SUMMARY
Prilocaine Hydrochloride 4% with epinephrine 1:200,000 injection is a sterile, non pyrogenic isotonic solution that contains a local anesthetic agent with epinephrine (as bitartrate) and is administered parenterally by injection.
Prilocaine Hydrochloride 4% with Epinephrine 1:200,000 injection is indicated for the production of local anesthesia in dentistry by nerve block or infiltration techniques. Only accepted procedures for these techniques as described in standard textbooks are recommended.
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NEWS HIGHLIGHTS
Published Studies Related to Prilocaine and Epinephrine (Prilocaine / Epinephrine)
Injection pain of prilocaine plain, mepivacaine plain, articaine with
epinephrine, and lidocaine with epinephrine. [2006]
In a double-blind study design, 1,391 consecutive patients in a general dental
practice received one of four different local anesthetics (articaine with
epinephrine, lidocaine with epinephrine, mepivacaine plain, or prilocaine plain)
via a maxillary buccal infiltration, palatal infiltration, or inferior alveolar
block injection...
Evaluation of prilocaine for the reduction of pain associated with transmucosal
anesthetic administration. [1999]
This investigation evaluated the use and efficacy of prilocaine HCl (4% plain
Citanest) for minimizing pain associated with the intraoral administration of
local anesthesia. Clinical anecdotes support the hypothesis that prilocaine
without a vasoconstrictor reduces pain during injection...
Prilocaine-phenylephrine and bupivacaine-phenylephrine topical anesthetics
compared with tetracaine-adrenaline-cocaine during repair of lacerations. [1998]
The effectiveness of two new topical anesthetics that do not contain cocaine
(prilocaine-phenylephrine and bupivacaine-phenylephrine) was compared with that
of tetracaine-adrenaline-cocaine (TAC) during laceration repair in children. This
study was a prospective, randomized, double-blind trial conducted in the
emergency department of a large children's hospital...
Intra-articular and subcutaneous prilocaine with adrenaline for pain relief in
day case arthroscopy of the knee joint. [1990]
A randomised, double-blind study was conducted to assess the influence of
intra-articular and subcutaneous prilocaine with adrenaline on postoperative pain
in day case arthroscopy of the knee. The time to first dose of oral analgesia
postoperatively was significantly prolonged in those patients receiving
prilocaine but no significant difference in analgesic effect was demonstrated at
4, 8, and 12 h after operation between the two groups..
Methemoglobin levels in generally anesthetized pediatric dental patients
receiving prilocaine versus lidocaine. [2013]
The purpose of this study was to measure and compare peak methemoglobin levels
and times to peak methemoglobin levels following the use of prilocaine and
lidocaine in precooperative children undergoing comprehensive dental
rehabilitation under general anesthesia...
Clinical Trials Related to Prilocaine and Epinephrine (Prilocaine / Epinephrine)
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysterosalpingography Practice [Not yet recruiting]
Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl [Completed]
In this prospective randomized study the investigators aimed to investigate difference of
the duration of spinal anesthesia, discharge times and efficacy between low dose heavy
Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl in outpatient minor anal surgery.
7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream [Recruiting]
Methemoglobin Levels in Generally Anesthetized Pediatric Dental Patients Receiving Local Anesthetics [Completed]
To establish and compare maximum methemoglobin blood levels and times to maximum
methemoglobin blood levels following the administration of the injectable local anesthetics
prilocaine and lidocaine when used for dental treatment in pediatric patients under general
anesthesia. Patients will be randomized into three equal study groups. Two of the study
groups will receive local anesthetic and the third group will not. Methemoglobin blood
levels will be non-invasively monitored and recorded throughout dental treatment for all
groups using a Masimo Radical-7 Pulse Co-Oximeter device.
Lidocaine-Prilocaine (EMLA) Cream as Analgesia in Hysteroscopy Practice [Completed]
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