Prograf Related Published Studies
Well-designed clinical trials related to Prograf (Tacrolimus)
A comparative study in efficacy and safety of 0.1% tacrolimus and 0.05%
clobetasol propionate ointment in discoid lupus erythematosus by modified
cutaneous lupus erythematosus disease area and severity index. [2012]
Single-blind, randomized controlled trial evaluating the treatment of facial seborrheic dermatitis with hydrocortisone 1% ointment compared with tacrolimus 0.1% ointment in adults. [2011.11.17]
A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients. [2011.11]
Double-blind, placebo-controlled trial of oral tacrolimus (FK506) in the management of hospitalized patients with steroid-refractory ulcerative colitis. [2011.09.01]
Randomised, double-blind, placebo-controlled study of tacrolimus in myasthenia gravis. [2011.09]
Effect of intraportal infusion of tacrolimus on ischaemic reperfusion injury in orthotopic liver transplantation: a randomized controlled trial. [2011.09]
A double-blind, randomized, placebo-controlled trial of topical tacrolimus 0.1% vs. clobetasol propionate 0.05% in childhood vitiligo. [2011.09]
Effects of diltiazem on pharmacokinetics of tacrolimus in relation to CYP3A5 genotype status in renal recipients: from retrospective to prospective. [2011.08]
Relationship of tacrolimus exposure and mycophenolate mofetil dose with renal function after renal transplantation. [2011.07.15]
Efficacy of tacrolimus 0.1% ointment in cutaneous lupus erythematosus: a multicenter, randomized, double-blind, vehicle-controlled trial. [2011.07]
Randomized trial of mycophenolate mofetil versus enteric-coated mycophenolate sodium in primary renal transplantation with tacrolimus and steroid avoidance: four-year analysis. [2011.06.15]
Reduced-dose tacrolimus with mycophenolate mofetil vs. standard-dose tacrolimus in liver transplantation: a randomized study. [2011.05]
Efficacy and safety of tacrolimus therapy for lupus nephritis: a systematic review of clinical trials. [2011.05]
Effects of topical corticosteroid and tacrolimus on ceramides and irritancy to sodium lauryl sulphate in healthy skin. [2011.05]
Drug interactions between the immunosuppressant tacrolimus and the cholesterol absorption inhibitor ezetimibe in healthy volunteers. [2011.04]
Effects of tacrolimus ointment on Toll-like receptors in atopic dermatitis. [2011.04]
Conversion to low-dose tacrolimus or rapamycin 3 months after kidney transplantation: a prospective, protocol biopsy-guided study. [2011.03]
A prospective, randomized trial of single-drug versus dual-drug immunosuppression in heart transplantation: the tacrolimus in combination, tacrolimus alone compared (TICTAC) trial. [2011.03]
Pharmacokinetics of sotrastaurin combined with tacrolimus or mycophenolic acid in de novo kidney transplant recipients. [2011.02.15]
Comparison of sirolimus with azathioprine in a tacrolimus-based immunosuppressive regimen in lung transplantation. [2011.02.01]
Pharmacokinetics for once-daily versus twice-daily tacrolimus formulations in de novo liver transplantation: a randomized, open-label trial. [2011.02]
Short-term outcomes of induction therapy with tacrolimus versus cyclophosphamide for active lupus nephritis: A multicenter randomized clinical trial. [2011.02]
Applicability of an exaggerated forearm wash test for efficacy testing of two corticosteroids, tacrolimus and glycerol, in topical formulations against skin irritation induced by two different irritants. [2011.02]
Prophylaxis of graft-versus-host disease in unrelated donor transplantation with pentostatin, tacrolimus, and mini-methotrexate: a phase I/II controlled, adaptively randomized study. [2011.01.20]
An investigation comparing the efficacy of topical ocular application of tacrolimus and cyclosporine in dogs. [2011]
Randomised, double-blind, placebo-controlled study of tacrolimus in myasthenia
gravis. [2011]
Efficacy of tacrolimus 0.1% ointment in cutaneous lupus erythematosus: a
multicenter, randomized, double-blind, vehicle-controlled trial. [2011]
A double-blind, randomized, placebo-controlled trial of topical tacrolimus 0·1%
vs. clobetasol propionate 0·05% in childhood vitiligo. [2011]
Efficacy and safety of additional use of tacrolimus in patients with early
rheumatoid arthritis with inadequate response to DMARDs--a multicenter,
double-blind, parallel-group trial. [2011]
A comparison of short-term exposure of once-daily extended release tacrolimus and twice-daily cyclosporine on renal function in healthy volunteers. [2010.12.15]
Evaluation of methylprednisolone aceponate, tacrolimus and combination thereof in the psoriasis plaque test using sum score, 20-MHz-ultrasonography and optical coherence tomography. [2010.12]
Population pharmacokinetic analysis of mycophenolic acid coadministered with either tasocitinib (CP-690,550) or tacrolimus in adult renal allograft recipients. [2010.12]
