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Primacor (Milrinone Lactate) - Summary

 


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PRIMACOR SUMMARY

PRIMACOR, brand of milrinone lactate injection, is a member of a new class of bipyridine inotropic/vasodilator agents with phosphodiesterase inhibitor activity, distinct from digitalis glycosides or catecholamines.

PRIMACOR is indicated for the short-term intravenous treatment of patients with acute decompensated heart failure. Patients receiving PRIMACOR should be observed closely with appropriate electrocardiographic equipment. The facility for immediate treatment of potential cardiac events, which may include life threatening ventricular arrhythmias, must be available. The majority of experience with intravenous PRIMACOR has been in patients receiving digoxin and diuretics. There is no experience in controlled trials with infusions of PRIMACOR for periods exceeding 48 hours.


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PRIMACOR NEWS HIGHLIGHTS

Published Studies Related to Primacor (Milrinone)

Randomized Trial of Milrinone Versus Placebo for Prevention of Low Systemic Blood Flow in Very Preterm Infants. [2008.09.24]

Nitric oxide and milrinone: combined effect on pulmonary circulation after Fontan-type procedure: a prospective, randomized study. [2008.09]

[Efficacy of continuous intraoperative administration of low-dose milrinone during the circumflex artery anastomosis of off-pump coronary artery bypass] [2007.06]

Perioperative nesiritide versus milrinone in high-risk coronary artery bypass graft patients. [2007.03]

The metabolic and renal effects of adrenaline and milrinone in patients with myocardial dysfunction after coronary artery bypass grafting. [2007]

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Clinical Trials Related to Primacor (Milrinone)

Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery [Recruiting]

The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG [Suspended]

Prophylactic Use of Levosimendan Versus Milrinone in Open Heart Surgery in Infants [Recruiting]

Nesiritide in Transplant-Eligible Management of Congestive Heart Failure-TMAC [Terminated]

Levosimendan in Congenital Cardiac Surgery [Not yet recruiting]

more >>

Page last updated: 2008-11-03

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