Prepidil (Dinoprostone Vaginal) - Summary

PREPIDIL SUMMARY

Prepidil^® Gel
dinoprostone cervical gel

PREPIDIL Gel contains dinoprostone as the naturally occurring form of prostaglandin E₂ (PGE₂) and is designated chemically as (5Z, 11a, 13E, 15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid.

PREPIDIL Gel is indicated for ripening an unfavorable cervix in pregnant women at or near term with a medical or obstetrical need for labor induction.

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PREPIDIL NEWS HIGHLIGHTS

Published Studies Related to Prepidil (Dinoprostone Vaginal)

Misoprostol vaginal insert compared with dinoprostone vaginal insert: a randomized controlled trial. [2008.10]

Induction of labour in nulliparous and multiparous women: a UK, multicentre, open-label study of intravaginal misoprostol in comparison with dinoprostone. [2008.09]

A prospective randomized trial of labor induction with vaginal controlled-release dinoprostone inserts with or without oxytocin and misoprostol+oxytocin. [2008]

Efficacy and safety of six hourly vaginal misoprostol versus intracervical dinoprostone: a randomized controlled trial. [2007.08]

Concurrent oxytocin with dinoprostone pessary versus dinoprostone pessary in labour induction of nulliparas with an unfavourable cervix: a randomised placebo-controlled trial. [2007.07]

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Clinical Trials Related to Prepidil (Dinoprostone Vaginal)

Safety/Efficacy Study Comparing the Misoprostol Vaginal Insert to Cervidil for Cervical Ripening and Induction of Labor [Completed]

Cervical Ripening Before Induction of Labour at Term: a Randomised Comparison of Prostin vs Propess [Completed]

Labour Induction With Misoprostol, Dinoprostone and Bard Catheter [Completed]

Comparison of Misoprostol and PGE2 Gel for Induction of Labour in Women With Premature Rupture of Membranes at Term [Recruiting]

Headache Inducing Characteristics and Possible Changes in Cerebral Blood Flow After Administration of PGE2 [Completed]

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