Proctofoam (Hydrocortisone Acetate / Pramoxine Hydrochloride) - Summary

PROCTOFOAM SUMMARY

Proctofoam®-HC (hydrocortisone acetate 1% and pramoxine hydrochloride 1%) is a topical aerosol foam for anal use containing hydrocortisone acetate 1% and pramoxine hydrochloride 1% in a hydrophilic base containing cetyl alcohol, emulsifying wax, methylparaben, polyoxyethylene-10 stearyl ether, propylene glycol, propylparaben, purified water, trolamine, and inert propellants: isobutane and propane.

Proctofoam®-HC is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses of the anal region.

PROCTOFOAM NEWS HIGHLIGHTS

Published Studies Related to Proctofoam (Hydrocortisone / Pramoxine)

Effect of transdermal iontophoresis codelivery of hydrocortisone on metoclopramide pharmacokinetics and skin-induced reactions in human subjects. [1999.10]

Arginine blocks the inhibitory effect of hydrocortisone on circulating growth hormone levels in patients with acromegaly. [1993.05]

Prevention of peritoneal adhesions in rats with verapamil, hydrocortisone sodium succinate, and phosphatidylcholine. [1992.01]

more>>

Clinical Trials Related to Proctofoam (Hydrocortisone / Pramoxine)

Correlation Salivary Cortisol and Free Serum Cortisol to Total Serum Cortisol in MICU Septic Shock [Recruiting]

Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis [Recruiting]

Cortisol Control of Human Inflammatory Responses to Endotoxin [Completed]

The Safety of Proctofoam-HC in the Third Trimester of Pregnancy [Recruiting]

Efficacy Study of Low-Dose Hydrocortisone Treatment for Fibromyalgia [Completed]

more>>