Probenecid (Probenecid) - Summary

PROBENECID SUMMARY

PROBENECID
TABLETS, USP
mg

Probenecid is a uricosuric and renal tubular transport blocking agent.

Probenecid tablets are indicated for the treatment of the hyperuricemia associated with gout and gouty arthritis.

As an adjuvant to therapy with penicillin or with ampicillin, methicillin, oxacillin, cloxacillin, or nafcillin, for elevation and prolongation of plasma levels by whatever route the antibiotic is given.

PROBENECID NEWS HIGHLIGHTS

Published Studies Related to Probenecid

Reduction in non-glomerular renal clearance of the caffeine metabolite 1-methylxanthine by probenecid. [2007.08]

Effect of probenecid on the pharmacokinetics of carbamazepine in healthy subjects. [2005.06]

Different effects of three transporting inhibitors, verapamil, cimetidine, and probenecid, on fexofenadine pharmacokinetics. [2005.01]

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Clinical Trials Related to Probenecid

Safety and Tolerance of Zidovudine With Probenecid and the Effect of Probenecid on Zidovudine Pharmacokinetics Over Four Weeks [Completed]

Influence of Probenecid and Quinine on the Pharmacokinetics of Azidothymidine [Completed]

10-Propargyl-10-Deazaaminopterin Plus Probenecid in Treating Patients With Advanced Solid Tumors [Completed]

Evaluation of Alternative Oseltamivir (Tamiflu) Dosing Strategies. [Completed]

Evaluating the Transporter Protein Inhibitor Probenecid In Patients With Epilepsy [Recruiting]

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