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Prolixin (Fluphenazine Decanoate) - Summary

 

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PROLIXIN SUMMARY

PROLIXIN® ORAL CONCENTRATE
Fluphenazine Hydrochloride Oral Solution USP

Prolixin Decanoate is the decanoate ester of a trifluoromethyl phenothiazine derivative. It is a highly potent behavior modifier with a markedly extended duration of effect. Prolixin Decanoate is available for intramuscular or subcutaneous administration, providing 25 mg fluphenazine decanoate per mL in a sesame oil vehicle with 1.2% (w/v) benzyl alcohol as a preservative. At the time of manufacture, the air in the vials is replaced by nitrogen.

PROLIXIN (fluphenazine) is indicated for the following:

Prolixin Decanoate (Fluphenazine Decanoate Injection) is a long-acting parenteral antipsychotic drug intended for use in the management of patients requiring prolonged parenteral neuroleptic therapy (e.g., chronic schizophrenics).

Prolixin Decanoate has not been shown effective in the management of behavioral complications in patients with mental retardation.

PROLIXIN NEWS HIGHLIGHTS

Media Articles Related to Prolixin (Fluphenazine)

Putting The Brakes On Psychosis And Its Impact
Source: Schizophrenia News From Medical News Today [2008.08.14]

ICU Psychosis
Source: MedicineNet Biorhythms Specialty [2007.05.31]

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Published Studies Related to Prolixin (Fluphenazine)

The effects of olanzapine and fluphenazine on plasma cortisol, prolactin and muscle rigidity in schizophrenic patients: a double blind study. [2007.03.30]

A randomized double-blind 12-week study of quetiapine, risperidone or fluphenazine on sexual functioning in people with schizophrenia. [2006.04]

Risperidone, quetiapine, and fluphenazine in the treatment of patients with therapy-refractory schizophrenia. [2005.07]

Thyroid function in treatment-resistant schizophrenia patients treated with quetiapine, risperidone, or fluphenazine. [2005.01]

Treatment of schizophrenia with long-acting fluphenazine, haloperidol, or risperidone. [2007.11]

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Clinical Trials Related to Prolixin (Fluphenazine)

Fluphenazine Decanoate for Psoriasis [Terminated]

Fluphenazine in Treating Patients With Refractory Advanced Multiple Myeloma [Completed]

New Antipsychotic Strategies: Quetiapine and Risperidone vs. Fluphenazine in Treatment Resistant Schizophrenia [Active, not recruiting]

CATIE- Schizophrenia Trial [Completed]

more>>

Page last updated: 2008-08-14

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