Propranolol (Propranolol Hydrochloride) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The following adverse events were observed and have been reported in patients using propranolol.

Cardiovascular: Bradycardia; congestive heart failure; intensification of AV block; hypotension; paresthesia of hands; thrombocytopenic purpura; arterial insufficiency, usually of the Raynaud type.

Central Nervous System: Light-headedness, mental depression manifested by insomnia, lassitude, weakness, fatigue; catatonia; visual disturbances; hallucinations; vivid dreams; an acute reversible syndrome characterized by disorientation for time and place, short-term memory loss, emotional lability, slightly clouded sensorium, and decreased performance on neuropsychometrics. For immediate-release formulations, fatigue, lethargy, and vivid dreams appear dose related.

Gastrointestinal: Nausea, vomiting, epigastric distress, abdominal cramping, diarrhea, constipation, mesenteric arterial thrombosis, ischemic colitis.

Allergic: Hypersensitivity reactions, including anaphylactic/anaphylactoid reactions, pharyngitis and agranulocytosis; erythematous rash, fever combined with aching and sore throat; laryngospasm, and respiratory distress.

Respiratory: Bronchospasm.

Hematologic: Agranulocytosis, nonthrombocytopenic purpura, thrombocytopenic purpura.

Autoimmune: Systemic lupus erythematosus.

Skin and Mucous Membranes: Stevens-Johnson Syndrome, toxic epidermal necrolysis, dry eyes, exfoliative dermatitis, erythema multiforme, urticaria, alopecia, SLE-like reactions, and psoriasiform rashes. Oculomucocutaneous syndrome involving the skin, serous membranes and conjunctivae reported for a beta blocker (practolol) have not been associated with propranolol.

Genitourinary: Male impotence; Peyronie's disease.

REPORTS OF SUSPECTED PROPRANOLOL SIDE EFFECTS / ADVERSE REACTIONS

Possible Propranolol side effects / adverse reactions in 37 year old female

Reported by a physician from United States on 2011-10-03

Patient: 37 year old female

Reactions: Cardiogenic Shock

Adverse event resulted in: hospitalization

Suspect drug(s):
Citalopram Hydrobromide
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Propranolol
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Bupropion HCL
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Possible Propranolol side effects / adverse reactions in 76 year old male

Reported by a health professional (non-physician/pharmacist) from Belgium on 2011-10-04

Patient: 76 year old male

Reactions: Dyspnoea, Poisoning, Hypotension, Bradycardia, Somnolence

Adverse event resulted in: hospitalization

Suspect drug(s):
Propranolol
    Dosage: 80 mg, qhs
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Diltiazem Hydrochloride
    Dosage: 300 mg, qam
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Bisoprolol (Unknown)
    Dosage: 2.5 mg, qam
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Possible Propranolol side effects / adverse reactions in 37 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-04

Patient: 37 year old female

Reactions: Overdose, Cardiogenic Shock, Hypokalaemia

Adverse event resulted in: hospitalization

Suspect drug(s):
Citalopram Hydrobromide
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Propranolol
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication

Insulin (Insulin)
    Indication: Cardiogenic Shock

Bupropion HCL
    Dosage: oral
    Administration route: Oral
    Indication: Product Used FOR Unknown Indication