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Prolastin (Alpha 1-Antitrypsin) - Published Studies


Prolastin Related Published Studies

Well-designed clinical trials related to Prolastin (Alpha 1-Antitrypsin)

The fibrinogen cleavage product Aalpha-Val360, a specific marker of neutrophil elastase activity in vivo. [2011.08]

Retinoid treatment of Emphysema in Patients on the Alpha-1 International Registry. The REPAIR study: study design, methodology and quality control of study assessments. [2010.12]

Pharmacokinetic comparability of Prolastin(R)-C to Prolastin(R) in alpha-antitrypsin deficiency: a randomized study. [2010.09.30]

Exploring the role of CT densitometry: a randomised study of augmentation therapy in alpha1-antitrypsin deficiency. [2009.06]

Prevalence of alpha-1 antitrypsin deficiency in poorly controlled asthma--results from the ALA-ACRC low-dose theophylline trial. [2007.10]

Alpha-1-antitrypsin replacement therapy: current status. [2006.03]

Multi-center study: the biochemical efficacy, safety and tolerability of a new alpha1-proteinase inhibitor, Zemaira. [2006.03]

Safety and efficacy of recombinant alpha(1)-antitrypsin therapy in cystic fibrosis. [2006.02]

Short-term variability of biomarkers of proteinase activity in patients with emphysema associated with type Z alpha-1-antitrypsin deficiency. [2005.05.31]

Emphysema in alpha1-antitrypsin deficiency: does replacement therapy affect outcome? [2005]

Prevalence of alpha1-antitrypsin phenotypes in patients with IgA nephropathy. [2004.12]

Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla. [2003.10]

Peripheral deposition of alpha1-protease inhibitor using commercial inhalation devices. [2003.08]

Biochemical efficacy and safety of a new pooled human plasma alpha(1)-antitrypsin, Respitin. [2002.07]

Alpha1-antitrypsin deficiency: a position statement of the Canadian Thoracic Society. [2001.03]

Alpha-1 proteinase inhibitor (a1PI) for preventing chronic lung disease in preterm infants. [2001]

Feasibility of a clinical trial of augmentation therapy for alpha(1)-antitrypsin deficiency. The Alpha 1-Antitrypsin Deficiency Registry Study Group. [2000.03]

A randomized clinical trial of alpha(1)-antitrypsin augmentation therapy. [1999.11]

Functional and antigenic concentrations of alpha-1-proteinase inhibitor after administration for the prevention of chronic lung disease of prematurity. [1999.09]

alpha1-Proteinase inhibitor therapy for the prevention of chronic lung disease of prematurity: a randomized, controlled trial. [1998.01]

Progress of emphysema in severe alpha 1-antitrypsin deficiency as assessed by annual CT. [1997.09]

Efficacy of systemically administered acetylsalicylic acid plus scaling on periodontal health and elastase-alpha 1-proteinase inhibitor in gingival crevicular fluid. [1996.03]

Effects of low dose methotrexate therapy on the concentration and the glycosylation of alpha 1-acid glycoprotein in the serum of patients with rheumatoid arthritis: a longitudinal study. [1994.12]

Well-designed clinical trials possibly related to Prolastin (Alpha 1-Antitrypsin)

Impact of non-linear smoking effects on the identification of gene-by-smoking interactions in COPD genetics studies. [2011.10]

Perioperative use of a neutrophil elastase inhibitor in video-assisted thoracoscopic oesophagectomy for cancer. [2011.07]

Short-term monotherapy in HIV-infected patients with a virus entry inhibitor against the gp41 fusion peptide. [2010.12.22]

Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation. [2010.04.05]

Pro- and prebiotic supplementation induces a transient reduction in hemoglobin concentration in infants. [2009.11]

Pro- and Prebiotic Supplementation Induces a Transient Reduction in Hemoglobin Concentration in Infants. [2009.07.28]

Alterations in the human lung proteome with lipopolysaccharide. [2009.05.11]

The benefit of daily photoprotection. [2008.05]

