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Propoxyphene Napsylate and Acetaminophen (Propoxyphene Napsylate / Acetaminophen) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

In a survey conducted in hospitalized patients, less than 1% of patients taking propoxyphene hydrochloride at recommended doses experienced side effects. The most frequently reported were dizziness, sedation, nausea, and vomiting. Some of these adverse reactions may be alleviated if the patient lies down.

Other adverse reactions include constipation, abdominal pain, skin rashes, lightheadedness, headache, weakness, euphoria, dysphoria, hallucinations, and minor visual disturbances.

Liver dysfunction has been reported in association with both active components of propoxyphene napsylate and acetaminophen tablets. Propoxyphene therapy has been associated with abnormal liver function tests and, more rarely, with instances of reversible jaundice (including cholestatic jaundice). Hepatic necrosis may result from acute overdose of acetaminophen (see OVERDOSAGE). In chronic ethanol abusers, this has been reported rarely with short-term use of acetaminophen dosages of 2.5 to 10 g/day. Fatalities have occurred.

Renal papillary necrosis may result from chronic acetaminophen use, particularly when the dosage is greater than recommended and when combined with aspirin.

Subacute painful myopathy has occurred following chronic propoxyphene overdosage.



REPORTS OF SUSPECTED PROPOXYPHENE NAPSYLATE AND ACETAMINOPHEN SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Propoxyphene Napsylate and Acetaminophen. The information is not vetted and should not be considered as verified clinical evidence.

Possible Propoxyphene Napsylate and Acetaminophen side effects / adverse reactions in 73 year old female

Reported by a physician from United States on 2012-02-01

Patient: 73 year old female

Reactions: Palpitations, Dizziness, Blood Pressure Diastolic Increased

Adverse event resulted in: hospitalization

Suspect drug(s):
Propoxyphene Napsylate and Acetaminophen
    Indication: Pain
    Start date: 2009-08-01
    End date: 2010-11-01

Propoxyphene Napsylate and Acetaminophen
    Indication: Hypertension
    Start date: 2009-08-01
    End date: 2010-11-01

Other drugs received by patient: Hydralazine HCL



Possible Propoxyphene Napsylate and Acetaminophen side effects / adverse reactions in 79 year old female

Reported by a physician from United States on 2012-02-01

Patient: 79 year old female

Reactions: Palpitations

Suspect drug(s):
Propoxyphene Napsylate and Acetaminophen

Other drugs received by patient: Atenolol; Verapamil; Acetylsalicylic Acid SRT; Clonazepam



Possible Propoxyphene Napsylate and Acetaminophen side effects / adverse reactions in 24 year old male

Reported by a physician from United States on 2012-02-01

Patient: 24 year old male

Reactions: Blood Pressure Increased, Anxiety, Palpitations, Nausea, Disorientation, Hyperhidrosis

Suspect drug(s):
Propoxyphene Napsylate and Acetaminophen



See index of all Propoxyphene Napsylate and Acetaminophen side effect reports >>

Drug label data at the top of this Page last updated: 2011-06-20

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