Tacrolimus once daily (ADVAGRAF) versus twice daily (PROGRAF) in de novo renal transplantation: a randomized phase III study. [2010.12]
ATG-Fresenius Treatment and Low-Dose Tacrolimus: Results of a Randomized Controlled Trial in Liver Transplantation. [2010.10]
Pre-transplant pharmacokinetic profiling and tacrolimus requirements post-transplant. [2010.10]
Preliminary results of a prospective randomized study of cyclosporine versus tacrolimus in the development of cardiac allograft vasculopathy at 1 year after heart transplantation. [2010.10]
Pharmacokinetics of once- versus twice-daily tacrolimus formulations in kidney transplant patients receiving expanded criteria deceased donor organs: a single-center, randomized study. [2010.10]
Once-Daily Prolonged-Release Tacrolimus (ADVAGRAF) Versus Twice-Daily Tacrolimus (PROGRAF) in Liver Transplantation. [2010.10]
Comparison of Sirolimus to Azathioprine in a Tacrolimus Based Immunosuppressive Regimen in Lung Transplantation. [2010.09.10]
A randomized phase II trial comparing tacrolimus and mycophenolate mofetil to tacrolimus and methotrexate for acute graft-versus-host disease prophylaxis. [2010.07]
Assessing renal function with daclizumab induction and delayed tacrolimus introduction in liver transplant recipients. [2010.06.27]
Thymoglobulin induction and sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids. [2010.06.27]
Quality of life and health-related utility analysis of adults with moderate and severe atopic dermatitis treated with tacrolimus ointment vs. topical corticosteroids. [2010.06]
Optimization of initial tacrolimus dose using pharmacogenetic testing. [2010.06]
Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study. [2010.06]
Interaction between everolimus and tacrolimus in renal transplant recipients: a pharmacokinetic controlled trial. [2010.04.27]
A randomized, placebo-controlled clinical trial of tacrolimus ophthalmic suspension 0.1% in severe allergic conjunctivitis. [2010.04]
Tacrolimus combined with corticosteroids in treatment of nephrotic idiopathic membranous nephropathy: a multicenter randomized controlled trial. [2010.03]
One-year treatment with 0.1% tacrolimus ointment versus a corticosteroid regimen in adults with moderate to severe atopic dermatitis: A randomized, double-blind, comparative trial. [2010.03]
Polyoxyl 60 hydrogenated castor oil free nanosomal formulation of immunosuppressant Tacrolimus: pharmacokinetics, safety, and tolerability in rodents and humans. [2010.03]
Efficacy of tacrolimus 0.03% ointment as second-line treatment for children with moderate-to-severe atopic dermatitis: evidence from a randomized, double-blind non-inferiority trial vs. fluticasone 0.005% ointment. [2010.03]
Time-kinetic study of repigmentation in vitiligo patients by tacrolimus or pimecrolimus. [2010.03]
Randomized trial of cyclosporine and tacrolimus therapy with steroid withdrawal in living-donor renal transplantation: 5-year follow-up. [2010.02]
Tacrolimus combined with two different corticosteroid-free regimens compared with a standard triple regimen in renal transplantation: one year observational results. [2010.01]
Safety and efficacy of tacrolimus ointment versus pimecrolimus cream in the treatment of patients with atopic dermatitis previously treated with corticosteroids. [2010]
A randomized, placebo-controlled clinical trial of tacrolimus ophthalmic
suspension 0.1% in severe allergic conjunctivitis. [2010]
Efficacy of tacrolimus 0.03% ointment as second-line treatment for children with
moderate-to-severe atopic dermatitis: evidence from a randomized, double-blind
non-inferiority trial vs. fluticasone 0.005% ointment. [2010]
Long-term graft function with tacrolimus and cyclosporine in renal transplantation: paired kidney analysis. [2009.12]
Management of young patients with lupus nephritis using tacrolimus administered as a single daily dose. [2009.12]
Outcome of recurrent hepatitis C virus after liver transplantation in a randomized trial of tacrolimus monotherapy versus triple therapy. [2009.12]
Health-related utility among adults with atopic dermatitis treated with 0.1% tacrolimus ointment as maintenance therapy over the long term: findings from the Protopic CONTROL study. [2009.12]
A randomized trial comparing renal function in older kidney transplant patients following delayed versus immediate tacrolimus administration. [2009.11.15]
Thymoglobulin induction in liver transplant recipients with a tacrolimus, mycophenolate mofetil, and steroid immunosuppressive regimen: a five-year randomized prospective study. [2009.11]
A prospective randomized open study in liver transplant recipients: daclizumab, mycophenolate mofetil, and tacrolimus versus tacrolimus and steroids. [2009.11]
Pharmacokinetics for once- versus twice-daily tacrolimus formulations in de novo kidney transplantation: a randomized, open-label trial. [2009.11]
An open randomized study to compare narrow band UVB, topical pimecrolimus and topical tacrolimus in the treatment of vitiligo. [2009.11]
