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Proloprim (Trimethoprim) - Indications and Dosage


Indications and Usage:

For the treatment of initial episodes of uncomplicated urinary tract infections due to susceptible strains of the following organisms: Escherichia coli, Proteus mirabilis, Klebsiella pneumoniae, Enterobacter species, and coagulase-negative Staphylococcus species, including S. saprophyticus.

Cultures and susceptibility tests should be performed to determine the susceptibility of the bacteria to trimethoprim. Therapy may be initiated prior to obtaining the results of these tests.

Dosage and Administration:

The usual oral adult dosage is 100 mg of PROLOPRIM every 12 hours or 200 mg PROLOPRIM every 24 hours, each for 10 days. The use of trimethoprim in patients with a creatinine clearance of less than 15 mL/min is not recommended. For patients with a creatinine clearance of 15 to 30 mL/min, the dose should be 50 mg every 12 hours.

How Supplied:

100-mg Tablets (white, scored, round-shaped), containing 100 mg trimethoprim–bottle of 100 (NDC 61570-057-01). Imprint on tablets “PROLOPRIM 09A.” Store at 15° to 25°C (59° to 77°F) in a dry place.

200-mg Tablets (yellow, scored, round-shaped), containing 200 mg trimethoprim–bottle of 100 (NDC 61570-058-01). Imprint on tablets “PROLOPRIM 200.” Store at 15° to 25°C (59° to 77°F) in a dry place and protect from light.

Rx Only.

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