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Prograf (Tacrolimus) - Summary

 

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WARNING

Increased susceptibility to infection and the possible development of lymphoma may result from immunosuppression. Only physicians experienced in immunosuppressive therapy and management of organ transplant patients should prescribe Prograf. Patients receiving the drug should be managed in facilities equipped and staffed with adequate laboratory and supportive medical resources. The physician responsible for maintenance therapy should have complete information requisite for the follow-up of the patient.

 

PROGRAF SUMMARY

PROGRAF®
tacrolimus capsules
tacrolimus injection (for intravenous infusion only)

Prograf is available for oral administration as capsules (tacrolimus capsules) containing the equivalent of 0.5 mg, 1 mg or 5 mg of anhydrous tacrolimus.

Prograf is indicated for the prophylaxis of organ rejection in patients receiving allogeneic liver or kidney transplants. It is recommended that Prograf be used concomitantly with adrenal corticosteroids. Because of the risk of anaphylaxis, Prograf injection should be reserved for patients unable to take Prograf capsules orally.

PROGRAF NEWS HIGHLIGHTS

Media Articles Related to Prograf (Tacrolimus)

People Living With HIV/AIDS In Canada Have Difficulty Obtaining Organ Transplants, Advocates Say At AIDS Conference
Source: Transplants / Organ Donations News From Medical News Today [2008.08.08]

Researchers Find Link Between Organ Transplants, Cancer
Source: MedicineNet Kidney Cancer Specialty [2008.07.17]

Fatal Organ Transplants From Rabies
Source: MedicineNet Rabies Specialty [2004.07.02]

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Published Studies Related to Prograf (Tacrolimus)

Tacrolimus (FK506) for induction of remission in refractory ulcerative colitis. [2008.07.16]

Topical tacrolimus 0.1% improves symptoms of hand dermatitis in patients treated with a prednisone taper. [2008.07]

Proactive treatment of atopic dermatitis in adults with 0.1% tacrolimus ointment. [2008.07]

Proactive treatment of atopic dermatitis in adults with 0.1% tacrolimus ointment. [2008.06]

Intermittent therapy for flare prevention and long-term disease control in stabilized atopic dermatitis: a randomized comparison of 3-times-weekly applications of tacrolimus ointment versus vehicle. [2008.06]

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Clinical Trials Related to Prograf (Tacrolimus)

A Study to Evaluate and Compare the Efficacy and Safety of FK506MR vs Prograf® in Stable Liver Transplantation Patients [Active, not recruiting]

A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Liver Transplantation [Active, not recruiting]

A Study to Compare the Efficacy and Safety of FK506MR vs Prograf® in Patients Undergoing Kidney Transplantation [Active, not recruiting]

Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects [Completed]

Comparative Study of Modified Release (MR) Tacrolimus/MMF in de Novo Kidney Transplant Recipients [Active, not recruiting]

more>>

Page last updated: 2008-08-11

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