Probenecid (Probenecid) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The following adverse reactions have been observed and within each category are listed in order of decreasing severity.

Central Nervous System: headache, dizziness.

Metabolic: precipitation of acute gouty arthritis.

Gastrointestinal: hepatic necrosis, vomiting, nausea, anorexia, sore gums.

Genitourinary: nephrotic syndrome, uric acid stones with or without hematuria, renal colic, costovertebral pain, urinary frequency.

Hypersensitivity: anaphylaxis, fever, urticaria, pruritus.

Hematologic: aplastic anemia, leukopenia, hemolytic anemia which in some patients could be related to genetic deficiency of glucose-6-phosphate dehydrogenase in red blood cells, anemia.

Integumentary: dermatitis, alopecia, flushing.

REPORTS OF SUSPECTED PROBENECID SIDE EFFECTS / ADVERSE REACTIONS

Possible Probenecid side effects / adverse reactions in 67 year old male

Reported by a consumer/non-health professional from United States on 2012-02-15

Patient: 67 year old male weighing 89.8 kg (197.6 pounds)

Reactions: Blood Creatinine Increased

Suspect drug(s):
Probenecid

Other drugs received by patient: Nadolol; Azathioprine; Cyclosporine

Possible Probenecid side effects / adverse reactions in 37 year old male

Reported by a health professional (non-physician/pharmacist) from Belgium on 2012-06-26

Patient: 37 year old male weighing 58.0 kg (127.6 pounds)

Reactions: Therapeutic Response Decreased, Myelodysplastic Syndrome

Suspect drug(s):
Aranesp
    Dosage: 500 mug, q3wk
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-12-01

Probenecid
    Dosage: unk
    Indication: Nephropathy Toxic
    Start date: 2011-11-01
    End date: 2012-04-01

Vistide
    Dosage: unk
    Indication: Cytomegalovirus Infection
    Start date: 2011-11-01
    End date: 2012-04-01

Other drugs received by patient: Solian; Medrol; Mabthera; Neoral; Omeprazole; Mabthera

Possible Probenecid side effects / adverse reactions in 37 year old male

Reported by a physician from Belgium on 2012-07-04

Patient: 37 year old male weighing 58.0 kg (127.6 pounds)

Reactions: Therapeutic Response Decreased, Myelodysplastic Syndrome

Suspect drug(s):
Aranesp
    Dosage: 500 mug, q3wk
    Indication: Acute Myeloid Leukaemia
    Start date: 2011-12-01

Probenecid
    Dosage: unk
    Indication: Nephropathy Toxic
    Start date: 2011-11-01
    End date: 2012-04-01

Vistide
    Dosage: unk
    Indication: Cytomegalovirus Infection
    Start date: 2011-11-01
    End date: 2012-04-01

Other drugs received by patient: Mabthera; Medrol; Solian; Omeprazole; Neoral; Mabthera