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Propranolol (Propranolol Hydrochloride) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The following adverse events were observed and have been reported in patients using propranolol.

Cardiovascular:

Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.

Central Nervous System:

Light-headedness; mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate release formulations, fatigue, lethargy, and vivid dreams appear dose related.

Gastrointestinal:

Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.

Allergic:

Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions; pharyngitis and agranulocytosis; erythematous rash; fever combined with aching and sore throat; laryngospasm; respiratory distress.

Respiratory:

Bronchospasm.

Hematologic:

Agranulocytosis, nonthrombocytopenic purpura, and thrombocytopenic purpura.

Autoimmune:

Systemic lupus erythematosus (SLE).

Skin and mucous membranes:

Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes, and conjunctivae reported for a beta-blocker (practolol) have not been associated with propranolol.

Genitourinary:

Male impotence; Peyronie's disease.



REPORTS OF SUSPECTED PROPRANOLOL SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Propranolol. The information is not vetted and should not be considered as verified clinical evidence.

Possible Propranolol side effects / adverse reactions in 37 year old female

Reported by a physician from United States on 2011-10-03

Patient: 37 year old female

Reactions: Cardiogenic Shock

Adverse event resulted in: hospitalization

Suspect drug(s):
Citalopram Hydrobromide
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Propranolol
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Bupropion HCL
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Propranolol side effects / adverse reactions in 76 year old male

Reported by a health professional (non-physician/pharmacist) from Belgium on 2011-10-04

Patient: 76 year old male

Reactions: Dyspnoea, Poisoning, Hypotension, Bradycardia, Somnolence

Adverse event resulted in: hospitalization

Suspect drug(s):
Propranolol
    Dosage: 80 mg, qhs
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Diltiazem Hydrochloride
    Dosage: 300 mg, qam
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Bisoprolol (Unknown)
    Dosage: 2.5 mg, qam
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



Possible Propranolol side effects / adverse reactions in 37 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-04

Patient: 37 year old female

Reactions: Overdose, Cardiogenic Shock, Hypokalaemia

Adverse event resulted in: hospitalization

Suspect drug(s):
Citalopram Hydrobromide
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Propranolol
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Insulin (Insulin)
    Indication: Cardiogenic Shock

Bupropion HCL
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication



See index of all Propranolol side effect reports >>

Drug label data at the top of this Page last updated: 2013-01-17

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