [Recruiting]
This study is to determine the effect of adalimumab on inflammation of blood vessels that
could lead to heart attack in patients with psoriasis. Changes to the carotid artery and
ascending aorta will be evaluated in patients treated with adalimumab (systemic treatment)
and compared against patients treated with a topical treatment that does not affect the