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Prochlorperazine Injection (Prochlorperazine Edisylate Injection) - Summary

 

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SUMMARY

Prochlorperazine Edisylate Injection, USP
Rx only

Prochlorperazine Edisylate Injection, an antiemetic and antipsychotic, is a sterile solution intended for intramuscular or intravenous administration.

Each mL contains prochlorperazine 5 mg as the edisylate, monobasic sodium phosphate monohydrate 5 mg, sodium tartrate dihydrate 12 mg, saccharin sodium 0.9 mg and benzyl alcohol 7.5 mg in Water for Injection. pH 4.2-6.2.

Prochlorperazine Edisylate (prochlorperazine) is indicated for the following:

To control severe nausea and vomiting. For the treatment of schizophrenia.

Prochlorperazine has not been shown effective in the management of behavioral complications in patients with mental retardation.

NEWS HIGHLIGHTS RELATED TO PROCHLORPERAZINE INJECTION

Published Studies Related to Prochlorperazine Injection

Droperidol vs. prochlorperazine for benign headaches in the emergency department. [2001.09]

The prophylactic antiemetic efficacy of prochlorperazine and ondansetron in nasal septal surgery: a randomized double-blind comparison. [1996.10]

Intramuscular prochlorperazine versus metoclopramide as single-agent therapy for the treatment of acute migraine headache. [1996.05]

Comparison of ondansetron and prochlorperazine for the prevention of nausea and vomiting after adenotonsillectomy. [1996.03]

Randomized, double-blind comparison of a prochlorperazine-based versus a metoclopramide-based antiemetic regimen in patients undergoing autologous bone marrow transplantation. [1995.12.01]

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Clinical Trials Related to Prochlorperazine Injection

StaccatoŽ Prochlorperazine for Inhalation [Completed]

Prochlorperazine vs Imitrex for Acute Migraine in the Emergency Department [Completed]

Staccato Prochlorperazine in Patients With Migraine Headache [Completed]

StaccatoŽ Prochlorperazine for Inhalation in Migraine [Completed]

Staccato Prochlorperazine Thorough QT/QTc Study [Completed]

more>>

Page last updated: 2007-05-02

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