No effects of probiotics on atopic dermatitis in infancy: a randomized placebo-controlled trial. [2006.07]

Rectal bleeding in infancy: clinical, allergological, and microbiological examination. [2006.04]

Effects of ulinastatin on pulmonary artery pressure during abdominal aortic aneurysmectomy. [2006.02]

Probiotic effects on faecal inflammatory markers and on faecal IgA in food allergic atopic eczema/dermatitis syndrome infants. [2005.02]

Residues 34-39 in the thyrotropin receptor are not the target of autoantibodies from sera of patients with Graves' disease. [2004.08]

Tissue trauma after vaginal hysterectomy and colporrhaphy versus abdominal hysterectomy: a randomised controlled study. [2004.08]

Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug. [2004.03]

Effect of early enteral nutrition on intestinal permeability, intestinal protein loss, and outcome in dogs with severe parvoviral enteritis. [2003.11]

The value of routine antibiotic prophylaxis in mandibular third molar surgery: acute-phase protein levels as indicators of infection. [2001.06]

Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh. [2000.09]

A randomized cross-over study on the effects of levonorgestrel- and desogestrel-containing oral contraceptives on the anticoagulant pathways. [2000.07]

Treatment of iron deficiency anemia and associated protein-losing enteropathy in children. [2000.01]

Activation of the contact system of coagulation does not contribute to the hemostatic imbalance in hypertriglyceridemia. [1999.10]

Reducing neutrophil elastase-induced lung injury. [1999.03]

Inhaled budesonide in ventilator-dependent preterm infants: a randomized, double-blind pilot study. [1999]

Activation of the protein C system during cardiopulmonary bypass with and without aprotinin. [1998.12]

Peritoneal lavage with aprotinin in patients with severe acute pancreatitis. Effects on plasma and peritoneal levels of trypsin and leukocyte proteases and their major inhibitors. [1998.08]

Steroids in the hemolytic uremic syndrome. [1998.02]

Probiotics: a novel approach in the management of food allergy. [1997.02]

Ozone exposure has both a priming effect on allergen-induced responses and an intrinsic inflammatory action in the nasal airways of perennially allergic asthmatics. [1995.05]

Local serum application: restoration of sufficient host defense in human peritonitis. [1994.01]

Acute effects of a single dose of porcine surfactant on patients with the adult respiratory distress syndrome. [1994.01]

Effects of dexamethasone on chemotactic activity and inflammatory mediators in tracheobronchial aspirates of preterm infants at risk for chronic lung disease. [1993.06]

The effect of bed rest and intra-articular steroids on the acute phase response in rheumatoid arthritis. [1993.01]

The effect of epidural blockade on postoperative hypercoagulability following abdominal aortic bypass surgery. [1992.11]

The influence of tourniquet ischaemia on post-operative degranulation of polymorphonuclear granulocytes. [1992.05]

Attenuation of intra-operative surgical stress response has no influence on post-operative degranulation of polymorphonuclear granulocytes. [1991.09]

Effect of dexamethasone on pulmonary inflammation and pulmonary function of ventilator-dependent infants with bronchopulmonary dysplasia. [1991.05]

Comparison of the clinical performance, contraceptive efficacy and acceptability of levonorgestrel-releasing IUD and Norplant-2 implants in China. [1990.05]

Blood coagulation in postmenopausal women given estrogen treatment: comparison of transdermal and oral administration. [1988.02]

Multicentre clinical trial of low volume fresh frozen plasma therapy in acute pancreatitis. [1987.10]

Other research related to Prolastin (Alpha 1-Antitrypsin)

Relation of functional characteristics and serum alpha-1-antitrypsin (AAT) concentration in patients with PiMM phenotype and chronic obstructive pulmonary disease (COPD). [2011.12]

ANCA-associated vasculitis is linked to carriage of the Z allele of alpha antitrypsin and its polymers. [2011.10]

Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing alpha(1)-Antitrypsin: Interim Results. [2011.10]

A Review of Alpha-1 Antitrypsin Deficiency. [2011.09.29]

Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia-reperfusion injury. [2011.08]