Factors associated with progression of interstitial fibrosis in renal transplant patients receiving tacrolimus and mycophenolate mofetil. [2009.10.15]
A randomized, double-blind, pharmacokinetic study of oral maribavir with tacrolimus in stable renal transplant recipients. [2009.10]
Effectiveness of substituting cyclosporin A with tacrolimus in reducing gingival overgrowth in renal transplant patients. [2009.09.01]
UGT1A9 -275T>A/-2152C>T polymorphisms correlate with low MPA exposure and acute rejection in MMF/tacrolimus-treated kidney transplant patients. [2009.09]
Response of vitiligo to once- vs. twice-daily topical tacrolimus: a controlled prospective, randomized, observer-blinded trial. [2009.08]
Superiority of tacrolimus 0.1% ointment compared with fluticasone 0.005% in adults with moderate to severe atopic dermatitis of the face: results from a randomized, double-blind trial. [2009.08]
Efficacy and safety of tacrolimus versus cyclosporine in children with steroid-resistant nephrotic syndrome: a randomized controlled trial. [2009.05]
The pharmacokinetics of tacrolimus after first and repeated dosing with 0.03% ointment in infants with atopic dermatitis. [2009.04]
Efficacy and safety of tacrolimus ointment 0.1% vs. betamethasone 17-valerate 0.1% in the treatment of chronic paronychia: an unblinded randomized study. [2009.04]
Tacrolimus pharmacokinetic drug interactions: effect of prednisone, mycophenolic acid or sirolimus. [2009.02]
Pharmacokinetics, efficacy, and safety of mycophenolate mofetil in combination with standard-dose or reduced-dose tacrolimus in liver transplant recipients. [2009.02]
Delayed introduction of reduced-dose tacrolimus, and renal function in liver transplantation: the 'ReSpECT' study. [2009.02]
Multicentre prospective randomised trial of tacrolimus, azathioprine and prednisolone with or without basiliximab: two-year follow-up data. [2009.01]
Efficacy of topical tacrolimus 0.1% in active plaque morphea: randomized, double-blind, emollient-controlled pilot study. [2009]
Efficacy and safety of tacrolimus for lupus nephritis: a placebo-controlled double-blind multicenter study. [2009]
Patient outcomes in two steroid-free regimens using tacrolimus monotherapy after daclizumab induction and tacrolimus with mycophenolate mofetil in liver transplantation. [2008.12.27]
Tacrolimus monotherapy in liver transplantation: one-year results of a prospective, randomized, double-blind, placebo-controlled study. [2008.12]
Three times weekly tacrolimus ointment reduces relapse in stabilized atopic dermatitis: a new paradigm for use. [2008.12]
Proactive disease management with 0.03% tacrolimus ointment for children with atopic dermatitis: results of a randomized, multicentre, comparative study. [2008.12]
Economic evaluation of maintenance treatment with tacrolimus 0.1% ointment in adults with moderate to severe atopic dermatitis. [2008.12]
Two-year observation of a randomized trial on tacrolimus-based therapy with withdrawal of steroids or mycophenolate mofetil after renal transplantation. [2008.12]
Adult patients with moderate atopic dermatitis: tacrolimus ointment versus pimecrolimus cream. [2008.12]
Pharmacokinetics of emtricitabine/tenofovir disoproxil fumarate and tacrolimus at steady state when administered alone or in combination. [2008.12]
Comparison of sirolimus plus tacrolimus versus sirolimus plus cyclosporine in high-risk renal allograft recipients: results from an open-label, randomized trial. [2008.11.15]
Five-year study of tacrolimus as secondary intervention versus continuation of cyclosporine in renal transplant patients at risk for chronic renal allograft failure. [2008.10.15]
Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus. [2008.10]
Long-term effect of tacrolimus therapy in patients with refractory ulcerative colitis. [2008.09.01]
Combination therapy with tacrolimus and mycophenolate mofetil: effects of early and late minimization of mycophenolate mofetil after renal transplant. [2008.09]
Improved renal function, with similar proteinuria, after two years of early tacrolimus withdrawal from a regimen of sirolimus plus tacrolimus. [2008.08.27]
Tacrolimus (FK506) for induction of remission in refractory ulcerative colitis. [2008.07.16]
Optimizing tacrolimus therapy in the maintenance of renal allografts: 12-month results. [2008.07.15]
Randomized trial of mycophenolate mofetil versus enteric-coated mycophenolate sodium in primary renal transplant recipients given tacrolimus and daclizumab/thymoglobulin: one year follow-up. [2008.07.15]
Topical tacrolimus 0.1% improves symptoms of hand dermatitis in patients treated with a prednisone taper. [2008.07]
Proactive treatment of atopic dermatitis in adults with 0.1% tacrolimus ointment. [2008.07]
Alemtuzumab (Campath-1H) and tacrolimus monotherapy after renal transplantation: results of a prospective randomized trial. [2008.07]
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