Primaquine (Primaquine Phosphate) - Summary

PRIMAQUINE SUMMARY

PRIMAQUINE
PHOSPHATE
TABLETS, USP

Primaquine phosphate is 8-[(4-Amino-1-methylbutyl)amino]-6-methoxyquinoline phosphate, a synthetic compound with potent antimalarial activity. Each tablet contains 26.3 mg of Primaquine phosphate (equivalent to 15 mg of primaquine base). The dosage is customarily expressed in terms of the base.

Primaquine phosphate is indicated for the radical cure (prevention of relapse) of vivax malaria.

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PRIMAQUINE NEWS HIGHLIGHTS

Published Studies Related to Primaquine

A Randomized Open-Label Trial of Artesunate- Sulfadoxine-Pyrimethamine with or without Primaquine for Elimination of Sub-Microscopic P. falciparum Parasitaemia and Gametocyte Carriage in Eastern Sudan. [2007.12.12]

Primaquine Clears Submicroscopic Plasmodium falciparum Gametocytes that Persist after Treatment with Sulphadoxine-Pyrimethamine and Artesunate. [2007.10.10]

Primaquine for preventing relapses in people with Plasmodium vivax malaria. [2007.01.24]

Combined chloroquine, sulfadoxine/pyrimethamine and primaquine against Plasmodium falciparum in Central Java, Indonesia. [2006.11.14]

Efficacy of three chloroquine-primaquine regimens for treatment of Plasmodium vivax malaria in Colombia. [2006.10]

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Clinical Trials Related to Primaquine

Eight Week Primaquine Regimen for the Treatment of Vivax Malaria [Completed]

The Safety and Efficacy of Clindamycin and Primaquine in the Treatment of Mild - Moderate Pneumocystis Carinii Pneumonia in Patients With AIDS [Completed]

A Phase III Comparative Study of Dapsone / Trimethoprim and Clindamycin / Primaquine Versus Sulfamethoxazole / Trimethoprim in the Treatment of Mild-to-Moderate PCP in Patients With AIDS [Completed]

Randomized Trial of Two Antimalarial Treatments for Clearing Low Density P.Falciparum Parasitaemia in Sudan [Completed]

Mass-Drug Administration to Reduce Malaria Transmission [Active, not recruiting]

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