Oxidation of Z alpha1-antitrypsin by cigarette smoke induces polymerization: a novel mechanism of early-onset emphysema. [2011.08]

The prevalence of alpha-1 antitrypsin deficiency in Ireland. [2011.07.13]

The role of proteases, endoplasmic reticulum stress and SERPINA1 heterozygosity in lung disease and alpha-1 anti-trypsin deficiency. [2011.06]

Efficacy of alpha1-antitrypsin augmentation therapy in conditions other than pulmonary emphysema. [2011.04.12]

[Clinical trial endpoints in alpha-1-antitrypsin deficiency: interdisciplinary aspects]. [2011.04]

Matrix metalloproteinase-9 predicts pulmonary status declines in alpha1-antitrypsin deficiency. [2011.03.23]

The role of augmentation therapy in alpha-1 antitrypsin deficiency. [2011.03]

Alpha-1 antitrypsin protein and gene therapies decrease autoimmunity and delay arthritis development in mouse model. [2011.02.24]

[Practical applications of recombinant alpha-1-antitrypsin in medicine]. [2010.12]

Emerging drugs for alpha-1-antitrypsin deficiency. [2010.12]

Lung deposition of inhaled alpha-1-proteinase inhibitor (alpha 1-PI) - problems and experience of alpha1-PI inhalation therapy in patients with hereditary alpha1-PI deficiency and cystic fibrosis. [2010.11.04]

Therapeutic efficacy of alpha-1 antitrypsin augmentation therapy on the loss of lung tissue: an integrated analysis of 2 randomised clinical trials using computed tomography densitometry. [2010.10.05]

Intravenous alpha-1 antitrypsin augmentation therapy: systematic review. [2010.09]

Outdoor air pollution is associated with rapid decline of lung function in alpha-1-antitrypsin deficiency. [2010.08]

An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis. [2010.07.09]

Intravenous alpha-1 antitrypsin augmentation therapy for treating patients with alpha-1 antitrypsin deficiency and lung disease. [2010.07.07]

Influence of alpha-1 antitrypsin heterozygosity on treatment efficacy of HCV combination therapy. [2010.07]

Culture of impure human islet fractions in the presence of alpha-1 antitrypsin prevents insulin cleavage and improves islet recovery. [2010.07]

Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model. [2010.06]

Laboratory testing of individuals with severe alpha1-antitrypsin deficiency in three European centres. [2010.05]

alpha 1-antitrypsin enhances insulin secretion and prevents cytokine-mediated apoptosis in pancreatic beta-cells. [2010.05]

Studies of gamma-glutamyl transferase in alpha-1 antitrypsin deficiency. [2010.04]

The I-neb Adaptive Aerosol Delivery System enhances delivery of alpha1-antitrypsin with controlled inhalation. [2010.04]

Alpha 1 Antitrypsin Deficiency in Children with Chronic Liver Disease in North India. [2010.03.15]

Alpha-1-antitrypsin deficiency and smoking as risk factors for mismatch repair deficient colorectal cancer: a study from the colon cancer family registry. [2010.02]

Combination of alpha-1 antitrypsin and doxycycline suppresses collagen-induced arthritis. [2010.01]

Alpha1-antitrypsin deficiency: forgotten etiology. [2010]

Influence of alpha-1 antitrypsin heterozygosity on treatment efficacy of HCV combination therapy. [2010]

[Update: Alpha-1-antitrypsin deficiency. Summary of a scientific symposium at the conference of the Swiss Pneumologic Society on April 16th, 2009] [2009.12]

Quantitative airway assessment on computed tomography in patients with alpha1-antitrypsin deficiency. [2009.12]

Alpha-1 antitrypsin (AAT) deficiency - what are the treatment options? [2009.11]

Alpha-1 antitrypsin (AAT) deficiency - what are the treatment options? [2009.10.15]

alpha1-Antitrypsin deficiency: best clinical practice. [2009.10]

Influence of alpha-1 antitrypsin heterozygosity on treatment efficacy of HCV combination therapy. [2009.09.29]

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